2016
Haptoglobin 2-2 Genotype Is Associated With Cerebral Salt Wasting Syndrome in Aneurysmal Subarachnoid Hemorrhage
Murthy S, Caplan J, Levy A, Pradilla G, Moradiya Y, Schneider E, Shalom H, Ziai W, Tamargo R, Nyquist P. Haptoglobin 2-2 Genotype Is Associated With Cerebral Salt Wasting Syndrome in Aneurysmal Subarachnoid Hemorrhage. Neurosurgery 2016, 78: 71-76. PMID: 26348010, DOI: 10.1227/neu.0000000000001000.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBiomarkersFemaleGenetic Association StudiesGenotypeHaptoglobinsHumansInappropriate ADH SyndromeMaleMiddle AgedProspective StudiesSubarachnoid HemorrhageConceptsAneurysmal subarachnoid hemorrhageCerebral infarctionSubarachnoid hemorrhageHp genotypeHp 2Cerebral Salt Wasting SyndromeGlasgow Outcome ScoreCerebral saltUrine sodiumBaseline characteristicsSymptomatic vasospasmIndependent predictorsUrine outputClinical outcomesOutcome scoresSubsequent vasospasmFunctional outcomeProspective confirmationMultivariate regression modelGenotype testingHaptoglobin 2Haptoglobin genotypeOutcome measuresHemorrhagePatients
2012
BRAF V600E mutation and Its Association with Clinicopathological Features of Papillary Thyroid Cancer: A Meta-Analysis
Li C, Lee K, Schneider E, Zeiger M. BRAF V600E mutation and Its Association with Clinicopathological Features of Papillary Thyroid Cancer: A Meta-Analysis. The Journal Of Clinical Endocrinology & Metabolism 2012, 97: 4559-4570. PMID: 23055546, PMCID: PMC3513529, DOI: 10.1210/jc.2012-2104.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAmino Acid SubstitutionCarcinomaCarcinoma, PapillaryFemaleGenetic Association StudiesGenetic Predisposition to DiseaseGlutamic AcidHumansLymphatic MetastasisMaleMutation, MissenseProto-Oncogene Proteins B-rafSex CharacteristicsThyroid Cancer, PapillaryThyroid NeoplasmsTumor BurdenValineConceptsLymph node metastasisPapillary thyroid cancerLymph node dissectionTall cell variant papillary thyroid cancerRoutine central lymph node dissectionCentral lymph node dissectionClassic papillary thyroid cancerNode dissectionBRAF V600E mutationClinicopathological featuresAbsence of capsuleTumor sizeMale genderOdds ratioThyroid cancerBRAF mutationsMantel-Haenszel pooled odds ratiosPresence of LNMV600E mutationStudy-specific odds ratiosManagement of patientsPooled odds ratioAggressive clinicopathological featuresImportant clinical decisionsConsecutive patients