2022
Advanced in vitro models: Microglia in action
Cakir B, Kiral F, Park I. Advanced in vitro models: Microglia in action. Neuron 2022, 110: 3444-3457. PMID: 36327894, DOI: 10.1016/j.neuron.2022.10.004.Peer-Reviewed Original Research
2021
Brain connectivity inversely scales with developmental temperature in Drosophila
Kiral F, Dutta S, Linneweber G, Hilgert S, Poppa C, Duch C, von Kleist M, Hassan B, Hiesinger P. Brain connectivity inversely scales with developmental temperature in Drosophila. Cell Reports 2021, 37: 110145. PMID: 34936868, DOI: 10.1016/j.celrep.2021.110145.Peer-Reviewed Original Research
2020
Autophagy-dependent filopodial kinetics restrict synaptic partner choice during Drosophila brain wiring
Kiral F, Linneweber G, Mathejczyk T, Georgiev S, Wernet M, Hassan B, von Kleist M, Hiesinger P. Autophagy-dependent filopodial kinetics restrict synaptic partner choice during Drosophila brain wiring. Nature Communications 2020, 11: 1325. PMID: 32165611, PMCID: PMC7067798, DOI: 10.1038/s41467-020-14781-4.Peer-Reviewed Original Research
2018
Live Observation of Two Parallel Membrane Degradation Pathways at Axon Terminals
Jin E, Kiral F, Ozel M, Burchardt L, Osterland M, Epstein D, Wolfenberg H, Prohaska S, Hiesinger P. Live Observation of Two Parallel Membrane Degradation Pathways at Axon Terminals. Current Biology 2018, 28: 1027-1038.e4. PMID: 29551411, PMCID: PMC5944365, DOI: 10.1016/j.cub.2018.02.032.Peer-Reviewed Original ResearchConceptsSynaptic vesicle proteinsMembrane proteinsVesicle proteinsLive-imaging approachesPlasma membrane proteinsMembrane protein degradationIntact Drosophila brainsProtein degradation mechanismsMembrane cargoDegradative compartmentsNeuronal synaptobrevinProtein degradationDrosophila brainContinuous turnoverCell bodiesProteinDegradation pathwayLive observationDistinct classesSortingCargoCompartmentsSynaptobrevinDegradationRab7