Epigenetic molecular underpinnings of brain structural-functional connectivity decoupling in patients with major depressive disorder
Tang L, Zhao P, Pan C, Song Y, Zheng J, Zhu R, Wang F, Tang Y. Epigenetic molecular underpinnings of brain structural-functional connectivity decoupling in patients with major depressive disorder. Journal Of Affective Disorders 2024, 363: 249-257. PMID: 39029702, DOI: 10.1016/j.jad.2024.07.110.Peer-Reviewed Original ResearchMajor depressive disorderMajor depressive disorder patientsStructural-functional connectivityHPA axisDepressive disorderIncreased susceptibility to MDDSusceptibility to major depressive disorderMajor depressive disorder treatmentHealthy controlsStress-related disordersBrain network dynamicsMultimodal neuroimaging dataGender-matched healthy controlsSubcortical regionsNeuroimaging dataChronic stressCortical regionsNodal levelMedical statusFunctional networksCRHR1FKBP5CpG sitesDisordersMolecular underpinnings