2020
Chapter 26 Modeling autism spectrum disorders in zebrafish
Dreosti E, Hoffman E, Rihel J. Chapter 26 Modeling autism spectrum disorders in zebrafish. 2020, 451-480. DOI: 10.1016/b978-0-12-817528-6.00026-7.ChaptersZebrafish modelGenetics of ASDGenome-wide association studiesHundreds of genesNervous system formComplex behavioral repertoireHuman neurodevelopmental disordersWhole-genome sequencingExcellent systemGenetic informationGenome sequencingAssociation studiesGenerate mutationsZebrafishUnique human traitsHuman traitsHuman biologyNeurodevelopmental disordersASD biologyGenetic alterationsRapid discoveryGenesBiologyBehavioral repertoireNeuronal processes
2018
Zebrafish Models of Neurodevelopmental Disorders: Past, Present, and Future
Sakai C, Ijaz S, Hoffman EJ. Zebrafish Models of Neurodevelopmental Disorders: Past, Present, and Future. Frontiers In Molecular Neuroscience 2018, 11: 294. PMID: 30210288, PMCID: PMC6123572, DOI: 10.3389/fnmol.2018.00294.Peer-Reviewed Original ResearchGene functionZebrafish modelCRISPR/Cas9 geneSmall-molecule suppressorTransparent embryosZebrafish systemHigh-throughput pharmacological screensNeurodevelopmental disordersGenetic manipulationCas9 geneBehavioral phenotypesLarge progenyFunctional analysisLarval stagesPharmacological screensZebrafishRisk genesGenesModel systemExternal developmentPhenotypeCircuit-level mechanismsBasic mechanismsNeural circuitsNervous system