2023
Critical Care Management of Patients After Cardiac Arrest: A Scientific Statement From the American Heart Association and Neurocritical Care Society
Hirsch K, Abella B, Amorim E, Bader M, Barletta J, Berg K, Callaway C, Friberg H, Gilmore E, Greer D, Kern K, Livesay S, May T, Neumar R, Nolan J, Oddo M, Peberdy M, Poloyac S, Seder D, Taccone F, Uzendu A, Walsh B, Zimmerman J, Geocadin R, Society O. Critical Care Management of Patients After Cardiac Arrest: A Scientific Statement From the American Heart Association and Neurocritical Care Society. Circulation 2023, 149: e168-e200. PMID: 38014539, PMCID: PMC10775969, DOI: 10.1161/cir.0000000000001163.Peer-Reviewed Original ResearchMeSH KeywordsAmerican Heart AssociationCardiopulmonary ResuscitationCritical CareEmergency Medical ServicesHeart ArrestHumansConceptsCritical care managementCardiac arrestNeurocritical Care SocietyCare managementClinical studiesAmerican Heart Association Emergency Cardiovascular Care CommitteeHigh-quality clinical studiesExpert panel consensus statementHigh-certainty evidencePractice guideline recommendationsLow-certainty evidenceAmerican Heart AssociationExpert consensus panelHigh-quality studiesMultiple medical specialtiesGuideline recommendationsHeart AssociationAbsence of guidelinesConsensus statementPractice guidelinesConsensus panelCare CommitteePatientsAreas of uncertaintyOrgan systems
2019
Comparison of machine learning models for seizure prediction in hospitalized patients
Struck AF, Rodriguez‐Ruiz A, Osman G, Gilmore EJ, Haider HA, Dhakar MB, Schrettner M, Lee JW, Gaspard N, Hirsch LJ, Westover MB, Consortium C. Comparison of machine learning models for seizure prediction in hospitalized patients. Annals Of Clinical And Translational Neurology 2019, 6: 1239-1247. PMID: 31353866, PMCID: PMC6649418, DOI: 10.1002/acn3.50817.Peer-Reviewed Original ResearchConceptsLow-risk patientsNegative predictive valueEvaluation cohortContinuous EEGElastic net logistic regressionMulticenter databaseRisk stratificationSeizure riskPatientsPredictive valueComparable AUCSecondary analysisLogistic regressionCohortFirst hourSeizure predictionEEG recordingsEEGRisk calibrationLarge proportionSeizuresComplex neural networks
2017
Ictal-Interictal Continuum: When to Worry About the Continuous Electroencephalography Pattern
Cormier J, Maciel CB, Gilmore EJ. Ictal-Interictal Continuum: When to Worry About the Continuous Electroencephalography Pattern. Seminars In Respiratory And Critical Care Medicine 2017, 38: 793-806. PMID: 29262437, DOI: 10.1055/s-0037-1607987.Peer-Reviewed Original ResearchMeSH KeywordsBrain DiseasesBrain InjuriesComaCritical CareCritical IllnessElectroencephalographyHumansSeizuresStatus EpilepticusConceptsNonconvulsive status epilepticusIctal-interictal continuumNonconvulsive seizuresEEG patternsSecondary brain injuryContinuous electroencephalography monitoringCritical care physiciansClear clinical significanceIIC patternsIll patientsStatus epilepticusCare physiciansCEEG monitoringElectroencephalography monitoringSeizure riskBrain injuryGuideline statementsClinical dilemmaClinical significanceNeuronal stressClinical approachDefinitive guidelinesElectroencephalography patternsPotential associationEarly detection
2016
Review of the Utility of Prophylactic Anticonvulsant Use in Critically Ill Patients With Intracerebral Hemorrhage
Gilmore EJ, Maciel CB, Hirsch LJ, Sheth KN. Review of the Utility of Prophylactic Anticonvulsant Use in Critically Ill Patients With Intracerebral Hemorrhage. Stroke 2016, 47: 2666-2672. PMID: 27608820, DOI: 10.1161/strokeaha.116.012410.Peer-Reviewed Original ResearchCritical Care Management of Intracerebral Hemorrhage
Morawo AO, Gilmore EJ. Critical Care Management of Intracerebral Hemorrhage. Seminars In Neurology 2016, 36: 225-232. PMID: 27214697, DOI: 10.1055/s-0036-1581991.Peer-Reviewed Original ResearchConceptsManagement of ICHIntracerebral hemorrhageMedical complicationsCare managementNeurocritical care managementSecondary brain injuryCritical care managementForm of strokeRole of imagingCritical care settingSpontaneous intracerebral hemorrhageLife-sustaining therapyMajor healthcare concernRisk factorsBrain injuryClinical trialsIntracranial pressureCare settingsEarly withdrawalHemorrhageHealthcare concernComplicationsPrognosisMajor targetIntensive monitoring
2012
Acute Effects of Nimodipine on Cerebral Vasculature and Brain Metabolism in High Grade Subarachnoid Hemorrhage Patients
Choi HA, Ko SB, Chen H, Gilmore E, Carpenter AM, Lee D, Claassen J, Mayer SA, Schmidt JM, Lee K, Connelly ES, Paik M, Badjatia N. Acute Effects of Nimodipine on Cerebral Vasculature and Brain Metabolism in High Grade Subarachnoid Hemorrhage Patients. Neurocritical Care 2012, 16: 363-367. PMID: 22262041, DOI: 10.1007/s12028-012-9670-8.Peer-Reviewed Original ResearchConceptsPoor-grade subarachnoid hemorrhageOral nimodipineSubarachnoid hemorrhageMmHg decreasePoor-grade SAH patientsDoses of nimodipineAdministration of nimodipineAneurysmal subarachnoid hemorrhageSubarachnoid hemorrhage patientsRoutine clinical careAcute PhysiologicAdequate CBFNimodipine administrationOnly medicationHemorrhage patientsMultimodality monitoringSAH patientsVasopressor medicationsBrain metabolismAcute effectsObservational studyMetabolic effectsCerebral vasculatureClinical careNimodipine
2011
Prevention of Shivering During Therapeutic Temperature Modulation: The Columbia Anti-Shivering Protocol
Choi HA, Ko SB, Presciutti M, Fernandez L, Carpenter AM, Lesch C, Gilmore E, Malhotra R, Mayer SA, Lee K, Claassen J, Schmidt JM, Badjatia N. Prevention of Shivering During Therapeutic Temperature Modulation: The Columbia Anti-Shivering Protocol. Neurocritical Care 2011, 14: 389-394. PMID: 21210305, DOI: 10.1007/s12028-010-9474-7.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic alpha-2 Receptor AgonistsAdultAgedAnticonvulsantsConscious SedationCritical CareDexmedetomidineDose-Response Relationship, DrugFemaleFeverGlasgow Coma ScaleHeart ArrestHumansHypothermia, InducedIntensive Care UnitsIntracranial HypertensionMagnesium SulfateMaleMeperidineMiddle AgedMonitoring, PhysiologicNarcoticsNeuromuscular Nondepolarizing AgentsPropofolProspective StudiesShiveringVecuronium BromideConceptsPatient daysNeurological intensive care unitAnti-shivering agentsTherapeutic temperature modulationTotal patient daysPrevention of shiveringDoses of propofolIntensive care unitBaseline demographic informationNew clinical problemsInduced normothermiaMethodsAll patientsYounger patientsCare unitCumulative doseHigh riskClinical problemPatientsTemperature modulating devicesMore interventionsShiveringBaseline interventionDemographic informationFirst agentYoung men