2024
Second Primary Breast Cancer in Young Breast Cancer Survivors
Brantley K, Rosenberg S, Collins L, Ruddy K, Tamimi R, Schapira L, Borges V, Warner E, Come S, Zheng Y, Kirkner G, Snow C, Winer E, Partridge A. Second Primary Breast Cancer in Young Breast Cancer Survivors. JAMA Oncology 2024, 10: 718-725. PMID: 38602683, PMCID: PMC11009864, DOI: 10.1001/jamaoncol.2024.0286.Peer-Reviewed Original ResearchGenetic testingYoung Women's Breast Cancer StudyYoung breast cancer survivorsBreast cancerBreast cancer survivorsYoung BC survivorsPrimary breast cancerGermline genetic testingIII BCMedical record reviewBreast Cancer StudyGermline pathogenic variantsPathogenic variantsBC survivorsTreatment decision-makingCancer survivorsFine-Gray subdistribution hazard modelCumulative incidencePV carriersSubdistribution hazard modelStage 0Patient surveyCharacterize risk factorsUnilateral mastectomyPrimary BC
2007
Genetic testing in young women with breast cancer: Results from a web-based survey
Shin J, Gelber S, Garber J, Rosenberg R, Przypyszny M, Winer E, Partridge A. Genetic testing in young women with breast cancer: Results from a web-based survey. Journal Of Clinical Oncology 2007, 25: 21093-21093. DOI: 10.1200/jco.2007.25.18_suppl.21093.Peer-Reviewed Original ResearchBreast cancerOvarian cancerFamily historyGenetic testingYoung womenWeb-based surveyYoung breast cancer survivorsTime of diagnosisBreast cancer survivorsHigh-risk populationMajority of womenFear of recurrenceQuality of lifeCross-sectional surveyLarge web-based surveyBreast cancer diagnosisCancer survivorsBRCA1/2 mutationsAge 40Baseline anxietyNumber of childrenFertility issuesCancerMultivariate modelSignificant financial relationship
2003
Attitudes, knowledge, risk perceptions and decision‐making among women with breast and/or ovarian cancer considering testing for BRCA1 and BRCA2 and their spouses
Bluman LG, Rimer BK, Sterba K, Lancaster J, Clark S, Borstelmann N, Iglehart JD, Winer EP. Attitudes, knowledge, risk perceptions and decision‐making among women with breast and/or ovarian cancer considering testing for BRCA1 and BRCA2 and their spouses. Psycho-Oncology 2003, 12: 410-427. PMID: 12833555, DOI: 10.1002/pon.653.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedATP Binding Cassette Transporter, Subfamily G, Member 2ATP-Binding Cassette TransportersBRCA1 ProteinBRCA2 ProteinBreast NeoplasmsDecision MakingDNA Mutational AnalysisFemaleGenetic Predisposition to DiseaseGenetic TestingHealth Knowledge, Attitudes, PracticeHumansMaleMiddle AgedNeoplasm ProteinsNeoplasm Recurrence, LocalOvarian NeoplasmsRiskSpousesConceptsGenetic testingBreast cancer susceptibilityOvarian cancerBreast cancerCancer susceptibilityInvolvement of spousesWives' breast cancerBRCA2 mutationsBRCA2 testingFuture interventionsCancerWomenPersonal historyBRCA2Cancer geneticsOne-thirdBRCA1BreastSpousesInvolvementMost spousesDecision-making processTestingSusceptibilityMutations
2002
Pre-Counseling Education Materials for BRCA Testing: Does Tailoring Make a Difference?
Skinner CS, Schildkraut JM, Berry D, Calingaert B, Marcom PK, Sugarman J, Winer EP, Iglehart JD, Futreal PA, Rimer BK. Pre-Counseling Education Materials for BRCA Testing: Does Tailoring Make a Difference? Genetic Testing And Molecular Biomarkers 2002, 6: 93-105. PMID: 12215248, DOI: 10.1089/10906570260199348.Peer-Reviewed Original ResearchConceptsGenetic testingOvarian cancer susceptibilityTumor RegistryMean ageOvarian cancer gene BRCA1Ovarian cancerFamily historyMutation carriersBRCA testingBaseline surveyCancer susceptibilityEstimation of riskBehavioral targetsPrint materialsGreater improvementBreastFollowup surveyEducation materialsWomenGenes BRCA1Decision aidRiskBRCA1
2000
Patient Motivation, Satisfaction, and Coping in Genetic Counseling and Testing for BRCA1 and BRCA2
Clark S, Bluman L, Borstelmann N, Regan K, Winer E, Rimer B, Skinner C. Patient Motivation, Satisfaction, and Coping in Genetic Counseling and Testing for BRCA1 and BRCA2. Journal Of Genetic Counseling 2000, 9: 219-235. PMID: 26141318, DOI: 10.1023/a:1009463905057.Peer-Reviewed Original ResearchTesting for Hereditary Breast and Ovarian Cancer in the Southeastern United States
Miron A, Schildkraut J, Rimer B, Winer E, Skinner C, Futreal P, Culler D, Calingaert B, Clark S, Marcom P, Iglehart J. Testing for Hereditary Breast and Ovarian Cancer in the Southeastern United States. Annals Of Surgery 2000, 231: 624-634. PMID: 10767783, PMCID: PMC1421049, DOI: 10.1097/00000658-200005000-00002.Peer-Reviewed Original ResearchConceptsProphylactic surgeryPreventive surgeryOvarian cancerFree genetic testingProspective clinical trialsBreast cancer patientsHereditary breast cancerPositive test resultsUncertain clinical significanceMore heterogeneous populationsBaseline characteristicsCancer patientsBaseline questionnaireClinical trialsTime of entryBreast cancerClinical significanceHeterogeneous syndromeSurgeryHereditary breastNumber of womenDeleterious gene mutationsBRCA2 genesGenetic testingSpecial populations
1999
Attitudes, knowledge, and risk perceptions of women with breast and/or ovarian cancer considering testing for BRCA1 and BRCA2.
Bluman L, Rimer B, Berry D, Borstelmann N, Iglehart J, Regan K, Schildkraut J, Winer E. Attitudes, knowledge, and risk perceptions of women with breast and/or ovarian cancer considering testing for BRCA1 and BRCA2. Journal Of Clinical Oncology 1999, 17: 1040-6. PMID: 10071299, DOI: 10.1200/jco.1999.17.3.1040.Peer-Reviewed Original ResearchConceptsOvarian cancerBRCA2 mutationsHigh-risk womenPercent of womenBaseline questionnairePhysician referralCancer riskChallenges cliniciansGenetic testingKnowledge deficitsWomenCancerGene mutationsBreastBRCA2PatientsBaseline knowledgeRiskBRCA1Cancer geneticsTrialsRisk perceptionHigher proportionMutationsPerception of riskModeling Risk of Breast Cancer and Decisions about Genetic Testing
Parmigiani G, Berry D, Iversen E, Müller P, Schildkraut J, Winer E. Modeling Risk of Breast Cancer and Decisions about Genetic Testing. Lecture Notes In Statistics 1999, 140: 133-203. DOI: 10.1007/978-1-4612-1502-8_3.Peer-Reviewed Original ResearchBreast cancerFamily historyGenetic susceptibilityGenetic testingPreventive treatment decisionsPatient counselingRisk factorsTreatment decisionsClinical OncologyRelated cancersBRCA2 genesCancerMedical decision makingIndividualized informationRiskAccurate assessmentPatientsDuke UniversityRisk communicationBreastCliniciansEpidemiologyResearch UnitSusceptibilityOncology
1997
Genetic Testing for Susceptibility to Breast Cancer: Findings from Women's Focus Groups
Tessaro I, Borstelmann N, Regan K, Rimer B, Winer E. Genetic Testing for Susceptibility to Breast Cancer: Findings from Women's Focus Groups. Journal Of Women's Health 1997, 6: 317-327. PMID: 9201666, DOI: 10.1089/jwh.1997.6.317.Peer-Reviewed Original ResearchConceptsBreast cancerGenetic testingLoss of insuranceSupport needsPositive test resultsWomen's focus groupsFocus groupsUnaffected womenLifestyle changesMore public educationWomen's knowledgeMedical treatmentBRCA1 testingBRCA1 mutationsCancerWomenLifestyle choicesEffect of testingBalanced informationWomen's decisionsPhysiciansFamily membersFocus group discussionsSuch testingWomen's concernsA Review of Hereditary Breast Cancer: From Screening to Risk Factor Modification
Warmuth M, Sutton L, Winer E. A Review of Hereditary Breast Cancer: From Screening to Risk Factor Modification. The American Journal Of Medicine 1997, 102: 407-415. PMID: 9217624, DOI: 10.1016/s0002-9343(97)00093-4.Peer-Reviewed Original ResearchConceptsRisk factor modificationBreast cancerFactor modificationGenetic testingBreast cancer riskBreast cancer casesHereditary breast cancerPotential prophylactic measuresClinical managementBRCA2 mutationsCancer casesCancer riskProphylactic measuresWay patientsCancerGene mutationsGenetic mutationsGenetic testsGenetic aspectsMajor advancesBRCA1MutationsScreeningPatientsDisease