2019
Biomarker Profile of Left Atrial Myopathy in Heart Failure With Preserved Ejection Fraction: Insights From the RELAX Trial
Patel RB, Alenezi F, Sun JL, Alhanti B, Vaduganathan M, Oh JK, Redfield MM, Butler J, Hernandez AF, Velazquez EJ, Shah SJ. Biomarker Profile of Left Atrial Myopathy in Heart Failure With Preserved Ejection Fraction: Insights From the RELAX Trial. Journal Of Cardiac Failure 2019, 26: 270-275. PMID: 31857197, PMCID: PMC7078046, DOI: 10.1016/j.cardfail.2019.12.001.Peer-Reviewed Original ResearchConceptsLA reservoir strainLA myopathyHeart failureNT-proBNPEjection fractionLA reservoirReservoir strainLA strainN-terminal pro-B-type natriuretic peptidePro-B-type natriuretic peptideAtrial mechanical dysfunctionEjection Fraction trialLA contractile strainLower LA reservoirJugular venous pressurePoor clinical outcomePhosphodiesterase-5 inhibitionAssociation of LAAtrial myopathyBaseline echocardiogramRELAX trialNeurohormonal activationExercise capacityVenous pressureClinical outcomes
2017
Adverse Remodeling and Reverse Remodeling After Myocardial Infarction
Bhatt AS, Ambrosy AP, Velazquez EJ. Adverse Remodeling and Reverse Remodeling After Myocardial Infarction. Current Cardiology Reports 2017, 19: 71. PMID: 28660552, DOI: 10.1007/s11886-017-0876-4.Peer-Reviewed Original ResearchConceptsAdverse LV remodelingMyocardial infarctionLV remodelingAdverse remodelingNeurohormonal regulationLeft ventricleCurrent evidence-based therapiesPost-MI heart failurePoor clinical outcomeAdverse cardiac remodelingPost-MI settingDevice-based therapiesEvidence-based therapiesNeurohormonal blockadeEarly revascularizationPathophysiological considerationsHeart failureVentricular dyssynchronyClinical outcomesEjection fractionMultiple imaging modalitiesCardiac remodelingTreatment strategiesReviewThe purposeInfarction