2020
Artificial intelligence in medical imaging: A radiomic guide to precision phenotyping of cardiovascular disease
Oikonomou EK, Siddique M, Antoniades C. Artificial intelligence in medical imaging: A radiomic guide to precision phenotyping of cardiovascular disease. Cardiovascular Research 2020, 116: 2040-2054. PMID: 32090243, PMCID: PMC7585409, DOI: 10.1093/cvr/cvaa021.Peer-Reviewed Original ResearchConceptsCardiac computed tomographyNon-invasive imagingCardiovascular imagingCardiovascular diseaseNon-invasive cardiovascular imagingCardiac CTCardiovascular risk stratificationFirst-line optionImportant clinical implicationsRisk stratificationUnstable patientsClinical careComputed tomographyCurrent evidenceClinical implicationsCardiac imagingRadiomics approachPatientsRadiomics methodTissue biologyCardiovascular diagnosticsDiseaseFuture studiesImagingPhenotyping
2018
Perivascular adipose tissue and coronary atherosclerosis
Mancio J, Oikonomou EK, Antoniades C. Perivascular adipose tissue and coronary atherosclerosis. Heart 2018, 104: 1654. PMID: 29853488, DOI: 10.1136/heartjnl-2017-312324.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsCardiometabolic risk profilePerivascular ATPerivascular adipose tissueAdipose tissueCardiovascular diseaseVascular wallEpicardial adipose tissueClose anatomical proximityAnti-atherogenic rolePotential therapeutic targetNovel clinical diagnostic toolsPromising new modalityCoronary inflammationCoronary atherosclerosisInflammatory statusNon-invasive imagingCardiovascular healthBody of evidenceAnatomical proximityCurrent evidenceTherapeutic targetAdjacent vasculatureClinical diagnostic toolRisk profileTherapeutic opportunities