Studying Vascular Angiogenesis and Senescence in Zebrafish Embryos
Ristori E, Donnini S, Ziche M. Studying Vascular Angiogenesis and Senescence in Zebrafish Embryos. Methods In Molecular Biology 2016, 1430: 387-400. PMID: 27172969, DOI: 10.1007/978-1-4939-3628-1_27.Peer-Reviewed Original ResearchConceptsZebrafish embryosFluorescent transgenic linesCyclin-dependent kinase inhibitor p21 expressionVessel formationTransgenic linesSenescence defectsZebrafish modelPhosphatase activityAlkaline phosphatase activityEmbryosSenescenceExcellent animal modelExcellent disease modelZebrafishP21 expressionBrain degenerative changesNeurodegenerative diseasesVascular angiogenesisVascular senescenceΒ-galactosidaseOptical translucencyPeptide treatmentAmyloid β-peptideAngiogenesisDisease models