2018
Crowdsourcing consensus: proposal of a novel method for assessing accuracy in echocardiography interpretation
Minter S, Armour A, Tinnemore A, Strub K, Crowley AL, Bloomfield GS, Alexander JH, Douglas PS, Kisslo JA, Velazquez EJ, Samad Z. Crowdsourcing consensus: proposal of a novel method for assessing accuracy in echocardiography interpretation. The International Journal Of Cardiovascular Imaging 2018, 34: 1725-1730. PMID: 30128849, DOI: 10.1007/s10554-018-1389-y.Peer-Reviewed Original ResearchConceptsStress echocardiography studyObstructive coronary diseaseGold standardWall motion abnormalitiesCoronary angiography dataCoronary diseaseStress echocardiographyEchocardiography studyHard outcomesMotion abnormalitiesStress echoSurvey participants' responsesClinical readsEchocardiographic interpretationImperfect gold standardIndependent consensusParticipants' responsesEchocardiographic imagesAngiography dataEchocardiography interpretationValidation surveyParticipantsEchocardiographyConsensusFirst survey
2015
Importance of Angina in Patients With Coronary Disease, Heart Failure, and Left Ventricular Systolic Dysfunction Insights From STICH
Jolicœur EM, Dunning A, Castelvecchio S, Dabrowski R, Waclawiw MA, Petrie MC, Stewart R, Jhund PS, Desvigne-Nickens P, Panza JA, Bonow RO, Sun B, San TR, Al-Khalidi HR, Rouleau JL, Velazquez EJ, Cleland JGF. Importance of Angina in Patients With Coronary Disease, Heart Failure, and Left Ventricular Systolic Dysfunction Insights From STICH. Journal Of The American College Of Cardiology 2015, 66: 2092-2100. PMID: 26541919, PMCID: PMC4655599, DOI: 10.1016/j.jacc.2015.08.882.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseLV systolic dysfunctionGreater survival benefitMedical therapySystolic dysfunctionCause mortalitySurvival benefitWorse prognosisCoronary artery bypass graft surgeryLeft ventricular systolic dysfunctionArtery bypass graft surgeryLong-term clinical outcomesGreater prognostic benefitBypass graft surgeryVentricular systolic dysfunctionEffect of CABGMultivariable CoxSTICH trialGraft surgeryPrognostic benefitArtery diseaseCoronary diseaseEjection fractionHeart failureClinical outcomes
2010
Impact of early surgery on survival of patients with severe mitral regurgitation
Samad Z, Kaul P, Shaw LK, Glower DD, Velazquez EJ, Douglas PS, Jollis JG. Impact of early surgery on survival of patients with severe mitral regurgitation. Heart 2010, 97: 221. PMID: 21071750, DOI: 10.1136/hrt.2010.202432.Peer-Reviewed Original ResearchConceptsSevere mitral regurgitationDegenerative mitral regurgitationEarly surgery groupLate surgery groupEarly surgeryMitral regurgitationSurgery groupLate surgeryGuideline indicationsOptimal timingValve diseaseMV repairAdjusted Cox regression modelCongenital mitral valve diseaseValve repair/replacementSevere degenerative mitral regurgitationACC/AHA guideline recommendationsSevere valve diseaseSurvival of patientsTiming of surgeryMitral valve diseaseCox regression modelLong-term survivalEarly referralCoronary diseaseDoes Myocardial Perfusion Imaging Provide Incremental Prognostic Information to Left Ventricular Ejection Fraction?
Mudrick DW, Velazquez E, Borges-Neto S. Does Myocardial Perfusion Imaging Provide Incremental Prognostic Information to Left Ventricular Ejection Fraction? Current Cardiology Reports 2010, 12: 155-161. PMID: 20425171, DOI: 10.1007/s11886-010-0093-x.Peer-Reviewed Original ResearchMeSH KeywordsCardiac-Gated Single-Photon Emission Computer-Assisted TomographyCoronary Artery DiseaseDeath, Sudden, CardiacHumansMass ScreeningMyocardial Perfusion ImagingPositron-Emission TomographyPredictive Value of TestsPrognosisRisk AssessmentSensitivity and SpecificityStroke VolumeVentricular Function, LeftConceptsEjection fractionVentricular functionNonfatal cardiac eventsGated single-photon emissionIncremental prognostic informationSignificant coronary diseaseVentricular ejection fractionCoronary artery diseaseOptimal treatment strategySudden cardiac deathNuclear imaging studiesImportant clinical implicationsMyocardial perfusion imagingPositron emission tomographySingle photon emissionIschemic burdenCardiac eventsArtery diseaseCardiac deathCoronary diseasePrognostic informationTreatment strategiesMyocardial perfusionPerfusion imagingBest predictor
2006
Contemporary performance of surgical ventricular restoration procedures: Data from the Society of Thoracic Surgeons' National Cardiac Database
Hernandez AF, Velazquez EJ, Dullum MK, O'Brien SM, Ferguson TB, Peterson ED. Contemporary performance of surgical ventricular restoration procedures: Data from the Society of Thoracic Surgeons' National Cardiac Database. American Heart Journal 2006, 152: 494-499. PMID: 16923420, DOI: 10.1016/j.ahj.2006.01.016.Peer-Reviewed Original ResearchConceptsSurgical ventricular restorationNational Cardiac DatabaseThoracic Surgeons National Cardiac DatabaseSVR procedureCardiac DatabaseSurgical ventricular restoration proceduresAdverse procedural outcomesVentricular restoration proceduresCombined end pointSevere mitral insufficiencyLeft ventricular dysfunctionCongestive heart failureInsulin-dependent diabetesStatus of surgeryCombined deathMajor morbidityOperative mortalityVentricular dysfunctionBaseline characteristicsOperative riskRenal failureCoronary diseaseHeart failureMajor complicationsOperative outcomes
2004
Usefulness of myocardial viability or ischemia in predicting long-term survival for patients with severe left ventricular dysfunction undergoing revascularization
Liao L, Cabell CH, Jollis JG, Velazquez EJ, Smith WT, Anstrom KJ, Pappas PA, Ryan T, Kisslo JA, Landolfo CK. Usefulness of myocardial viability or ischemia in predicting long-term survival for patients with severe left ventricular dysfunction undergoing revascularization. The American Journal Of Cardiology 2004, 93: 1275-1279. PMID: 15135703, DOI: 10.1016/j.amjcard.2004.01.071.Peer-Reviewed Original ResearchConceptsSevere left ventricular dysfunctionLeft ventricular dysfunctionVentricular dysfunctionDobutamine stress echocardiographySignificant survival advantageLong-term survivalCoronary diseaseStress echocardiographyViable myocardiumMyocardial viabilityPrognostic powerSurvival advantagePatientsRevascularizationDysfunctionEchocardiographyIschemiaMyocardiumDiseaseMonths
2002
Comparison of coronary artery bypass grafting versus medical therapy on long-term outcome in patients with ischemic cardiomyopathy (a 25-year experience from the Duke Cardiovascular Disease Databank)
O’Connor C, Velazquez EJ, Gardner LH, Smith PK, Newman MF, Landolfo KP, Lee KL, Califf RM, Jones RH. Comparison of coronary artery bypass grafting versus medical therapy on long-term outcome in patients with ischemic cardiomyopathy (a 25-year experience from the Duke Cardiovascular Disease Databank). The American Journal Of Cardiology 2002, 90: 101-107. PMID: 12106836, DOI: 10.1016/s0002-9149(02)02429-3.Peer-Reviewed Original ResearchMeSH KeywordsAgedCardiac CatheterizationComorbidityCoronary AngiographyCoronary Artery BypassCoronary Artery DiseaseDisease-Free SurvivalFemaleFollow-Up StudiesHeart FailureHumansMaleMiddle AgedOutcome and Process Assessment, Health CareSurvival AnalysisTimeTreatment OutcomeVentricular Dysfunction, LeftConceptsCoronary artery bypass surgeryLong-term outcomesMedical therapyCoronary diseaseIschemic cardiomyopathyNew York Heart Association class IILeft ventricular ejection fractionCox proportional hazards modelDuke University Medical CenterDays of catheterizationInitial cardiac catheterizationMedical therapy armObservational treatment comparisonsCoronary artery bypassHeart failure symptomsMedical therapy groupVentricular systolic dysfunctionArtery bypass surgeryVentricular ejection fractionCoronary artery diseaseEpicardial coronary vesselsProportional hazards modelUniversity Medical CenterCABG groupTherapy arm