Regulation of volume‐activated chloride channels by P‐glycoprotein: phosphorylation has the final say!
Idriss H, Hannun Y, Boulpaep E, Basavappa S. Regulation of volume‐activated chloride channels by P‐glycoprotein: phosphorylation has the final say! The Journal Of Physiology 2000, 524: 629-636. PMID: 10790147, PMCID: PMC2269906, DOI: 10.1111/j.1469-7793.2000.00629.x.Peer-Reviewed Original ResearchConceptsProtein kinase CReversible phosphorylationChloride channelsChloride channel activityPhosphorylation of PgpSuch phosphorylationMultiple phosphorylationVolume-activated chloride channelsTransmembrane transportersKinase CPhosphorylationInhibition of transportCell volume changesPossible regulationChannel activityP-glycoproteinPotential involvementSuch regulationRegulation functionRegulationUnrelated drugsPgpProteinTransportersOverexpression