2024
Heterogeneous gene expression during early arteriovenous fistula remodeling suggests that downregulation of metabolism predicts adaptive venous remodeling
Ohashi Y, Protack C, Aoyagi Y, Gonzalez L, Thaxton C, Zhang W, Kano M, Bai H, Yatsula B, Alves R, Hoshina K, Schneider E, Long X, Perry R, Dardik A. Heterogeneous gene expression during early arteriovenous fistula remodeling suggests that downregulation of metabolism predicts adaptive venous remodeling. Scientific Reports 2024, 14: 13287. PMID: 38858395, PMCID: PMC11164895, DOI: 10.1038/s41598-024-64075-8.Peer-Reviewed Original ResearchConceptsGene expression patternsArteriovenous fistula groupArteriovenous fistulaExpression patternsHeterogeneous gene expressionGene expression changesOutcomes of arteriovenous fistulaVenous remodelingArteriovenous fistula maturationPostoperative day 7Reduce patient morbidityRNA sequencingUpregulation of metabolismBioinformatics analysisGene expressionDownregulation of metabolismMetabolic pathwaysExpression changesGenesAVF maturationAVF remodelingFistula creationC57BL/6 miceClinical outcomesPatient morbidity
2017
Financial Impact of Acute Kidney Injury After Cardiac Operations in the United States
Alshaikh H, Katz N, Gani F, Nagarajan N, Canner J, Kacker S, Najjar P, Higgins R, Schneider E. Financial Impact of Acute Kidney Injury After Cardiac Operations in the United States. The Annals Of Thoracic Surgery 2017, 105: 469-475. PMID: 29275828, DOI: 10.1016/j.athoracsur.2017.10.053.Peer-Reviewed Original ResearchConceptsAcute kidney injuryIndex hospitalization costsTotal index hospitalization costsIndex hospital costsCardiac operationsHospitalization costsKidney injuryDevelopment of AKISubstantial health care cost savingsClinical Modification diagnosis codesHealth care cost savingsMajor cardiac operationsCoronary artery bypassChronic renal failureNationwide Inpatient SampleMajor cardiac proceduresLong-term treatmentArtery bypassRenal failureValve replacementReplacement patientsAvoidable complicationsCardiac proceduresPatient morbidityDiagnosis codes