2004
CNS metastases in breast cancer.
Lin NU, Bellon JR, Winer EP. CNS metastases in breast cancer. Journal Of Clinical Oncology 2004, 22: 3608-17. PMID: 15337811, DOI: 10.1200/jco.2004.01.175.Peer-Reviewed Original ResearchMeSH KeywordsBrain NeoplasmsBreast NeoplasmsCentral Nervous System NeoplasmsFemaleHumansMeningeal NeoplasmsPrognosisRisk FactorsSurvival RateConceptsWhole brain radiotherapyBreast cancerCNS metastasesStereotactic radiosurgeryProportion of patientsMetastatic breast cancerGroup of patientsSingle brain metastasisBrain metastasesCNS involvementMultiple metastasesNeurologic symptomsSystemic therapyMedical therapyAppropriate therapyCase seriesClinical presentationRandomized trialsRetrospective seriesCase reportSolid tumorsMetastasisPatientsCancerRoutine use
2003
Central nervous system metastases in women who receive trastuzumab‐based therapy for metastatic breast carcinoma
Bendell JC, Domchek SM, Burstein HJ, Harris L, Younger J, Kuter I, Bunnell C, Rue M, Gelman R, Winer E. Central nervous system metastases in women who receive trastuzumab‐based therapy for metastatic breast carcinoma. Cancer 2003, 97: 2972-2977. PMID: 12784331, DOI: 10.1002/cncr.11436.Peer-Reviewed Original ResearchConceptsPercent of patientsMetastatic breast carcinomaTrastuzumab-based therapyCentral nervous system metastasesCentral nervous system diseaseNervous system metastasesCNS diseaseNervous system diseasesBreast carcinomaBrain metastasesCNS metastasesLeptomeningeal involvementSystem diseasesDisease sitesMore brain metastasesParenchymal brain metastasesProgressive CNS diseaseFirst-line therapyTime of diagnosisMedian survival periodBlood-brain barrierNew treatment strategiesStable diseaseMetastatic diseasePharmacy records