2023
Correction: Impact of chronic kidney disease on in-hospital mortality and clinical outcomes of catheter ablation of ventricular tachycardia: Insights from the national readmission database
Khalil M, Maraey A, Aglan A, Akintoye E, Salem M, Elzanaty A, Younes A, Saeyeldin A, Barbhaiya C, Shokr M. Correction: Impact of chronic kidney disease on in-hospital mortality and clinical outcomes of catheter ablation of ventricular tachycardia: Insights from the national readmission database. Journal Of Interventional Cardiac Electrophysiology 2023, 1-1. PMID: 37009939, DOI: 10.1007/s10840-023-01539-3.Peer-Reviewed Original Research
2022
Clinical outcomes and 30-day readmissions associated with high-output heart failure
Uddin M, Mir T, Briasoulis A, Akintoye E, Adegbala O, Shafi I, Qureshi W, Afonso L. Clinical outcomes and 30-day readmissions associated with high-output heart failure. Hellenic Journal Of Cardiology 2022, 69: 24-30. PMID: 36273803, DOI: 10.1016/j.hjc.2022.10.004.Peer-Reviewed Original ResearchConceptsHigh-output heart failureNational Readmission DatabaseHeart failureMyelodysplastic syndromeHealthcare costsUtilization Project National Readmission DatabaseLow systemic vascular resistanceReduced ejection fractionSystemic vascular resistanceHigh cardiac outputQuality's Healthcare CostSickle cell diseaseHospital mortalityNoncardiovascular disordersUnderdiagnosed typeCardiovascular complicationsMorbid obesityVascular resistanceHematological complicationsReadmission ratesEjection fractionPulmonary diseaseClinical outcomesCardiac outputDiagnostic codesImpact of chronic kidney disease on in-hospital mortality and clinical outcomes of catheter ablation of ventricular tachycardia: Insights from the national readmission database
Khalil M, Maraey A, Aglan A, Akintoye E, Salem M, Elzanaty A, Younes A, Saeyeldin A, Barbhaiya C, Shokr M. Impact of chronic kidney disease on in-hospital mortality and clinical outcomes of catheter ablation of ventricular tachycardia: Insights from the national readmission database. Journal Of Interventional Cardiac Electrophysiology 2022, 66: 323-331. PMID: 35314904, DOI: 10.1007/s10840-022-01187-z.Peer-Reviewed Original ResearchConceptsChronic kidney diseaseNational Readmission DatabaseClinical outcomesVentricular tachycardiaCatheter ablationKidney diseaseHospital mortalityVT ablationOdds ratioCorresponding diagnosis codesUnderwent catheter ablationAcute kidney injuryTotal hospital chargesWorse clinical outcomesMean lengthMultivariable regression analysisCKD groupConclusionIn patientsGroup patientsKidney injurySecondary outcomesHospital chargesDiagnosis codesClinical dataEffective treatment
2020
Incidence and clinical outcomes of bleeding complications and acute limb ischemia in STEMI and cardiogenic shock
Pahuja M, Ranka S, Chehab O, Mishra T, Akintoye E, Adegbala O, Yassin A, Ando T, Thayer K, Shah P, Kimmelstiel C, Salehi P, Kapur N. Incidence and clinical outcomes of bleeding complications and acute limb ischemia in STEMI and cardiogenic shock. Catheterization And Cardiovascular Interventions 2020, 97: 1129-1138. PMID: 32473083, PMCID: PMC8344361, DOI: 10.1002/ccd.29003.Peer-Reviewed Original ResearchConceptsST-segment elevation myocardial infarctionAcute limb ischemiaLength of stayCardiogenic shockCS-STEMIHospital mortalityVascular complicationsLimb ischemiaClinical outcomesManagement of CSPercutaneous ventricular assist deviceIntra-aortic balloon pumpPercutaneous mechanical circulatory supportRetrospective cohort studyElevation myocardial infarctionMechanical circulatory supportVentricular assist deviceU.S. national databaseTandem HeartMultiorgan failureCohort studyBalloon pumpCommon complicationMembrane oxygenationCirculatory supportTrends, Outcomes, and Readmissions Among Left Ventricular Assist Device Recipients with Acute Kidney Injury Requiring Hemodialysis.
Adegbala O, Olakanmi O, Akintoye E, Inampudi C, Pahuja M, Alvarez P, Briasoulis A. Trends, Outcomes, and Readmissions Among Left Ventricular Assist Device Recipients with Acute Kidney Injury Requiring Hemodialysis. ASAIO Journal 2020, 66: 507-512. PMID: 31192850, DOI: 10.1097/mat.0000000000001036.Peer-Reviewed Original ResearchConceptsAcute kidney injuryLength of stayHospital mortalityKidney injuryLVAD recipientsMaintenance hemodialysisLVAD implantationAcute Kidney Injury Requiring HemodialysisVentricular assist device implantationVentricular assist device recipientsNational Readmission DatabaseAssist device implantationReduced hospital costsHospital outcomesPostoperative bleedingHospital dischargeRenal functionDevice implantationDevice recipientsHemodialysis therapyHospital characteristicsHospital costsHemodialysisReadmissionPatientsAortic Valve Replacement for Severe Aortic Stenosis Before and During the Era of Transcatheter Aortic Valve Implantation
Akintoye E, Ando T, Sandio A, Adegbala O, Salih M, Zubairu J, Oseni A, Sistla P, Alqasrawi M, Egbe A, Mentias A, Afonso L, Briasoulis A, Panaich S, Desai M. Aortic Valve Replacement for Severe Aortic Stenosis Before and During the Era of Transcatheter Aortic Valve Implantation. The American Journal Of Cardiology 2020, 126: 73-81. PMID: 32336533, DOI: 10.1016/j.amjcard.2020.03.038.Peer-Reviewed Original ResearchConceptsSevere aortic stenosisAortic valve replacementNational Inpatient SampleTAVI eraAortic stenosisMean annual changeValve replacementFavorable short-term outcomesTranscatheter aortic valve replacementTranscatheter aortic valve implantationRate of AVRAcute kidney injuryRate of strokeAortic valve implantationShort-term outcomesRisk-adjusted ratesHospital mortalityPre-TAVIHospital outcomesKidney injuryHome dischargeHospital dischargePacemaker implantationValve implantationMedian lengthRural–Urban Disparities in Intracerebral Hemorrhage Mortality in the USA: Preliminary Findings from the National Inpatient Sample
Otite F, Akano E, Akintoye E, Khandelwal P, Malik A, Chaturvedi S, Rosand J. Rural–Urban Disparities in Intracerebral Hemorrhage Mortality in the USA: Preliminary Findings from the National Inpatient Sample. Neurocritical Care 2020, 32: 715-724. PMID: 32232726, PMCID: PMC7223184, DOI: 10.1007/s12028-020-00950-2.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAphasiaCerebral HemorrhageComorbidityCraniotomyDeglutition DisordersFemaleHealthcare DisparitiesHospital Bed CapacityHospital MortalityHospitals, RuralHospitals, UrbanHumansHydrocephalusMaleMiddle AgedRespiration, ArtificialRisk FactorsUnited StatesYoung AdultConceptsNational Inpatient SampleSex-adjusted mortalityUrban hospitalRural hospitalsICH patientsInpatient SampleJoinpoint regressionIntracerebral hemorrhage mortalityMultivariable-adjusted modelsOdds of mortalityIntracerebral hemorrhage patientsCases of ICHHospital deathHospital mortalityMultivariable adjustmentUrban patientsRural patientsStroke careHemorrhage patientsMedicare insuranceRural-urban disparitiesPatientsResultsFrom 2004HospitalMortality gap
2019
P4727Comparing in-hospital outcomes of transcatheter mitral valve repair vs surgical mitral valve repair in patients with pulmonary hypertension
Ahmed A, Adegbala O, Akintoye E, Alhatemi G, Aldiwani H, Yassin A, Khalid M, Mishra T, Ajam M, Abubakar H, Shokr M, Afonso L. P4727Comparing in-hospital outcomes of transcatheter mitral valve repair vs surgical mitral valve repair in patients with pulmonary hypertension. European Heart Journal 2019, 40: ehz745.1104. DOI: 10.1093/eurheartj/ehz745.1104.Peer-Reviewed Original ResearchSurgical mitral valve repairMitral valve repairTranscatheter mitral valve repairAbsolute standardized differencesValve repairTMVR groupPercutaneous interventionHigher Elixhauser comorbidity scoreStandardized morbidity ratio weightsChronic obstructive pulmonary diseaseNationwide Inpatient Sample databasePropensity scoreLow periprocedural complicationsAcute kidney injuryChronic renal failureCoronary artery bypassElixhauser comorbidity scorePulmonary hypertension patientsCongestive heart failureObstructive pulmonary diseasePrevious myocardial infarctionMedian hospital costsHospital mortalityPH patientsTMVR patientsP3603Impact of idiopathic thrombocytopenic purpura on clinical outcomes in patients with acute myocardial infarction
Chehab O, Pahuja M, Adegbala O, Akintoye E, Ramia P, Morsi R, Alrojolah L, Mishra T, Shokr M, Kanj A, Abdallah N, Tabaja H, Afonso L, Abidov A. P3603Impact of idiopathic thrombocytopenic purpura on clinical outcomes in patients with acute myocardial infarction. European Heart Journal 2019, 40: ehz745.0462. DOI: 10.1093/eurheartj/ehz745.0462.Peer-Reviewed Original ResearchIdiopathic thrombocytopenic purpuraAcute myocardial infarctionLength of stayLonger LOSNon-ITP patientsAcute ischemic strokeClinical outcomesHospital mortalitySecondary outcomesThrombocytopenic purpuraAMI patientsMyocardial infarctionACC/AHA/ESCUS National Inpatient Sample databaseNational Inpatient Sample databaseCardiovascular risk factorsPropensity-matched cohortLow platelet countManagement of patientsShort-term mortalityLong-term outcomesCoronary revascularization proceduresHospital complicationsMore comorbiditiesAnticoagulation therapyGender Differences in Outcomes After Implantation of Left Ventricular Assist Devices
Ahmed A, Adegbala O, Akintoye E, Inampudi C, Ajam M, Yassin A, Olawusi E, Shokr M, Alvarez P, Briasoulis A. Gender Differences in Outcomes After Implantation of Left Ventricular Assist Devices. The Annals Of Thoracic Surgery 2019, 109: 780-786. PMID: 31479642, DOI: 10.1016/j.athoracsur.2019.07.032.Peer-Reviewed Original ResearchConceptsLVAD implantationContinuous-flow LVADVentricular assist device implantationLeft ventricular assist deviceAcute kidney injuryAssist device implantationMost common complicationsExtracorporeal membrane oxygenationMedian hospitalization costNational Inpatient SamplePostoperative cardiac tamponadeLength of stayYears of ageVentricular assist deviceGender-specific differencesHospital mortalityPostoperative thromboembolismCardiac tamponadeHospital outcomesKidney injuryPeriprocedural complicationsPostoperative sepsisCommon complicationInpatient mortalityLVAD placementThe impact of safety‐net burden on in‐hospital outcomes after surgical aortic valve replacement
Ando T, Adegbala O, Akintoye E, Briasoulis A, Takagi H. The impact of safety‐net burden on in‐hospital outcomes after surgical aortic valve replacement. Journal Of Cardiac Surgery 2019, 34: 1178-1184. PMID: 31441545, DOI: 10.1111/jocs.14187.Peer-Reviewed Original ResearchConceptsSurgical aortic valve replacementSafety-net burdenAortic valve replacementSAVR outcomesValve replacementAcute kidney injuryMajor perioperative complicationsHospital-level characteristicsNationwide Inpatient SampleLength of staySafety-net hospitalNumber of admissionsHospital mortalityNonroutine dischargeValvular surgeryHospital outcomesHospital stayKidney injuryPerioperative complicationsDisadvantaged patientsInpatient SampleHospital costsUnadjusted modelsHospitalPatientsClinical Impact of Atrial Fibrillation on Short-Term Outcomes and In-Hospital Mortality in Patients with Takotsubo Syndrome: A Propensity-Matched National Study
Yassin A, Subahi A, Adegbala O, Abubakar H, Dawdy J, Mishra T, Akintoye E, Shereef H, Ghandour M, Alhusain R, Shokr M, Oviedo C, Afonso L. Clinical Impact of Atrial Fibrillation on Short-Term Outcomes and In-Hospital Mortality in Patients with Takotsubo Syndrome: A Propensity-Matched National Study. Cardiovascular Revascularization Medicine 2019, 21: 522-526. PMID: 31439442, DOI: 10.1016/j.carrev.2019.07.022.Peer-Reviewed Original ResearchConceptsCost of hospitalizationAtrial fibrillationHospital mortalityHospital complicationsVentricular arrhythmiasNational Inpatient Sample databasePropensity score-matched analysisMajor cardiac complicationsTakotsubo syndrome patientsIn-Hospital MortalityNon-routine dischargeAtrial fibrillation groupAtrial fibrillation patientsShort-term outcomesNational Inpatient SampleLength of stayPotential confounding factorsCardiac complicationsHospital stayFibrillation groupFibrillation patientsSecondary outcomesTakotsubo syndromePrimary outcomeCardiac arrestIn-Hospital Outcomes of ST-Segment Elevation Myocardial Infarction Complicated With Cardiogenic Shock at Safety-Net Hospitals in the United States (from the Nationwide Inpatient Sample)
Ando T, Akintoye E, Adegbala O, Ashraf S, Shokr M, Takagi H, Grines C, Afonso L, Briasoulis A. In-Hospital Outcomes of ST-Segment Elevation Myocardial Infarction Complicated With Cardiogenic Shock at Safety-Net Hospitals in the United States (from the Nationwide Inpatient Sample). The American Journal Of Cardiology 2019, 124: 485-490. PMID: 31213279, DOI: 10.1016/j.amjcard.2019.05.037.Peer-Reviewed Original ResearchMeSH KeywordsAge DistributionAgedAged, 80 and overArrhythmias, CardiacAssisted CirculationCoronary Artery BypassDatabases, FactualEthnicityFemaleHeart-Assist DevicesHospital MortalityHumansMaleMiddle AgedPercutaneous Coronary InterventionRenal DialysisSafety-net ProvidersShock, CardiogenicST Elevation Myocardial InfarctionStrokeThrombolytic TherapyUnited StatesConceptsSafety-net hospitalPercutaneous coronary interventionSTEMI-CSCardiogenic shockHospital mortalityCoronary interventionST-Segment Elevation Myocardial Infarction ComplicatedST-segment elevation myocardial infarctionAdministration of thrombolysisMyocardial Infarction ComplicatedCoronary artery bypassElevation myocardial infarctionMechanical circulatory supportNationwide Inpatient SampleNew dialysisArtery bypassHospital outcomesClinical outcomesCirculatory supportInpatient stayMedian lengthPoor outcomeFatal arrhythmiasInpatient SampleMyocardial infarctionIncidence and predictors of readmissions to non-index hospitals after transcatheter aortic valve replacement and the impact on in-hospital outcomes: From the nationwide readmission database
Ando T, Adegbala O, Villablanca P, Akintoye E, Ashraf S, Shokr M, Siddiqui F, Takagi H, Grines C, Afonso L, Briasoulis A. Incidence and predictors of readmissions to non-index hospitals after transcatheter aortic valve replacement and the impact on in-hospital outcomes: From the nationwide readmission database. International Journal Of Cardiology 2019, 292: 50-55. PMID: 31053244, DOI: 10.1016/j.ijcard.2019.04.056.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve replacementNon-index hospitalsNon-index hospital readmissionsNon-index readmissionsAortic valve replacementNationwide Readmissions DatabaseHospital mortalityIndex hospitalHospital outcomesValve replacementHospital readmissionEndovascular transcatheter aortic valve replacementMetropolitan non-teaching hospitalsMultivariable logistic regression analysisAcute kidney injuryPredictors of readmissionAcute myocardial infarctionLength of stayLogistic regression analysisNon-teaching hospitalsElective readmissionsTAVR recipientsKidney injuryPacemaker placementHealthcare utilizationTrends in the Incidence of In-Hospital Mortality, Cardiogenic Shock, and Utilization of Mechanical Circulatory Support Devices in Myocarditis (Analysis of National Inpatient Sample Data, 2005–2014)
Pahuja M, Adegbala O, Mishra T, Akintoye E, Chehab O, Mony S, Singh M, Ando T, Abubaker H, Yassin A, Subahi A, Shokr M, Ranka S, Briasoulis A, Kapur N, Burkhoff D, Afonso L. Trends in the Incidence of In-Hospital Mortality, Cardiogenic Shock, and Utilization of Mechanical Circulatory Support Devices in Myocarditis (Analysis of National Inpatient Sample Data, 2005–2014). Journal Of Cardiac Failure 2019, 25: 457-467. PMID: 31035007, DOI: 10.1016/j.cardfail.2019.04.012.Peer-Reviewed Original ResearchConceptsIncidence of CSCardiogenic shockMechanical circulatory supportHospital mortalityMCS devicesPercutaneous ventricular assist deviceNational Inpatient Sample databaseMechanical circulatory support devicesIncidence of myocarditisPercutaneous cardiopulmonary supportCases of myocarditisIn-Hospital MortalityExtracorporeal membrane oxygenationCirculatory support devicesVentricular assist deviceTandem HeartHemodynamic instabilityMultiple comorbiditiesCardiopulmonary supportEndomyocardial biopsyMembrane oxygenationTotal admissionsCirculatory supportPatient mortalityPoor prognosisTrends, Outcomes and Readmissions among Left Ventricular Assist Device Recipients with Acute Kidney Injury Requiring Hemodialysis: An Insight from the National Readmissions Database 2012-2014
Inampudi C, Adegbala O, Akintoye E, Alvarez P, Briasoulis A. Trends, Outcomes and Readmissions among Left Ventricular Assist Device Recipients with Acute Kidney Injury Requiring Hemodialysis: An Insight from the National Readmissions Database 2012-2014. The Journal Of Heart And Lung Transplantation 2019, 38: s348. DOI: 10.1016/j.healun.2019.01.882.Peer-Reviewed Original ResearchAcute kidney injuryLength of stayPost-operative bleedingLVAD implantationHospital mortalityMaintenance hemodialysisLVAD recipientsHospital costsAcute Kidney Injury Requiring HemodialysisVentricular assist device implantationVentricular assist device recipientsAnnual national ratesNational Readmission DatabaseAssist device implantationChronic kidney diseaseAcute kidneyIndex admissionHospital outcomesKidney injuryHospital dischargeRenal functionDevice implantationDevice recipientsKidney diseaseHemodialysis therapyCharacteristics and Outcomes of Patients with Cardiogenic Shock Complicated by Acute Kidney Injury Requiring Hemodialysis
Inampudi C, Adegbala O, Akintoye E, Alvarez P, Briasoulis A. Characteristics and Outcomes of Patients with Cardiogenic Shock Complicated by Acute Kidney Injury Requiring Hemodialysis. The Journal Of Heart And Lung Transplantation 2019, 38: s63. DOI: 10.1016/j.healun.2019.01.141.Peer-Reviewed Original ResearchLength of stayCardiogenic shockOutcomes of patientsHospital mortalityAcute Kidney Injury Requiring HemodialysisPre-existing chronic kidney diseasePropensity score-matched groupsHigher comorbidity burdenAcute kidney injuryChronic kidney diseaseRenal replacement therapyHospital-level characteristicsRenal venous pressureNational Inpatient SampleComorbidity burdenHospital morbidityHospital outcomesKidney injuryElixhauser scoreRenal functionBiventricular functionDiabetes mellitusRenal perfusionVenous pressureHospitalization costsCardiac Implantable Electronic Devices in Adults with Tetralogy of Fallot
Egbe A, Vallabhajosyula S, Akintoye E, Deshmukh A. Cardiac Implantable Electronic Devices in Adults with Tetralogy of Fallot. The American Journal Of Cardiology 2019, 123: 1999-2001. PMID: 30961908, DOI: 10.1016/j.amjcard.2019.03.010.Peer-Reviewed Original ResearchConceptsCardiac implantable electronic devicesImplantable electronic devicesNationwide/National Inpatient SampleInflation-adjusted hospitalization costsNational Inpatient Sample databaseCharlson Comorbidity IndexMean hospital lengthPopulation-based studyNational Inpatient SampleSudden cardiac deathTetralogy of FallotTime of implantationComorbidity indexHospital lengthHospital mortalityCardiac deathTOF repairRepaired tetralogyRetrospective reviewHospitalization costsCIED implantationInpatient SampleTOF populationAdmissionObserved temporal increaseCharacteristics and Outcomes of Patients With Cardiogenic Shock Utilizing Hemodialysis for Acute Kidney Injury
Adegbala O, Inampudi C, Adejumo A, Otuonye G, Akintoye E, Elsayed R, Williams K, Alvarez P, Afonso L, Briasoulis A. Characteristics and Outcomes of Patients With Cardiogenic Shock Utilizing Hemodialysis for Acute Kidney Injury. The American Journal Of Cardiology 2019, 123: 1816-1821. PMID: 30967283, DOI: 10.1016/j.amjcard.2019.02.038.Peer-Reviewed Original ResearchConceptsLength of stayAcute kidney injuryCardiogenic shockOutcomes of patientsHospital mortalityKidney injuryTemporary mechanical supportCause of CSPropensity score-matched groupsST-elevation myocardial infarctionMechanical circulatory support devicesHigher comorbidity burdenRenal replacement therapyElevation myocardial infarctionHospital-level characteristicsRenal venous pressureNational Inpatient SampleCirculatory support devicesComorbidity burdenHospital morbidityHospital outcomesRenal functionBiventricular functionRenal perfusionVenous pressureTrends in In-Hospital Mortality, Length of Stay, Nonroutine Discharge, and Cost Among End-Stage Renal Disease Patients on Dialysis Hospitalized With Heart Failure (2001–2014)
Inampudi C, Akintoye E, Bengaluru Jayanna M, Asleh R, Briasouli A, Alvarez P, Briasoulis A. Trends in In-Hospital Mortality, Length of Stay, Nonroutine Discharge, and Cost Among End-Stage Renal Disease Patients on Dialysis Hospitalized With Heart Failure (2001–2014). Journal Of Cardiac Failure 2019, 25: 524-533. PMID: 30844441, DOI: 10.1016/j.cardfail.2019.02.020.Peer-Reviewed Original ResearchConceptsLength of stayEnd-stage renal disease patientsHF admissionsRenal disease patientsHospital mortalityNonroutine dischargeHeart failureESRD patientsDisease patientsStudy periodAnnual national ratesHF admission ratesPrevalence of comorbiditiesIn-Hospital MortalityNational Inpatient SampleCost of hospitalizationAnnual percentage changeYears of ageHF hospitalizationSecondary admissionsAdmission diagnosisComorbidity prevalencePeritoneal dialysisSubgroup analysisInpatient Sample