Euripedes C. Miguel, MD, PhD
Professor & Chair of Child and Adolescent Psychiatry, Department of Psychiatry, University of São Paulo School of MedicineAbout
Titles
Professor & Chair of Child and Adolescent Psychiatry, Department of Psychiatry, University of São Paulo School of Medicine
Biography
Dr. Miguel is currently Professor & Chair of Child and Adolescent Psychiatry, Department of Psychiatry, University of São Paulo School of Medicine (USP). Through a network of professional associations established in the last decades, Eurípedes Miguel set up productive partnerships with the major university centers in the world, recently being appointed Adjunct Associate Professor of the Department of Psychiatry and Behavioral Sciences of the Duke University Medical Center, Adjunct Associate Professor of the Yale Child Study Center, Yale University School of Medicine and Consultant in Research at the Massachusetts General Hospital, Harvard Medical School. He was the founder and coordinator of the Obsessive-Compulsive Spectrum Disorders Program of the Institute of Psychiatry at USP (1994-2009) and is now the Coordinator of the National Institute for Developmental Psychiatry (www.inpd.org.br) focused on preventive measures for Children and Adolescents.
Appointments
Child Study Center
Associate Professor AdjunctPrimary
Other Departments & Organizations
Education & Training
- PhD
- Harvard Medical School, Massachusetts General Hospital (1994)
- PhD
- University of São Paulo, Psychiatry Department (1992)
- MD
- University of Sao Paulo Medical School (1982)
Research
Overview
- Comorbidities Trajectory in Obsessive-Compulsive Disorder
- Neural Circuits and Biological Markers Involved in Obsessive-Compulsive Behavior by Paradigms of Fear and Anxiety
- National Institute of Science and Technology Developmental Psychiatry for Children and adolescents
- A Multicenter Sequential Multiple Assignment Randomized Trial (SMART) for children with OCD
- Scholar High risk cohort study for the development of psychopathology and resilience – PREVENTION Study
- Butantã (SP) Birth Cohort
- Pregnant Women Cohort Study
Medical Subject Headings (MeSH)
Psychiatry and Psychology
ORCID
0000-0002-9393-3103
Research at a Glance
Yale Co-Authors
Frequent collaborators of Euripedes C. Miguel's published research.
Publications Timeline
A big-picture view of Euripedes C. Miguel's research output by year.
James Leckman, MD, PhD
Thomas Fernandez, MD
Michael Bloch, MD, MS
Christopher Pittenger, MD, PhD
Michael Stevens, PhD
Paul Lombroso, MD
494Publications
16,909Citations
Publications
2024
Association Between Juvenile Psychotic Experiences and Problematic Gaming
Fernandes A, Biokino R, Miguel A, Machado V, Koga G, Fonseca L, Pan P, Roza T, Salum G, Passos I, Rohde L, Miguel E, Ziebold C, Gadelha A. Association Between Juvenile Psychotic Experiences and Problematic Gaming. Schizophrenia Bulletin Open 2024, 5: sgae021. PMID: 39296676, PMCID: PMC11408271, DOI: 10.1093/schizbullopen/sgae021.Peer-Reviewed Original ResearchConceptsPsychotic experiencesProblematic gamingGame addictionDSM-IVBrazilian community sampleDSM-IV diagnosisMental health conditionsCommunity samplePsychiatric disordersCross-sectional subsamplePsychiatric conditionsAssociated with significant adverse outcomesReport PEBehavioral pathwaysLevels of PESignificant adverse outcomesAssociated with PEPE scoresSociodemographic variablesAdverse outcomesBrazilian cohortDisordersParticipantsHealth conditionsLinear regression analysisAssociations between a Brazilian suicide awareness campaign and suicide trends from 2000 to 2019: Joinpoint and regression discontinuity analysis
Damiano R, Beiram L, Damiano B, Hoffmann M, Moreira-Almeida A, Rück C, Tavares H, Brunoni A, Miguel E, Menezes P, Salum G. Associations between a Brazilian suicide awareness campaign and suicide trends from 2000 to 2019: Joinpoint and regression discontinuity analysis. Journal Of Affective Disorders 2024, 365: 459-465. PMID: 39187205, DOI: 10.1016/j.jad.2024.08.134.Peer-Reviewed Original ResearchAltmetricConceptsJoinpoint analysisRegression discontinuity analysisAwareness campaignsLow-and-middle-income countriesSuicide trendsNational awareness campaignDiscontinuity analysisOfficial notification systemRates of suicidePublic awareness campaignsReduction interventionsGlobal health concernPotential unintended effectsCausative implicationAssess trendsEconomic factorsHealth concernMaternal immune response during pregnancy and neurodevelopmental outcomes: A longitudinal approach
Euclydes V, Braga C, Gouveia G, Martinez R, Camilo C, Simões S, Martins-Jr D, Fracolli L, Argeu A, Ferraro A, Matijasevich A, Fatori D, Miguel E, Polanczyk G, Brentani H. Maternal immune response during pregnancy and neurodevelopmental outcomes: A longitudinal approach. Brain Behavior & Immunity - Health 2024, 40: 100832. PMID: 39193418, PMCID: PMC11347843, DOI: 10.1016/j.bbih.2024.100832.Peer-Reviewed Original ResearchAltmetricConceptsMaternal immune responseTrimester of pregnancyImmune responseNeurodevelopmental outcomesImmunological markersImmunological biomarkersMaternal childhood traumaNeurodevelopmental trajectoriesMother's immune responseEarly stages of pregnancyWeeks of pregnancyMaternal psychosocial stressStages of pregnancyStages of gestationRandomized clinical trialsAnti-inflammatory stateMaternal stress experienceNeurodevelopmental scoresImmune system responseInflammatory biomarkersClinical trialsPregnancyPsychosocial stress conditionBlood samplesLinear mixed-effects modelsThe trajectory of anxiety symptoms during the transition from childhood to young adulthood is predicted by IQ and sex, but not polygenic risk scores
Salto A, Salum G, Hoffmann M, Santoro M, Zugman A, Pan P, Belangero S, Ito L, Doretto V, Croci M, Brañas M, de Giusti C, Da Silva‐Jr F, Ribeiro S, Miguel E, Leckman J. The trajectory of anxiety symptoms during the transition from childhood to young adulthood is predicted by IQ and sex, but not polygenic risk scores. JCPP Advances 2024 DOI: 10.1002/jcv2.12268.Peer-Reviewed Original ResearchAltmetricConceptsAnxiety symptomsIntelligence quotientTrajectory class membershipPolygenic risk scoresTrajectory classesLate adolescenceCourse of anxiety symptomsScreen for Child Anxiety Related DisordersTrajectories of anxiety symptomsBrazilian High-Risk CohortYoung adulthoodEffect of intelligence quotientAnxiety related disordersHigh-decreasing classClass membershipLongitudinal studyConfirmatory factor analysisGrowth mixture modelingIncidence of anxiety symptomsInternalizing symptomatologyLow-increasing classHigher IQCognitive abilitiesAnxiety riskFactor analysisGPT-based normative models of brain sMRI correlate with dimensional psychopathology
Mendes S, Pinaya W, Pan P, Gadelha A, Belangero S, Jackowski A, Rohde L, Miguel E, Sato J. GPT-based normative models of brain sMRI correlate with dimensional psychopathology. Imaging Neuroscience 2024, 2: 1-15. DOI: 10.1162/imag_a_00204.Peer-Reviewed Original ResearchAltmetricConceptsAttention deficit hyperactivity disorderChild Behavior ChecklistDeficit hyperactivity disorderAutism spectrum disorderPsychiatric disordersBrain regionsStructural MRIDimensional psychopathologyHyperactivity disorderBrazilian High-Risk Cohort StudyAttention deficit hyperactivity disorder scoresAutism Brain Imaging Data Exchange IIAdolescent Brain Cognitive DevelopmentChild Behavior Checklist scalesHigh Risk Cohort StudyDetect psychiatric symptomsEmergent psychiatric disordersBrain structural MRINeurobiological substratesNeuroimaging studiesLanguage tasksPsychiatric symptomsBehavior ChecklistPsychiatric conditionsSpectrum disorderIs waiting for rewards good for you? No association between impulsive choice, psychopathology, and functional outcomes in a large cohort sample
Bado P, Salum G, Rohde L, Gadelha A, Pan P, Miguel E, Tripp G, Furukawa E. Is waiting for rewards good for you? No association between impulsive choice, psychopathology, and functional outcomes in a large cohort sample. JCPP Advances 2024, 4: e12231. PMID: 38827985, PMCID: PMC11143955, DOI: 10.1002/jcv2.12231.Peer-Reviewed Original ResearchAltmetricConceptsDelayed rewardsPsychiatric conditionsPresence of psychiatric disordersLife outcomesBaseline task performanceImpulsive choicePositive long-term outcomesImmediate rewardsPsychiatric disordersTask performanceADHDResults ChildrenRewardChildren's preferencesStronger preferenceSchool-based cohortDisordersLongitudinal outcomesCohort sampleFunctional outcomesChildrenCohort of Brazilian childrenBrazilian childrenPsychopathologyDiverse populationsAn evaluation of treatment response and remission definitions in adult obsessive-compulsive disorder: A systematic review and individual-patient data meta-analysis
Ramakrishnan D, Farhat L, Vattimo E, Levine J, Johnson J, Artukoglu B, Landeros-Weisenberger A, Zangen A, Pelissolo A, de B Pereira C, Rück C, Costa D, Mataix-Cols D, Shannahoff-Khalsa D, Tolin D, Zarean E, Meyer E, Hawken E, Storch E, Andersson E, Miguel E, Maina G, Leckman J, Sarris J, March J, Diniz J, Kobak K, Mallet L, Vulink N, Amiaz R, Fernandes R, Shavitt R, Wilhelm S, Golshan S, Tezenas du Montcel S, Erzegovesi S, Baruah U, Greenberg W, Kobayashi Y, Bloch M. An evaluation of treatment response and remission definitions in adult obsessive-compulsive disorder: A systematic review and individual-patient data meta-analysis. Journal Of Psychiatric Research 2024, 173: 387-397. PMID: 38598877, DOI: 10.1016/j.jpsychires.2024.03.044.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsYale-Brown Obsessive-Compulsive ScaleObsessive-compulsive disorderCGI-IRandomized-controlled trialsAdult obsessive-compulsive disorderClinical Global Impression ImprovementObsessive-Compulsive ScaleTreatment responseIndividual-patient data meta-analysisPosttreatment scoresEvaluation of treatment responseMeta-analysis of randomized-controlled trialsFirst-line therapyCGIIndividual participant dataMeta-analysisNovel treatment modalitiesExpert consensusIndividual participant data meta-analysisSystematic reviewDisordersData meta-analysisPosttreatmentRemission definitionsImpressive improvementCausal Pathways Between the Acute Experience of Violence During Pregnancy and Fetal Intrauterine Growth Restriction: A Cohort Study
Blumrich L, Silva L, Barreto V, Rohde L, Polanczyk G, Miguel E, Grisi S, Fleitlich-Bilyk B, Ferraro A. Causal Pathways Between the Acute Experience of Violence During Pregnancy and Fetal Intrauterine Growth Restriction: A Cohort Study. Journal Of Women's Health 2024, 33: 765-773. PMID: 38551182, DOI: 10.1089/jwh.2023.0645.Peer-Reviewed Original ResearchConceptsIntrauterine growth restrictionAssociated with intrauterine growth restrictionGrowth restrictionProspective population-based birth cohortCausal pathwaysFetal intrauterine growth restrictionPopulation-based birth cohortExperiences of violenceNegative health consequencesAcute experimentsHealth consequences of violenceEmergency careGestational depressionGestational trimesterLow birthweightBirth cohortAlcohol consumptionCohort studyBlood pressurePregnancyConsequences of violencePath analysis modelMediation analysisCohortAdequate fitIncreases in functional connectivity between the default mode network and sensorimotor network correlate with symptomatic improvement after transcranial direct current stimulation for obsessive-compulsive disorder
Echevarria M, Batistuzzo M, Silva R, Brunoni A, Sato J, Miguel E, Hoexter M, Shavitt R. Increases in functional connectivity between the default mode network and sensorimotor network correlate with symptomatic improvement after transcranial direct current stimulation for obsessive-compulsive disorder. Journal Of Affective Disorders 2024, 355: 175-183. PMID: 38548207, DOI: 10.1016/j.jad.2024.03.141.Peer-Reviewed Original ResearchAltmetricConceptsTranscranial direct current stimulationObsessive-compulsive disorderDirect current stimulationCurrent stimulationActive transcranial direct current stimulationSensorimotor networkOCD symptom dimensionsTreatment-resistant obsessive-compulsive disorderNeurobiological mechanisms of actionObsessive-compulsive disorder pathophysiologyWhole-brain connectivity analysisDaily tDCS sessionsSymptom improvementResting-state functional MRITDCS sessionsNon-invasive neuromodulation interventionsBrain stimulation interventionsFunctional connectivity changesAssociated with connectivityLeft deltoidSymptom dimensionsNeurobiological mechanismsLeft precuneusMode networkPre/postcentral gyriPerinatal and neonatal factors and mental disorders in children and adolescents: looking for the contributions of the early environment to common and dissociable aspects of psychopathology
Leusin F, Damiano R, Mendes L, Hoffmann M, Manfro A, Pan P, Gadelha A, de Jesus Mari J, Manfro G, Miguel E, Rohde L, Bressan R, Salum G. Perinatal and neonatal factors and mental disorders in children and adolescents: looking for the contributions of the early environment to common and dissociable aspects of psychopathology. European Child & Adolescent Psychiatry 2024, 1-11. PMID: 38519607, DOI: 10.1007/s00787-024-02402-0.Peer-Reviewed Original ResearchConceptsMental disordersPsychiatric disordersCo-occurrence of mental disordersPresence of mental disordersDomains of psychopathologyYears of age childrenModel psychiatric disordersPsychiatric disorder diagnosisOverall psychopathologyBifactor modelDisorder diagnosisPsychopathologyBehavioral assessmentP-factorEarly environmentLow level of maternal educationLevel of maternal educationLow socioeconomic statusDisordersNeonatal factorsPrimary caregiversAge childrenAssociated with male sexSocioeconomic statusMaternal education
Academic Achievements & Community Involvement
activity São Paulo University
Public ServiceProfessorDetailsProfessor of Psychiatry2009 - Presentactivity São Paulo University
Public ServiceChairpersonDetailsChairman on Department of Psychiatry of Medical School in São Paulo University.12/01/2009 - Presentactivity São Paulo University
Public ServiceProfessorDetailsProfessor of Psychiatry, Department of Psychiatry, University of São Paulo Medical School2009 - Presentactivity Developmental Psychiatry National Institute for Children and Adolescent
Professional OrganizationsPresidentDetailsPresident National Institute for Developmental Psychiatry01/12/2009 - Presentactivity Institute of Psychiatry
CommitteesMemberDetailsMember, Executive Committee of Institute of Psychiatry, University of São Paulo2009 - Present
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