Augmentation of venlafaxine and selective serotonin reuptake inhibitors with zolpidem improves sleep and quality of life in breast cancer patients with hot flashes
Joffe H, Partridge A, Giobbie-Hurder A, Li X, Habin K, Goss P, Winer E, Garber J. Augmentation of venlafaxine and selective serotonin reuptake inhibitors with zolpidem improves sleep and quality of life in breast cancer patients with hot flashes. Menopause The Journal Of The North American Menopause Society 2010, 17: 908-916. PMID: 20581724, DOI: 10.1097/gme.0b013e3181dbee1b.Peer-Reviewed Original ResearchMeSH KeywordsAdultBreast NeoplasmsChemotherapy, AdjuvantCyclohexanolsDouble-Blind MethodDrug Therapy, CombinationFemaleHot FlashesHumansHypnotics and SedativesMiddle AgedPlacebosPyridinesQuality of LifeSelective Serotonin Reuptake InhibitorsSleep Disorders, IntrinsicVenlafaxine HydrochlorideZolpidemConceptsSerotonin-norepinephrine reuptake inhibitorsSelective serotonin reuptake inhibitorsQuality of lifeSSRIs/serotonin-norepinephrine reuptake inhibitorsSerotonin reuptake inhibitorsBreast cancer survivorsHot flashesReuptake inhibitorsCancer survivorsHypnotic agentsSSRI/SNRI therapySSRI/SNRI usersNighttime hot flashesAdjuvant endocrine therapyAssociated sleep disturbancesBreast cancer patientsProportion of respondersSubjective sleep qualitySNRI therapySNRI usersBlinded treatmentEndocrine therapyPlacebo augmentationVenlafaxine XRNocturnal awakenings