2015
Temporal Trends in Disease Severity and Predicted Surgical Risk at the Time of Referral for Echocardiography in Patients Diagnosed with Aortic Stenosis
Ersboll M, Samad Z, Al Enezi F, Kisslo J, Schulte PJ, Shaw LK, Køber L, Harrison JK, Bashore T, Brennan M, Velazquez EJ. Temporal Trends in Disease Severity and Predicted Surgical Risk at the Time of Referral for Echocardiography in Patients Diagnosed with Aortic Stenosis. Critical Pathways In Cardiology A Journal Of Evidence-Based Medicine 2015, 14: 103-109. PMID: 26214813, DOI: 10.1097/hpc.0000000000000048.Peer-Reviewed Original ResearchConceptsSevere aortic stenosisProportion of patientsAortic stenosisSurgical riskHigh-risk aortic valve replacementDisease severityHealth care resource planningAortic valve replacementCalcific aortic stenosisHeart valve surgeryTime of referralTertiary hospital centerNumber of patientsNative aortic valveDuke University HospitalLogistic EuroSCOREValve surgeryValve replacementMedian ageReferral patternsUniversity HospitalAortic valveHospital CenterPatientsReferral
2010
STICH (Surgical Treatment for Ischemic Heart Failure) Trial Enrollment
Jones RH, White H, Velazquez EJ, Shaw LK, Pietrobon R, Panza JA, Bonow RO, Sopko G, O'Connor CM, Rouleau JL. STICH (Surgical Treatment for Ischemic Heart Failure) Trial Enrollment. Journal Of The American College Of Cardiology 2010, 56: 490-498. PMID: 20670760, PMCID: PMC3259709, DOI: 10.1016/j.jacc.2009.11.102.Peer-Reviewed Original ResearchConceptsLow-risk patientsSTICH trialRAR groupBaseline characteristicsCardiac surgeryIschemic cardiomyopathyHigh-risk patientsNumber of patientsCountry of enrollmentSTICH patientsDuke DatabankRandomization groupTrial enrollmentCardiovascular diseaseRisk differencePatientsClinical decisionTrialsSurgeryCardiomyopathyRiskBroader populationEnrollment performanceDeathThirty-second
2009
Patients with prior coronary artery bypass grafting have a poor outcome after myocardial infarction: an analysis of the VALsartan in acute myocardial iNfarcTion trial (VALIANT)
Berry C, Pieper KS, White HD, Solomon SD, Van de Werf F, Velazquez EJ, Maggioni AP, Califf RM, Pfeffer MA, McMurray JJ. Patients with prior coronary artery bypass grafting have a poor outcome after myocardial infarction: an analysis of the VALsartan in acute myocardial iNfarcTion trial (VALIANT). European Heart Journal 2009, 30: 1450-1456. PMID: 19346225, DOI: 10.1093/eurheartj/ehp102.Peer-Reviewed Original ResearchConceptsPrior CABG patientsCoronary artery bypassMyocardial infarctionCABG patientsPrior CABGHeart failureArtery bypassNon-Q-wave myocardial infarctionPrior coronary artery bypassAcute Myocardial Infarction trialPrimary percutaneous coronary interventionKaplan-Meier ratesSecondary preventive therapyWorse clinical profileMyocardial Infarction trialVentricular systolic dysfunctionHigh-risk patientsPercutaneous coronary interventionAcute myocardial infarctionNumber of patientsNon-fatal outcomesHospital presentationLess aspirinMore comorbiditiesCardiovascular death
2006
Predicting significant coronary artery disease in patients with left ventricular dysfunction
Whellan DJ, Tuttle RH, Velazquez EJ, Shaw LK, Jollis JG, Ellis W, O'Connor CM, Califf RM, Borges-Neto S. Predicting significant coronary artery disease in patients with left ventricular dysfunction. American Heart Journal 2006, 152: 340-347. PMID: 16875920, DOI: 10.1016/j.ahj.2005.12.001.Peer-Reviewed Original ResearchConceptsSignificant coronary artery diseaseCoronary artery diseaseSegmental wall motion abnormalitiesLeft ventricular dysfunctionWall motion abnormalitiesEjection functionCardiac catheterizationVentricular dysfunctionArtery diseaseMedian ageMotion abnormalitiesLikelihood of CADAccurate baseline assessmentPatients' median ageMajor epicardial vesselsDiagnostic cardiac catheterizationNumber of patientsUnnecessary invasive proceduresStepwise logistic regressionClinical characteristicsEchocardiographic parametersPrevalent comorbiditiesDuke DatabankHeart failureDiabetes mellitus