GABA Changes with Vigabatrin in the Developing Human Brain
Novotny E, Hyder F, Shevell M, Rothman D. GABA Changes with Vigabatrin in the Developing Human Brain. Epilepsia 1999, 40: 462-466. PMID: 10219272, DOI: 10.1111/j.1528-1157.1999.tb00741.x.Peer-Reviewed Original ResearchConceptsBrain GABA levelsGABA levelsBrain GABAVGB treatmentRole of GABASeizure controlGABA changesSeizure susceptibilityPediatric epilepsyEpileptic focusOccipital lobeNervous systemEpileptic regionsVigabatrinEpilepsyGABAGABA metabolismTreatmentAge 1Noninvasive measurementHuman brainSubjectsDrugsFivefold increaseChildren