2024
Heterogeneous gene expression during early arteriovenous fistula remodeling suggests that downregulation of metabolism predicts adaptive venous remodeling
Ohashi Y, Protack C, Aoyagi Y, Gonzalez L, Thaxton C, Zhang W, Kano M, Bai H, Yatsula B, Alves R, Hoshina K, Schneider E, Long X, Perry R, Dardik A. Heterogeneous gene expression during early arteriovenous fistula remodeling suggests that downregulation of metabolism predicts adaptive venous remodeling. Scientific Reports 2024, 14: 13287. PMID: 38858395, PMCID: PMC11164895, DOI: 10.1038/s41598-024-64075-8.Peer-Reviewed Original ResearchConceptsGene expression patternsArteriovenous fistula groupArteriovenous fistulaExpression patternsHeterogeneous gene expressionGene expression changesOutcomes of arteriovenous fistulaVenous remodelingArteriovenous fistula maturationPostoperative day 7Reduce patient morbidityRNA sequencingUpregulation of metabolismBioinformatics analysisGene expressionDownregulation of metabolismMetabolic pathwaysExpression changesGenesAVF maturationAVF remodelingFistula creationC57BL/6 miceClinical outcomesPatient morbidity
2013
Comparison of surgical bypass with angioplasty and stenting of superficial femoral artery disease
Malas M, Enwerem N, Qazi U, Brown B, Schneider E, Reifsnyder T, Freischlag J, Perler B. Comparison of surgical bypass with angioplasty and stenting of superficial femoral artery disease. Journal Of Vascular Surgery 2013, 59: 129-135. PMID: 23891488, DOI: 10.1016/j.jvs.2013.05.100.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, BalloonBaltimoreBlood Vessel Prosthesis ImplantationChi-Square DistributionFemaleFemoral ArteryHumansKaplan-Meier EstimateMaleMiddle AgedMultivariate AnalysisPeripheral Arterial DiseasePostoperative ComplicationsProportional Hazards ModelsRegistriesRisk FactorsStentsTime FactorsTreatment OutcomeVascular GraftingVascular PatencyVeinsConceptsPeripheral arterial diseaseFemoral-popliteal bypassPercutaneous transluminal angioplasty/stentingJohns Hopkins Bayview Medical CenterAngioplasty/stentingSuperficial femoral arteryReintervention rateTASC CSymptomatic patientsD lesionsMedical managementB lesionsFemoral arteryMedical CenterSuperficial femoral artery diseaseSymptomatic peripheral arterial diseaseFemoral artery diseaseTASC II ARate of reinterventionHigher reintervention rateBest treatment optionSimilar risk factorsProportional hazards modelTerms of patencyFisher's exact test