2023
Principles for task shifting hypertension and diabetes screening and referral: a qualitative study exploring patient, community health worker and healthcare professional perceptions in rural Uganda
Ingenhoff R, Munana R, Weswa I, Gaal J, Sekitoleko I, Mutabazi H, Bodnar B, Rabin T, Siddharthan T, Kalyesubula R, Knauf F, Nalwadda C. Principles for task shifting hypertension and diabetes screening and referral: a qualitative study exploring patient, community health worker and healthcare professional perceptions in rural Uganda. BMC Public Health 2023, 23: 881. PMID: 37173687, PMCID: PMC10176286, DOI: 10.1186/s12889-023-15704-w.Peer-Reviewed Original ResearchConceptsCommunity health workersNon-communicable diseasesHealthcare workersRural UgandaHealth workersCHW knowledgeNCD screeningDiabetes mellitusMiddle-income countriesCHW characteristicsHypertensionCHW programsCare deliveryHealthcare accessHealthcare professionalsReferralPatient accessHealthcare systemSuccessful program implementationDiabetesPatientsProfessionals' perceptionsFramework methodFocus group discussionsScreening
2022
Effectiveness of a community health worker-delivered care intervention for hypertension control in Uganda: study protocol for a stepped wedge, cluster randomized control trial
Ingenhoff R, Nandawula J, Siddharthan T, Ssekitoleko I, Munana R, Bodnar B, Weswa I, Kirenga B, Mutungi G, van der Giet M, Kalyesubula R, Knauf F. Effectiveness of a community health worker-delivered care intervention for hypertension control in Uganda: study protocol for a stepped wedge, cluster randomized control trial. Trials 2022, 23: 440. PMID: 35610712, PMCID: PMC9128241, DOI: 10.1186/s13063-022-06403-9.Peer-Reviewed Original ResearchConceptsCommunity health workersNon-communicable diseasesUncontrolled hypertensionBlood pressureCardiovascular disease risk assessmentHealthy lifestyle counselingMonthly household visitsBlood pressure controlSub-Saharan African settingPatient-related factorsPrimary care levelStepped-wedge clusterMedical treatment outcomeMajority of LMICsMulti-component interventionDisease risk assessmentNCD clinicsHypertension controlHypertensive patientsLifestyle counselingAdult patientsHTN managementMiddle-income countriesMedication adherenceEntire cohort
2021
Acceptability of patient-centered hypertension education delivered by community health workers among people living with HIV/AIDS in rural Uganda
Batte C, Mukisa J, Rykiel N, Mukunya D, Checkley W, Knauf F, Kalyesubula R, Siddharthan T. Acceptability of patient-centered hypertension education delivered by community health workers among people living with HIV/AIDS in rural Uganda. BMC Public Health 2021, 21: 1343. PMID: 34233648, PMCID: PMC8264981, DOI: 10.1186/s12889-021-11411-6.Peer-Reviewed Original ResearchConceptsCommunity health workersHIV/AIDSPatient-centered educationHealth workersRural UgandaSpecific health educationPrevalence of hypertensionManagement of hypertensionImproved health outcomesDisease-specific informationSelf-perceived skill levelFocus group discussionsMiddle-income countriesHypertension educationHealth facilitiesPatient questionsHypertensionHealth outcomesPLWHAHealth educationNakaseke districtHealth interventionsLMIC settingsFurther studiesHTN
2019
Challenges to hypertension and diabetes management in rural Uganda: a qualitative study with patients, village health team members, and health care professionals
Chang H, Hawley NL, Kalyesubula R, Siddharthan T, Checkley W, Knauf F, Rabin TL. Challenges to hypertension and diabetes management in rural Uganda: a qualitative study with patients, village health team members, and health care professionals. International Journal For Equity In Health 2019, 18: 38. PMID: 30819193, PMCID: PMC6394065, DOI: 10.1186/s12939-019-0934-1.Peer-Reviewed Original ResearchConceptsHealth care professionalsVillage health team membersHealth team membersCare professionalsRural UgandaPrevalence of hypertensionCommunity health workersIndividual health care professionalsUgandan health care systemHealth care systemLifestyle factorsDiabetes careDM managementHealth workersHypertensionPatientsNakaseke districtHealth system reformPreventable aspectsMedication accessibilityCare systemLack of awarenessRural settingsPotential roleDiabetes
2016
Oxalate-induced chronic kidney disease with its uremic and cardiovascular complications in C57BL/6 mice
Mulay SR, Eberhard JN, Pfann V, Marschner JA, Darisipudi MN, Daniel C, Romoli S, Desai J, Grigorescu M, Kumar SV, Rathkolb B, Wolf E, Hrabě de Angelis M, Bäuerle T, Dietel B, Wagner CA, Amann K, Eckardt KU, Aronson PS, Anders HJ, Knauf F. Oxalate-induced chronic kidney disease with its uremic and cardiovascular complications in C57BL/6 mice. American Journal Of Physiology. Renal Physiology 2016, 310: f785-f795. PMID: 26764204, PMCID: PMC5504458, DOI: 10.1152/ajprenal.00488.2015.Peer-Reviewed Original ResearchConceptsC57BL/6 miceChronic kidney disease researchOxalate-rich dietChronic kidney diseaseFemale C57BL/6 miceArterial hypertensionCardiovascular complicationsKidney disease researchAtubular glomeruliInterstitial inflammationRenal histologyTubular damageKidney diseaseCardiac fibrosisMetabolic acidosisNormochromic anemiaTissue involvementHistological changesHuman CKDCKDExperimental animalsComplicationsInducible modelControl dietFibrosis