1999
Rapid Exchange of A:T Base Pairs Is Essential for Recognition of DNA Homology by Human Rad51 Recombination Protein
Gupta R, Folta-Stogniew E, O'Malley S, Takahashi M, Radding C. Rapid Exchange of A:T Base Pairs Is Essential for Recognition of DNA Homology by Human Rad51 Recombination Protein. Molecular Cell 1999, 4: 705-714. PMID: 10619018, DOI: 10.1016/s1097-2765(00)80381-0.Peer-Reviewed Original ResearchConceptsRecognition of homologyBase pairsRad51 recombination proteinT base pairsRecombination proteinsHuman Rad51Genetic exchangeFluorescence resonance energy transferUbiquitous familyMechanism of recognitionDNA repairStrand exchangeDNA homologyBase substitutionsHomologyResonance energy transferDuplex DNAHelix destabilizationCritical roleBase mismatchesProteinSingle strandsRAD51Rapid exchangeKinetic analysis
1996
Base-Catalysis of Imino Proton Exchange in DNA: Effects of Catalyst upon DNA Structure and Dynamics
Folta-Stogniew E, Russu I. Base-Catalysis of Imino Proton Exchange in DNA: Effects of Catalyst upon DNA Structure and Dynamics. Biochemistry 1996, 35: 8439-8449. PMID: 8679602, DOI: 10.1021/bi952932z.Peer-Reviewed Original ResearchConceptsDNA dodecamerProton exchangeExchange catalystImino proton exchangeDQF-COSY experimentsImino protonsEffect of catalystNon-exchangeable protonsSelf-complementary DNA dodecamerNucleic acid moleculesNMR spectroscopyDNA structureOverall correlation timeAcid moleculesSolution conformationBase catalysisCatalystProton resonancesWater protonsProton relaxationRate of exchangeNucleic acidsProtonsDodecamerCorrelation time