2013
Cortical Gyrification Induced by Fibroblast Growth Factor 2 in the Mouse Brain
Rash BG, Tomasi S, Lim HD, Suh CY, Vaccarino FM. Cortical Gyrification Induced by Fibroblast Growth Factor 2 in the Mouse Brain. Journal Of Neuroscience 2013, 33: 10802-10814. PMID: 23804101, PMCID: PMC3693057, DOI: 10.1523/jneurosci.3621-12.2013.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntimetabolitesAxonsBrain ChemistryBromodeoxyuridineCell CountCerebral CortexCerebral VentriclesDensitometryDependovirusDNA, ComplementaryFemaleFibroblast Growth Factor 2Green Fluorescent ProteinsImmunohistochemistryIn Situ HybridizationLymphoid Enhancer-Binding Factor 1MiceNeocortexPregnancyReal-Time Polymerase Chain ReactionRNAWnt3A ProteinConceptsVentricular zoneIntermediate neuronal progenitorsSubventricular zoneCortical gyrificationCortical primordiumRegion-specific actionsFibroblast growth factor-2ER81 expressionGrowth factor 2Ventricular injectionCortical layer structureBasal radial gliaCortical gyriRadial gliaMouse brainCortical hemEmbryonic day 11.5Neuronal progenitorsGyrus formationLEF1 expressionGyrificationNeurogenesisLissencephalic speciesFactor 2Impaired growth
1999
Identification, Chromosomal Assignment, and Expression Analysis of the Human Homeodomain-Containing Gene Orthopedia (OTP)
Lin X, State M, Vaccarino F, Greally J, Hass M, Leckman J. Identification, Chromosomal Assignment, and Expression Analysis of the Human Homeodomain-Containing Gene Orthopedia (OTP). Genomics 1999, 60: 96-104. PMID: 10458915, DOI: 10.1006/geno.1999.5882.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBase SequenceBrainChromosome BandingChromosome MappingChromosomes, Human, Pair 5DNA, ComplementaryDrosophila ProteinsExonsGene ExpressionGene Expression Regulation, DevelopmentalGenesHomeodomain ProteinsHumansImmunohistochemistryIn Situ Hybridization, FluorescenceIntronsMolecular Sequence DataNerve Tissue ProteinsRatsRats, Sprague-DawleySequence AlignmentSequence Analysis, DNASequence Homology, Amino AcidConceptsHuman cDNAHuman homologueRadiation hybrid panel mappingDeduced amino acid sequenceHelix transcription factorOpen reading frameAmino acid sequenceHuman HomeodomainChromosomal assignmentHomeodomain genesCell fateGenomic libraryTranscription factorsHuman chromosomesReading frameGene productsAcid sequenceHD geneExpression analysisC-terminusYAC clonesNovel polyclonal antibodyOrthopediaCell migration patternsHuman fetal brain tissue
1996
Characterization and Sequence Analysis of the Human Homeobox-Containing GeneGBX2
Lin X, Swaroop A, Vaccarino F, Murtha M, Haas M, Ji X, Ruddle F, Leckman J. Characterization and Sequence Analysis of the Human Homeobox-Containing GeneGBX2. Genomics 1996, 31: 335-342. PMID: 8838315, DOI: 10.1006/geno.1996.0056.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBase SequenceBrainCell LineChromosome MappingChromosomes, Human, Pair 2Cloning, MolecularDNA PrimersDNA, ComplementaryFemaleGene ExpressionGenomic LibraryHomeodomain ProteinsHumansMolecular Sequence DataPregnancyRodentiaSequence AnalysisSequence Homology, Amino AcidConceptsFetal brain cDNA libraryBrain cDNA libraryCDNA clonesCDNA librarySomatic cell hybrid analysisHuman fetal brain cDNA libraryCell hybrid analysisHuman genomic cloneAmino-terminal endAmino acid residuesHuman homeoboxesGenomic clonesHomologous genesGBX2 geneHomeobox genesCpG islandsNucleotide sequenceMouse embryosUntranslated regionProline residuesNorthern analysisAcid residuesSequence analysisGenesPolymerase chain reaction
1995
Fibroblast growth factor 2 increases Otx2 expression in precursor cells from mammalian telencephalon
Robel L, Ding M, James A, Lin X, Simeone A, Leckman J, Vaccarino F. Fibroblast growth factor 2 increases Otx2 expression in precursor cells from mammalian telencephalon. Journal Of Neuroscience 1995, 15: 7879-7891. PMID: 8613727, PMCID: PMC6577918, DOI: 10.1523/jneurosci.15-12-07879.1995.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBase SequenceCell CountCells, CulturedDNA, ComplementaryDose-Response Relationship, DrugEmbryo, MammalianEmbryonic and Fetal DevelopmentFibroblast Growth Factor 2Gene ExpressionGenes, HomeoboxIntermediate Filament ProteinsMolecular ProbesMolecular Sequence DataNerve Tissue ProteinsNestinRatsStem CellsTelencephalonConceptsOtx2 expressionPrecursor cellsDifferent developmental stagesPopulation of neuroblastsRegulation of neurogenesisHomeobox genesEffects of FGF2Regulated fashionPostmitotic cellsPrimary culturesFibroblast growth factorBasic fibroblast growth factorMammalian telencephalonOtx2Developmental stagesMammalian forebrainDLX1FGF2