2003
Calcium-dependent, swelling-activated K+ conductance in human neuroblastoma cells
Basavappa S, Mangel A, Boulpaep E. Calcium-dependent, swelling-activated K+ conductance in human neuroblastoma cells. Biochemical And Biophysical Research Communications 2003, 308: 759-763. PMID: 12927783, DOI: 10.1016/s0006-291x(03)01481-5.Peer-Reviewed Original ResearchConceptsHuman neuroblastoma cell line CHP-100CHP-100Regulatory volume decreaseCell-attached patch-clamp studiesFree extracellular solutionHuman neuroblastoma cellsSwelling-activated ClPatch-clamp studiesFura-2Extracellular osmolarityFree extracellularNeuroblastoma cellsMOsm/Hypoosmotic solutionCell swellingExtracellular solutionCl- channelsHypoosmotic stressPresent studyMost mammalian cellsEGTACellsVolume decreaseEffluxPrevious studies
1993
Endothelin increases [Ca2+]i in M-1 mouse cortical collecting duct cells by a dual mechanism
Korbmacher C, Boulpaep E, Giebisch G, Geibel J. Endothelin increases [Ca2+]i in M-1 mouse cortical collecting duct cells by a dual mechanism. American Journal Of Physiology 1993, 265: c349-c357. PMID: 8368264, DOI: 10.1152/ajpcell.1993.265.2.c349.Peer-Reviewed Original ResearchConceptsEndothelin-1Intracellular storesDuct cellsNifedipine-sensitive Ca2Intracellular calcium concentrationParticipation of Ca2Endothelin increaseFura-2Extracellular calciumExtracellular Ca2Arginine vasopressinIntracellular Ca2Calcium concentrationInitial Ca2Fluorescent imaging systemInitial exposurePlateau phaseMiceEntry mechanismDual mechanismCa2Second Ca2CellsNifedipineVasopressin