2008
Predictors of blood pressure response to intensified and fixed combination treatment of hypertension: The ACCOMPLISH Study
Kjeldsen SE, Jamerson KA, Bakris GL, Pitt B, Dahlöf B, Velazquez EJ, Gupte J, Staikos L, Hua TA, Shi V, Hester A, Tuomilehto J, Östergren J, Ibsen H, Weber M, Investigators F. Predictors of blood pressure response to intensified and fixed combination treatment of hypertension: The ACCOMPLISH Study. Blood Pressure 2008, 17: 7-17. PMID: 18568687, DOI: 10.1080/08037050801972857.Peer-Reviewed Original ResearchMeSH KeywordsAgedAmlodipineAntihypertensive AgentsBenzazepinesBlood PressureDose-Response Relationship, DrugDouble-Blind MethodDrug ResistanceDrug Therapy, CombinationFemaleFinlandHumansHydrochlorothiazideHypertensionMaleMiddle AgedMultivariate AnalysisPredictive Value of TestsRacial GroupsRisk AssessmentScandinavian and Nordic CountriesTreatment OutcomeUnited StatesConceptsBlood pressureBP controlCombination therapyBaseline predictorsBP valuesCombination treatmentAbsolute BP valuesMain baseline predictorsPrevious antihypertensive medicationsLipid-lowering therapyUncontrolled blood pressureBlood pressure responseLarge outcome trialsLipid-lowering drugsSystolic BP valuesLogistic regression modelsBlinded baselineUncontrolled hypertensionAntihypertensive medicationsCardiovascular eventsSevere hypertensionSystolic hypertensionThiazide useOutcome trialsOverall patients
2007
Baseline characteristics in the Avoiding Cardiovascular events through Combination therapy in Patients Living with Systolic Hypertension (ACCOMPLISH) trial: A hypertensive population at high cardiovascular risk
Weber MA, Bakris GL, Dahlöf B, Pitt B, Velazquez E, Gupte J, Lefkowitz M, Hester A, Shi V, Weir M, Kjeldsen S, Massie B, Nesbitt S, Ofili E, Jamerson K, Investigators F. Baseline characteristics in the Avoiding Cardiovascular events through Combination therapy in Patients Living with Systolic Hypertension (ACCOMPLISH) trial: A hypertensive population at high cardiovascular risk. Blood Pressure 2007, 16: 13-19. PMID: 17453747, DOI: 10.1080/08037050701217643.Peer-Reviewed Original ResearchConceptsBody mass indexHigh cardiovascular riskCardiovascular eventsHypertensive patientsCardiovascular riskDiabetes mellitusCombination therapyNon-fatal cardiovascular endpointsCoronary artery bypass graftMean body mass indexAnti-lipid therapyAvoiding Cardiovascular EventsOral diabetes therapyPrevious antihypertensive treatmentSystolic Hypertension (ACCOMPLISH) trialDouble-blind treatmentAcute coronary syndromeArtery bypass graftAntihypertensive combination therapyHistory of strokePercutaneous coronary interventionAnti-platelet agentsACCOMPLISH trialAntihypertensive treatmentCardiovascular morbidity