2021
PIK3CA mutation in a case of CTNNB1 mutant sinonasal glomangiopericytoma
Hong C, Khan M, Sukys J, Prasad M, Erson-Omay EZ, Vining E, Omay SB. PIK3CA mutation in a case of CTNNB1 mutant sinonasal glomangiopericytoma. Molecular Case Studies 2021, 8: mcs.a006120. PMID: 34667073, PMCID: PMC8744496, DOI: 10.1101/mcs.a006120.Peer-Reviewed Original ResearchConceptsCase of glomangiopericytomaWhole-exome sequencingInstitutional review board-approved protocolTargeted medical therapyUnderwent surgical resectionPI3K/Akt/mTORWnt/β-cateninAkt/mTORPrimary sinonasal tumorSurgical resectionClinicopathologic characteristicsMedical therapyRare tumorPIK3CA mutationsSinonasal tumorsGlomangiopericytomaTumorsΒ-cateninSomatic mutationsComprehensive genetic characterizationGenomic characterizationMutationsConcurrent dysregulationResectionSinonasal
2006
Evolution of Medical Management of Chronic Rhinosinusitis
Vining E. Evolution of Medical Management of Chronic Rhinosinusitis. Annals Of Otology Rhinology & Laryngology 2006, 115: 54-60. DOI: 10.1177/00034894061150s909.Peer-Reviewed Original ResearchChronic rhinosinusitisMedical therapySuccessful endoscopic sinus surgeryAppropriate medical therapyMajority of patientsParanasal sinus infectionEndoscopic sinus surgeryLong-term reliefPossible causative factorsLeukotriene modifiersAspirin intoleranceEndoscopic evaluationMucosal changesMedical managementMucociliary dysfunctionSinus infectionNasal decongestantsMucosal diseaseNasal irrigationSinus surgeryComplex pathophysiologySinus culturesChronic diseasesNonallergic inflammationAnatomic variationsEvolution of medical management of chronic rhinosinusitis.
Vining E. Evolution of medical management of chronic rhinosinusitis. Annals Of Otology, Rhinology And Laryngology. Supplement 2006, 196: 54-60. PMID: 17040019, DOI: 10.1177/00034894061150s909.Peer-Reviewed Original ResearchConceptsChronic rhinosinusitisMedical therapySuccessful endoscopic sinus surgeryAppropriate medical therapyMajority of patientsParanasal sinus infectionEndoscopic sinus surgeryLong-term reliefPossible causative factorsLeukotriene modifiersAspirin intoleranceEndoscopic evaluationMucosal changesMedical managementMucociliary dysfunctionSinus infectionNasal decongestantsMucosal diseaseNasal irrigationSinus surgeryComplex pathophysiologySinus culturesChronic diseasesNonallergic inflammationAnatomic variations