Reduction in the Risk of Vertical Transmission of HIV-1 Associated with Treatment of Pregnant Women with Orally Administered Zidovudine Alone
Simpson B, Shapiro E, Andiman W. Reduction in the Risk of Vertical Transmission of HIV-1 Associated with Treatment of Pregnant Women with Orally Administered Zidovudine Alone. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1997, 14: 145-152. PMID: 9052723, DOI: 10.1097/00042560-199702010-00007.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, OralAdolescentAdultAnti-HIV AgentsCD4 Lymphocyte CountCohort StudiesDelivery, ObstetricFemaleHIV InfectionsHIV-1HumansInfantInfant, NewbornInfectious Disease Transmission, VerticalLongitudinal StudiesOdds RatioPregnancyPregnancy Complications, InfectiousProspective StudiesRetrospective StudiesRisk FactorsZidovudineConceptsRisk of transmissionT-lymphocyte countsMode of deliveryVertical transmissionHIV-1Cell countT-cell countsProspective cohort studyRisk of motherRoutine prenatal careSubgroup of womenChild transmissionUntreated womenCohort studyUntreated mothersPregnant womenPrenatal careObservational studyCD4ZidovudineSignificant associationWomenMothersRiskSignificant reduction