2014
Lyme Disease
Solomon C, Shapiro E. Lyme Disease. New England Journal Of Medicine 2014, 370: 1724-1731. PMID: 24785207, PMCID: PMC4487875, DOI: 10.1056/nejmcp1314325.Peer-Reviewed Original Research
2009
A RANDOMIZED, PLACEBO-CONTROLLED TRIAL OF REPEATED IV ANTIBIOTIC THERAPY FOR LYME ENCEPHALOPATHY PROLONGED LYME DISEASE TREATMENT: ENOUGH IS ENOUGH
Marques A, Shaw P, Schmid C, Steere A, Kaplan R, Hassett A, Shapiro E, Wormser G. A RANDOMIZED, PLACEBO-CONTROLLED TRIAL OF REPEATED IV ANTIBIOTIC THERAPY FOR LYME ENCEPHALOPATHY PROLONGED LYME DISEASE TREATMENT: ENOUGH IS ENOUGH. Neurology 2009, 72: 383-386. PMID: 19171842, DOI: 10.1212/01.wnl.0000343855.45704.7c.Peer-Reviewed Original Research
1998
Lyme Arthritis in Children: Clinical Epidemiology and Long-term Outcomes
Gerber M, Zemel L, Shapiro E. Lyme Arthritis in Children: Clinical Epidemiology and Long-term Outcomes. Pediatrics 1998, 102: 905-908. PMID: 9755263, DOI: 10.1542/peds.102.4.905.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAnti-Bacterial AgentsChildChild, PreschoolChronic DiseaseConnecticutFemaleFollow-Up StudiesHumansInfantLyme DiseaseMalePrognosisConceptsLong-term outcomesLyme arthritisAppropriate antimicrobial therapyAntimicrobial therapyClinical epidemiologyLyme diseaseMean white blood cell countWhite blood cell countNewington Children's HospitalCells/mm3Pediatric rheumatology clinicTime of diagnosisEarly Lyme diseaseErythrocyte sedimentation rateLong-term followOnset of symptomsBlood cell countStructured telephone interviewActive arthritisChronic arthritisRheumatology clinicArthroscopic synovectomyInitial diagnosisChildren's HospitalTelephone followLyme Disease
Shapiro E. Lyme Disease. Pediatrics In Review 1998, 19: 147-154. PMID: 9584524, DOI: 10.1542/pir.19-5-147.Peer-Reviewed Original Research
1996
Lyme Disease in Children in Southeastern Connecticut
Gerber M, Shapiro E, Burke G, Parcells V, Bell G. Lyme Disease in Children in Southeastern Connecticut. New England Journal Of Medicine 1996, 335: 1270-1274. PMID: 8857006, DOI: 10.1056/nejm199610243351703.Peer-Reviewed Original ResearchConceptsErythema migrans lesionsSingle erythema migrans lesionLyme diseaseErythema migransClinical manifestationsMultiple erythema migrans lesionsCommunity-based cohort studyFacial nerve palsyInitial clinical manifestationPrompt clinical responseEarly Lyme diseasePercent of childrenConventional antimicrobial therapyMultiple erythemaClinical responseCohort studyAseptic meningitisConsecutive patientsMedian ageProspective dataAntimicrobial therapyAntibody testNew episodesPatientsLesions
1986
PREDICTORS OF PERSISTENTLY POSITIVE BLOOD CULTURES IN CHILDREN WITH “OCCULT” SALMONELLA BACTEREMIA
Katz B, Shapiro E. PREDICTORS OF PERSISTENTLY POSITIVE BLOOD CULTURES IN CHILDREN WITH “OCCULT” SALMONELLA BACTEREMIA. The Pediatric Infectious Disease Journal 1986, 5: 713. PMID: 3797307, DOI: 10.1097/00006454-198611000-00029.Peer-Reviewed Original ResearchAnti-Bacterial AgentsChildChild, PreschoolFemaleHumansInfantMaleSalmonella InfectionsSepsisTime FactorsRisk factors for development of bacterial meningitis among children with occult bacteremia
Shapiro E, Aaron N, Wald E, Chiponis D. Risk factors for development of bacterial meningitis among children with occult bacteremia. The Journal Of Pediatrics 1986, 109: 15-19. PMID: 3088242, DOI: 10.1016/s0022-3476(86)80564-9.Peer-Reviewed Original ResearchConceptsOccult bacteremiaBacterial meningitisInfluenzae type bClinical characteristicsInitial visitLumbar punctureRisk factorsRelative riskHaemophilus influenzae type bYale-New Haven HospitalH. influenzae type bType BChildren's HospitalPossible confounding effectsMeningitisBacteremiaEstimates of riskS. pneumoniaeStreptococcus pneumoniaeLogistic regressionN. meningitidisNeisseria meningitidisHospitalChildrenRisk
1982
Prophylaxis for contacts of patients with meningococcal or Haemophilus influenzae type b disease
SHAPIRO E. Prophylaxis for contacts of patients with meningococcal or Haemophilus influenzae type b disease. The Pediatric Infectious Disease Journal 1982, 1: 132-138. PMID: 6757888, DOI: 10.1097/00006454-198203000-00015.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsRole of prophylaxisHaemophilus influenzae type b diseaseHaemophilus influenzae type bContacts of patientsCases of meningitisType b diseaseDiagnosis of meningitisInfluenzae type bB diseaseNonepidemic periodsProphylaxisPatientsNeisseria meningitidisPreventive measuresDiseaseType BMeningitisRecommendations of expertsFamily membersSecondary spreadRecent studiesClose contactCurrent understandingIllnessPhysicians