2024
Longitudinal Assessment of Left Atrial Remodeling in Patients With Chronic Severe Aortic Regurgitation
Akintoye E, El Dahdah J, Dabbagh M, Patel H, Badwan O, Braghieri L, Chedid El Helou M, Kassab J, Jellis C, Desai M, Rodriguez L, Grimm R, Roselli E, Griffin B, Popovic Z. Longitudinal Assessment of Left Atrial Remodeling in Patients With Chronic Severe Aortic Regurgitation. JACC Cardiovascular Imaging 2024, 17: 1133-1145. PMID: 38878040, DOI: 10.1016/j.jcmg.2024.04.007.Peer-Reviewed Original ResearchLeft atrial volume indexLeft atrial reservoir strainAortic regurgitationLV parametersAssociated with survival benefitMedian follow-up periodChronic severe aortic regurgitationLeft ventricular (LVShort-term follow-upOptimal discriminatory thresholdsSevere aortic regurgitationAtrial volume indexIncremental prognostic valueAtrial reservoir strainLeft atrial remodelingFollow-up periodAssociated with survivalPredicting adverse eventsReservoir strainSerial echocardiographySevere ARSurvival benefitLA remodelingLV remodelingPrognostic value
2022
Clinical, functional and prognostic implications of severe atrial dilation in secondary mitral regurgitation
Layoun H, Mentias A, Akintoye E, Matta M, Kanaan C, Daou R, Ramchand J, Burns D, Gillinov A, Bhattacharya S, Puri R, Collier P, Griffin B, Kapadia S, Harb S. Clinical, functional and prognostic implications of severe atrial dilation in secondary mitral regurgitation. Open Heart 2022, 9: e001996. PMID: 35383126, PMCID: PMC8984044, DOI: 10.1136/openhrt-2022-001996.Peer-Reviewed Original ResearchConceptsSecondary mitral regurgitationAtrial dilationMitral regurgitationPrognostic implicationsSevere left atrial dilationSevere secondary mitral regurgitationLA reservoir strainLeft atrial dilationLeft ventricle dysfunctionPoor prognostic indicatorMV interventionVentricle dysfunctionMore diabetesAdult patientsTransthoracic echocardiographyEjection fractionIndependent predictorsAtrial fibrillationReservoir strainWorse prognosisPrognostic indicatorMR severityBetter outcomesFunctional alterationsPatients