2013
Hypoxia-Induced Developmental Delays of Inhibitory Interneurons Are Reversed by Environmental Enrichment in the Postnatal Mouse Forebrain
Komitova M, Xenos D, Salmaso N, Tran KM, Brand T, Schwartz ML, Ment L, Vaccarino FM. Hypoxia-Induced Developmental Delays of Inhibitory Interneurons Are Reversed by Environmental Enrichment in the Postnatal Mouse Forebrain. Journal Of Neuroscience 2013, 33: 13375-13387. PMID: 23946395, PMCID: PMC3742925, DOI: 10.1523/jneurosci.5286-12.2013.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell Adhesion Molecules, NeuronalCerebral CortexChromatography, High Pressure LiquidDisease Models, AnimalExtracellular Matrix ProteinsGene Knock-In TechniquesHousing, AnimalHypoxiaImmunohistochemistryInterneuronsMiceMice, Inbred C57BLMice, TransgenicNerve Tissue ProteinsParvalbuminsProsencephalonReelin ProteinSerine EndopeptidasesSomatostatinConceptsCortical interneuronsNormoxic controlsMarker expressionPostnatal cortical developmentVasoactive intestinal peptidePostnatal day 3Central nervous systemTotal GABA contentImpact of hypoxicPostnatal mouse forebrainEnvironmental enrichmentIntestinal peptideGABAergic interneuronsFrontal neocortexInhibitory interneuronsCortical developmentMouse modelReelin expressionInterneuron numbersNervous systemDay 3Cognitive impairmentInterneuronsHousing miceRLN expression
1993
Induction of immediate early genes by cyclic AMP in primary cultures of neurons from rat cerebral cortex
Vaccarino FM, Hayward MD, Le HN, Hartigan DJ, Duman RS, Nestler EJ. Induction of immediate early genes by cyclic AMP in primary cultures of neurons from rat cerebral cortex. Brain Research 1993, 19: 76-82. PMID: 8103187, DOI: 10.1016/0169-328x(93)90151-e.Peer-Reviewed Original ResearchMeSH Keywords2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepineAnimalsAnimals, NewbornBucladesineCells, CulturedCerebral CortexColforsinCyclic AMPDNA-Binding ProteinsDopamine AgentsEarly Growth Response Protein 1ErgolinesGene Expression RegulationGenes, fosGenes, junGlutamatesGlutamic AcidImmediate-Early ProteinsImmunohistochemistryKineticsNeurogliaNeuronsQuinpiroleRatsRNA, MessengerSecond Messenger SystemsTranscription FactorsVasoactive Intestinal PeptideConceptsVasoactive intestinal peptideRat cerebral cortexCerebral cortexExcitatory amino acid receptor antagonistsDibutyryl cAMPAmino acid receptor antagonistsPrimary culturesC-fosDihydropyridine-sensitive calcium channelsAcid receptor antagonistsIEG inductionCalcium-free mediumCAMP second messenger pathwayIEGs c-fosSKF 38393Immediate-early gene transcription factorsIntestinal peptideReceptor antagonistReceptor agonistSecond messenger pathwaysCalcium channelsDifferentiated neuronsBrief stimulationImmediate early genesIEG expression