Protein arginine methyltransferase 1 regulates herpes simplex virus replication through ICP27 RGG-box methylation
Yu J, Shin B, Park E, Yang S, Choi S, Kang M, Rho J. Protein arginine methyltransferase 1 regulates herpes simplex virus replication through ICP27 RGG-box methylation. Biochemical And Biophysical Research Communications 2009, 391: 322-328. PMID: 19913501, DOI: 10.1016/j.bbrc.2009.11.057.Peer-Reviewed Original ResearchConceptsProtein arginine methyltransferase 1ICP27 RGG boxProtein arginine methylationArginine methylationRGG boxHerpes simplex virus type 1Arginine residuesRNA-binding activityArginine substitution mutantsArginine methyltransferase 1Gene expression in vivoRNA metabolismMethylation sitesSubcellular localizationSubstitution mutantsCellular processesCellular regulationExpression in vivoHerpes simplex virus replicationArginine mutationPRMT inhibitorsICP27Methyltransferase 1Cytokine signalingCellular mediators