Quantitative Phenotyping of Xenopus Embryonic Heart Pathophysiology Using Hemoglobin Contrast Subtraction Angiography to Screen Human Cardiomyopathies
Deniz E, Jonas S, Khokha MK, Choma MA. Quantitative Phenotyping of Xenopus Embryonic Heart Pathophysiology Using Hemoglobin Contrast Subtraction Angiography to Screen Human Cardiomyopathies. Frontiers In Physiology 2019, 10: 1197. PMID: 31620018, PMCID: PMC6763566, DOI: 10.3389/fphys.2019.01197.Peer-Reviewed Original ResearchCongenital heart diseaseMyocardial functionSubtraction angiographyHuman cardiomyopathyEfficient animal modelMicroangiography techniqueCardiac dysfunctionCardiac lesionsUnderlying pathophysiologyCardiac functionHeart diseaseAnimal modelsSignificant causeHuman candidate genesHeart pathophysiologyPatientsAngiographyCardiomyopathyPathophysiologyBiomechanical phenotypeDysfunctionCandidate genesDiseaseGene dysfunctionHuman genomic analysis