2016
Evaluation of the Effect of Diagnostic Molecular Testing on the Surgical Decision-Making Process for Patients With Thyroid Nodules
Noureldine S, Najafian A, Han P, Olson M, Genther D, Schneider E, Prescott J, Agrawal N, Mathur A, Zeiger M, Tufano R. Evaluation of the Effect of Diagnostic Molecular Testing on the Surgical Decision-Making Process for Patients With Thyroid Nodules. JAMA Otolaryngology - Head & Neck Surgery 2016, 142: 676-82. PMID: 27196108, DOI: 10.1001/jamaoto.2016.0850.Peer-Reviewed Original ResearchConceptsSurgical decision-making processMolecular testingSurgical consultationThyroid nodulesDiagnostic molecular testingEvidence of overtreatmentPertinent treatment optionsSurgical management algorithmRisk of malignancySurgical decision makingSurgical management planRadiological resultsStudy cohortSurgical managementTreatment algorithmProspective studyMean ageTreatment optionsMAIN OUTCOMEPatientsBethesda SystemHistopathology diagnosisControl groupCytopathology classificationHistopathology analysis
2015
Diagnostic Frequency Ratios Are Insufficient to Measure Laboratory Precision with The Bethesda System for Reporting Thyroid Cytopathology
Fazeli R, Schneider EB, Ali SZ, Zeiger MA, Olson MT. Diagnostic Frequency Ratios Are Insufficient to Measure Laboratory Precision with The Bethesda System for Reporting Thyroid Cytopathology. Acta Cytologica 2015, 59: 225-232. PMID: 26022342, DOI: 10.1159/000379738.Peer-Reviewed Original Research
2014
Malignancy risk and reproducibility associated with atypia of undetermined significance on thyroid cytology
Mathur A, Najafian A, Schneider E, Zeiger M, Olson M. Malignancy risk and reproducibility associated with atypia of undetermined significance on thyroid cytology. Surgery 2014, 156: 1471-1476. PMID: 25218896, DOI: 10.1016/j.surg.2014.08.026.Peer-Reviewed Original ResearchConceptsMalignancy riskUndetermined significanceAvailable surgical pathologyDiagnosis of AUSTertiary care centerFocal nuclear atypiaFine-needle aspiration specimensHürthle cell neoplasmsOutside diagnosisMalignancy rateCare centerCell neoplasmsMorphologic predictorsHigh riskNuclear atypiaSurgical pathologyBethesda SystemAUS subcategoriesAspiration specimensGreater riskThyroid CytopathologyThyroid cytologyAtypiaDiagnosisAUS