2018
Fish Oil and Perioperative Bleeding
Akintoye E, Sethi P, Harris WS, Thompson PA, Marchioli R, Tavazzi L, Latini R, Pretorius M, Brown NJ, Libby P, Mozaffarian D. Fish Oil and Perioperative Bleeding. Circulation Cardiovascular Quality And Outcomes 2018, 11: e004584. PMID: 30571332, PMCID: PMC6376981, DOI: 10.1161/circoutcomes.118.004584.Peer-Reviewed Original ResearchConceptsBleeding Academic Research Consortium bleedingPerioperative bleedingFish oil supplementationFish oil groupLower riskPrimary outcomeFish oilMean ageOil supplementationOil groupBleeding Academic Research ConsortiumPlasma phospholipid omega-3Coronary artery bypass graftMajor perioperative bleedingChest tube outputPlacebo-controlled trialAcademic Research ConsortiumArtery bypass graftTreatment of hypertriglyceridemiaAbsolute risk differenceParticipants' mean ageHealth care professionalsFatty acid levelsBleeding definitionsHemostasis definition
2016
Effect of fish oil on monoepoxides derived from fatty acids during cardiac surgery 1 [S]
Akintoye E, Wu J, Hou T, Song X, Yang J, Hammock B, Mozaffarian D. Effect of fish oil on monoepoxides derived from fatty acids during cardiac surgery 1 [S]. Journal Of Lipid Research 2016, 57: 492-498. PMID: 26749073, PMCID: PMC4766998, DOI: 10.1194/jlr.p062398.Peer-Reviewed Original ResearchConceptsPostoperative day 2PUFA supplementationCardiac surgeryDay 2Plasma phospholipid EPAFish oilAcute tissue injuryLevels of EPAPhospholipid EPAPlacebo groupSurgery 1Fatty acidsTissue injurySerial measuresDegree of increaseAcute stressSurgeryPlaceboSupplementationMefAPUFA precursorsInflammationPatientsLevelsInjury