2020
Real world cost and health outcomes of patients presented with chest pain in England: which is the most cost-effective first-line test?
Tsiachristas A, West H, Oikonomou E, Mihaylova B, Sabharwall N, Channon K, Neubauer S, Antoniades C. Real world cost and health outcomes of patients presented with chest pain in England: which is the most cost-effective first-line test? European Heart Journal 2020, 41: ehaa946.3547. DOI: 10.1093/ehjci/ehaa946.3547.Peer-Reviewed Original ResearchStable chest painFirst-line diagnostic testChest painClinical presentationNICE guidelinesDiagnostic testsClinical pathwayHealth Research Oxford Biomedical Research CentreStandardised ratesHealth outcomesReal-world clinical settingNon-invasive diagnostic testsChest pain clinicClass I indicationsRecent ESC guidelinesProportion of patientsManagement of patientsTomography coronary angiographyFirst-line investigationSubsequent diagnostic testsCurrent clinical pathwaysNational InstituteFirst-line diagnosticsFirst-line testClinical decision process
2019
Cardiac Computed Tomography
Oikonomou EK, West HW, Antoniades C. Cardiac Computed Tomography. Arteriosclerosis Thrombosis And Vascular Biology 2019, 39: 2207-2219. PMID: 31510795, DOI: 10.1161/atvbaha.119.312899.Peer-Reviewed Original ResearchConceptsCardiac computed tomographyComputed tomographyCoronary atherosclerosisCoronary plaque burdenAcute coronary syndromeCoronary artery diseaseFirst-line diagnostic testUnstable coronary plaquesMorphological plaque featuresCoronary syndromeInflammatory burdenArterial inflammationArtery diseaseCoronary lesionsPlaque burdenPlaque featuresPrognostic implicationsCoronary plaquesPerivascular fatHemodynamic significanceVulnerable plaquesDiagnostic testsMajor causeTomographyCurrent role