2009
Neuregulin 1 genetic variation and anterior cingulum integrity in patients with schizophrenia and healthy controls.
Wang F, Jiang T, Sun Z, Teng SL, Luo X, Zhu Z, Zang Y, Zhang H, Yue W, Qu M, Lu T, Hong N, Huang H, Blumberg HP, Zhang D. Neuregulin 1 genetic variation and anterior cingulum integrity in patients with schizophrenia and healthy controls. Journal Of Psychiatry And Neuroscience 2009, 34: 181-6. PMID: 19448847, PMCID: PMC2674970.Peer-Reviewed Original ResearchConceptsAnterior cingulumFractional anisotropyHealthy controlsBrain regionsDiagnosis of schizophreniaDiffusion tensorWhite matter connectivityHealthy menWhite matter structuresT carriersMyelin integrityTT subgroupPatientsProminent involvementT alleleReciprocal connectionsAnterior componentC alleleCingulum bundleSchizophrenia groupGenetic susceptibilityCingulum fractional anisotropyNeuregulin1SchizophreniaSmall sample size
2008
Abnormal anterior cingulum integrity in bipolar disorder determined through diffusion tensor imaging
Wang F, Jackowski M, Kalmar JH, Chepenik LG, Tie K, Qiu M, Gong G, Pittman BP, Jones MM, Shah MP, Spencer L, Papademetris X, Constable RT, Blumberg HP. Abnormal anterior cingulum integrity in bipolar disorder determined through diffusion tensor imaging. The British Journal Of Psychiatry 2008, 193: 126-129. PMID: 18669996, PMCID: PMC2732002, DOI: 10.1192/bjp.bp.107.048793.Peer-Reviewed Original ResearchConceptsBipolar disorderWhite matter connectionsFractional anisotropyAnterior cingulumPosterior cingulumAbnormal white matter integrityWhite matter abnormalitiesBipolar disorder groupAnterior cingulate cortexDiffusion tensorWhite matter integrityHealthy groupCingulate cortexNeural systemsHealthy participantsDisorder groupDisordersAbnormalitiesCingulumConvergent evidenceGroupParticipantsEmotional regulation