Angiogenesis in peripheral arterial disease
Inampudi C, Akintoye E, Ando T, Briasoulis A. Angiogenesis in peripheral arterial disease. Current Opinion In Pharmacology 2018, 39: 60-67. PMID: 29529399, DOI: 10.1016/j.coph.2018.02.011.Peer-Reviewed Original ResearchConceptsPeripheral arterial diseaseCritical limb ischemiaVascular endothelial growth factorHepatocyte growth factorFibroblast growth factorGrowth factorArterial diseaseTherapeutic angiogenesisCell therapyNew arterial vesselsAnkle-brachial indexPreferred therapeutic strategyPrevention of amputationProgenitor cell therapyAdipose-derived progenitor cellsEndothelial growth factorStem cell therapyAngiogenic growth factorsClaudication symptomsAdvanced diseaseAmputation rateLimb ischemiaInvestigational therapiesUlcer healingPeripheral arteries