2008
Evaluation of MR markers that predict survival in patients with newly diagnosed GBM prior to adjuvant therapy
Saraswathy S, Crawford FW, Lamborn KR, Pirzkall A, Chang S, Cha S, Nelson SJ. Evaluation of MR markers that predict survival in patients with newly diagnosed GBM prior to adjuvant therapy. Journal Of Neuro-Oncology 2008, 91: 69-81. PMID: 18810326, PMCID: PMC3022437, DOI: 10.1007/s11060-008-9685-3.Peer-Reviewed Original ResearchConceptsGlioblastoma multiformeRadiation therapyExternal beam radiation therapyLethal primary brain tumorProportional hazards analysisSurvival of patientsPrimary brain tumorsSpecific treatment protocolsBeam radiation therapyAdjuvant radiationAdjuvant therapySurgical resectionLesion burdenMR parametersPoor outcomeAnatomic lesionsPoor survivalScanner field strengthTreatment protocolStudy populationFocal therapyHigh riskBrain tumorsPatientsPredictive value
2005
Differentiation of low-grade oligodendrogliomas from low-grade astrocytomas by using quantitative blood-volume measurements derived from dynamic susceptibility contrast-enhanced MR imaging.
Cha S, Tihan T, Crawford F, Fischbein NJ, Chang S, Bollen A, Nelson SJ, Prados M, Berger MS, Dillon WP. Differentiation of low-grade oligodendrogliomas from low-grade astrocytomas by using quantitative blood-volume measurements derived from dynamic susceptibility contrast-enhanced MR imaging. American Journal Of Neuroradiology 2005, 26: 266-73. PMID: 15709123, PMCID: PMC7974081.Peer-Reviewed Original ResearchConceptsBlood volume measurementsDSC-MR imagingLow-grade oligodendrogliomasMR imagingWorld Health Organization grade II astrocytomaGrade II astrocytomasContrast-enhanced MR imagingCerebral blood volume measurementsLow-grade astrocytomasContrast-enhanced MRLow-grade gliomasSpecific tumor markersDynamic susceptibility contrast-enhanced MR imagingMaximum relative CBVDiagnosis of gliomaSurgical resectionConsecutive patientsHistologic confirmationHistologic subtypeCommon subtypeHistopathologic evaluationMorphologic aberrationsTumor vascularityTumor markersAnatomic imaging