Fibroblast Growth Factor 2 Is Required for Maintaining the Neural Stem Cell Pool in the Mouse Brain Subventricular Zone
Zheng W, Nowakowski RS, Vaccarino FM. Fibroblast Growth Factor 2 Is Required for Maintaining the Neural Stem Cell Pool in the Mouse Brain Subventricular Zone. Developmental Neuroscience 2004, 26: 181-196. PMID: 15711059, DOI: 10.1159/000082136.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBiomarkersBrainCell Cycle ProteinsCell DifferentiationCell DivisionCell LineageCell ProliferationCerebral CortexDown-RegulationImmunohistochemistryLateral VentriclesMiceMice, KnockoutNeurogliaNeuronsOlfactory BulbReceptor Protein-Tyrosine KinasesReceptor, Fibroblast Growth Factor, Type 2Receptors, Fibroblast Growth FactorStem CellsConceptsStem cell poolNeural stem cellsFgf2 knockout miceSlower cell cycle kineticsProgenitor cell populationsSubventricular zoneCell poolNeural stem cell poolGene productsProgenitor populationsFibroblast growth factor-2Olfactory bulbKnockout miceCell cycleOlfactory bulb neurogenesisMolecular markersSmaller olfactory bulbsGrowth factor 2Brain subventricular zoneAnterior subventricular zoneReceptor proteinGlial fibrillary acidic proteinCell cycle kineticsStem cellsFibrillary acidic protein