2011
Direct Observation of the Myosin Va Recovery Stroke That Contributes to Unidirectional Stepping along Actin
Shiroguchi K, Chin HF, Hannemann DE, Muneyuki E, De La Cruz EM, Kinosita K. Direct Observation of the Myosin Va Recovery Stroke That Contributes to Unidirectional Stepping along Actin. PLOS Biology 2011, 9: e1001031. PMID: 21532738, PMCID: PMC3075224, DOI: 10.1371/journal.pbio.1001031.Peer-Reviewed Original Research
2010
A Myosin V Inhibitor Based on Privileged Chemical Scaffolds
Islam K, Chin HF, Olivares AO, Saunders LP, De La Cruz EM, Kapoor TM. A Myosin V Inhibitor Based on Privileged Chemical Scaffolds. Angewandte Chemie International Edition 2010, 49: 8484-8488. PMID: 20878825, PMCID: PMC3063097, DOI: 10.1002/anie.201004026.Peer-Reviewed Original ResearchRobust processivity of myosin V under off-axis loads
Oguchi Y, Mikhailenko SV, Ohki T, Olivares AO, De La Cruz EM, Ishiwata S. Robust processivity of myosin V under off-axis loads. Nature Chemical Biology 2010, 6: 300-305. PMID: 20228794, PMCID: PMC2917589, DOI: 10.1038/nchembio.322.Peer-Reviewed Original Research
2008
Load-dependent ADP binding to myosins V and VI: Implications for subunit coordination and function
Oguchi Y, Mikhailenko SV, Ohki T, Olivares AO, De La Cruz EM, Ishiwata S. Load-dependent ADP binding to myosins V and VI: Implications for subunit coordination and function. Proceedings Of The National Academy Of Sciences Of The United States Of America 2008, 105: 7714-7719. PMID: 18509050, PMCID: PMC2409399, DOI: 10.1073/pnas.0800564105.Peer-Reviewed Original Research
2006
The Tail Domain of Myosin Va Modulates Actin Binding to One Head
Olivares AO, Chang W, Mooseker MS, Hackney DD, De La Cruz EM. The Tail Domain of Myosin Va Modulates Actin Binding to One Head. Journal Of Biological Chemistry 2006, 281: 31326-31336. PMID: 16921171, DOI: 10.1074/jbc.m603898200.Peer-Reviewed Original Research
2005
Holding the reins on Myosin V
Olivares AO, De La Cruz EM. Holding the reins on Myosin V. Proceedings Of The National Academy Of Sciences Of The United States Of America 2005, 102: 13719-13720. PMID: 16172373, PMCID: PMC1236595, DOI: 10.1073/pnas.0507068102.Peer-Reviewed Original ResearchThermodynamics of Nucleotide Binding to Actomyosin V and VI: A Positive Heat Capacity Change Accompanies Strong ADP Binding †
Robblee JP, Cao W, Henn A, Hannemann DE, De La Cruz EM. Thermodynamics of Nucleotide Binding to Actomyosin V and VI: A Positive Heat Capacity Change Accompanies Strong ADP Binding †. Biochemistry 2005, 44: 10238-10249. PMID: 16042401, DOI: 10.1021/bi050232g.Peer-Reviewed Original ResearchMagnesium, ADP, and Actin Binding Linkage of Myosin V: Evidence for Multiple Myosin V−ADP and Actomyosin V−ADP States †
Hannemann DE, Cao W, Olivares AO, Robblee JP, De La Cruz EM. Magnesium, ADP, and Actin Binding Linkage of Myosin V: Evidence for Multiple Myosin V−ADP and Actomyosin V−ADP States †. Biochemistry 2005, 44: 8826-8840. PMID: 15952789, DOI: 10.1021/bi0473509.Peer-Reviewed Original Research
2004
Mechanochemical coupling of two substeps in a single myosin V motor
Uemura S, Higuchi H, Olivares AO, De La Cruz EM, Ishiwata S. Mechanochemical coupling of two substeps in a single myosin V motor. Nature Structural & Molecular Biology 2004, 11: 877-883. PMID: 15286720, DOI: 10.1038/nsmb806.Peer-Reviewed Original Research
2002
Kinetic Characterization of the Weak Binding States of Myosin V †
Yengo CM, De La Cruz EM, Safer D, Ostap EM, Sweeney HL. Kinetic Characterization of the Weak Binding States of Myosin V †. Biochemistry 2002, 41: 8508-8517. PMID: 12081502, DOI: 10.1021/bi015969u.Peer-Reviewed Original Research
2000
Actin and Light Chain Isoform Dependence of Myosin V Kinetics †
De La Cruz E, Wells A, Sweeney H, Ostap E. Actin and Light Chain Isoform Dependence of Myosin V Kinetics †. Biochemistry 2000, 39: 14196-14202. PMID: 11087368, DOI: 10.1021/bi001701b.Peer-Reviewed Original Research
1999
The kinetic mechanism of myosin V
De La Cruz E, Wells A, Rosenfeld S, Ostap E, Sweeney H. The kinetic mechanism of myosin V. Proceedings Of The National Academy Of Sciences Of The United States Of America 1999, 96: 13726-13731. PMID: 10570140, PMCID: PMC24132, DOI: 10.1073/pnas.96.24.13726.Peer-Reviewed Original Research