Mechanical Heterogeneity Favors Fragmentation of Strained Actin Filaments
De La Cruz EM, Martiel JL, Blanchoin L. Mechanical Heterogeneity Favors Fragmentation of Strained Actin Filaments. Biophysical Journal 2015, 108: 2270-2281. PMID: 25954884, PMCID: PMC4423049, DOI: 10.1016/j.bpj.2015.03.058.Peer-Reviewed Original ResearchConceptsMechanical propertiesFilament deformationEnergy densityElastic energyLocal shear forcesDeformation modesFilament strainFilament mechanical propertiesCompliant segmentsMechanical heterogeneityCompressive forceShear forceDeformationFree energy densityElastic free energy densityTwisting rigiditiesShape deformationLocal discontinuitiesSpatial confinementElasticitySevering efficiencyEnergyEnergy gradientConfinementForce