Featured Publications
In the balance: No new diagnosis needed in addition to opioid use disorder to study harms associated with long‐term opioid therapy
Drexler K, Edens E, Trafton J, Compton W. In the balance: No new diagnosis needed in addition to opioid use disorder to study harms associated with long‐term opioid therapy. Addiction 2023, 119: 6-8. PMID: 37766392, DOI: 10.1111/add.16349.Peer-Reviewed Original ResearchWhat Role Should Psychiatrists Have in Responding to the Opioid Epidemic?
Muvvala SB, Edens EL, Petrakis IL. What Role Should Psychiatrists Have in Responding to the Opioid Epidemic? JAMA Psychiatry 2019, 76: 107-108. PMID: 30484813, DOI: 10.1001/jamapsychiatry.2018.3123.Peer-Reviewed Original ResearchA Facility-Wide Plan to Increase Access to Medication for Opioid Use Disorder in Primary Care and General Mental Health Settings.
Spelman JF, Edens EL, Maya S, Moore BA, Boggs A, MacLean RR, Ackland P, Becker WC, Lynch D, Garcia-Vassallo M, Burgo AL, Rosen MI, Gordon AJ. A Facility-Wide Plan to Increase Access to Medication for Opioid Use Disorder in Primary Care and General Mental Health Settings. Federal Practitioner 2021, 38: 460-464. PMID: 34733066, PMCID: PMC8560103, DOI: 10.12788/fp.0186.Peer-Reviewed Original ResearchVeterans Affairs Connecticut Healthcare SystemOpioid use disorderMOUD accessPrimary careTarget clinicsUse disordersGeneral mental health clinicsKey interventionsMental health clinicsMental health settingsGeneral mental health settingsHealth care practitionersQuality improvement effortsElectronic health recordsEligible patientsMOUD receiptPrescriber characteristicsBuprenorphine prescribersOpioid epidemicHealth clinicsMOUDCare practitionersHealth settingsNational VAElectronic consultationThe 14-year course of alcoholism in a community sample: Do men and women differ?
Edens EL, Glowinski AL, Grazier KL, Bucholz KK. The 14-year course of alcoholism in a community sample: Do men and women differ? Drug And Alcohol Dependence 2007, 93: 1-11. PMID: 17935914, PMCID: PMC2324065, DOI: 10.1016/j.drugalcdep.2007.08.013.Peer-Reviewed Original ResearchConceptsAlcohol abusePast-year DSM-IV alcohol dependenceDSM-III alcohol abuseDSM-IV AUD criteriaPast-year alcohol use disorderCommunity sampleHealth service useCase-control studyEpidemiologic Catchment Area studyDSM-III criteriaDSM-IV alcohol dependencePatterns of drinkingCatchment Area StudyAlcohol use disorderDSM-IV alcohol abuseCourse of alcoholismRisk drinkingService useUse disordersClinical relevanceHeavy drinkersLifetime ratesAlcohol dependenceUnaffected controlsAlcohol use behaviors
2022
Moral Injury in the Context of Substance Use Disorders: a Narrative Review
Van Denend J, Harris JI, Fuehrlein B, Edens EL. Moral Injury in the Context of Substance Use Disorders: a Narrative Review. Current Treatment Options In Psychiatry 2022, 9: 321-330. PMID: 36158584, PMCID: PMC9483387, DOI: 10.1007/s40501-022-00280-4.Peer-Reviewed Original ResearchSubstance use disordersMoral injurySubstance useUse disordersSubstance use contextsDopaminergic reward systemContext of SUDMilitary service membersSubstance use treatmentReward systemChronic medical conditionsDrug overdose deathsSpiritual interventionsExperienced needsService membersAddictive substancesSurvival needsUse treatmentMoral codeMedical conditionsOverdose deathsSpiritual symptomsInjuryMedical careNarrative reviewReligious Institutions as a Link to Substance use Treatment: Characterizing the Potential Service Population through National Survey Data
Heikkila HD, Edens EL, Stefanovics EA, Rhee TG, Rosenheck RA. Religious Institutions as a Link to Substance use Treatment: Characterizing the Potential Service Population through National Survey Data. Substance Use & Addiction Journal 2022, 43: 699-707. PMID: 35099366, DOI: 10.1080/08897077.2021.2007510.Peer-Reviewed Original ResearchConceptsSubstance use disordersDrug use disordersSUD treatmentUse disordersLife scoresUse diagnosesPast-year substance use disorderRepresentative cross-sectional surveyDrug use diagnosesSuch service useQuarter of adultsSubstance use diagnosesNational Epidemiologic SurveyRelated Conditions-IIISubstance use treatmentCross-sectional surveyCharacteristics of adultsProportion of adultsUse of servicesCurrent alcoholMultinomial logistic regressionEpidemiologic SurveyService useAfrican American groupSocio-demographic disadvantage
2021
An Interdisciplinary Approach to Metastatic Pancreatic Cancer and Comorbid Opioid Use Disorder Treatment Within a VA Health Care System.
Ruskin A, Falker CG, Edens EL, Bauer MR. An Interdisciplinary Approach to Metastatic Pancreatic Cancer and Comorbid Opioid Use Disorder Treatment Within a VA Health Care System. Federal Practitioner 2021, 38: s66-s71. PMID: 34733097, PMCID: PMC8560123, DOI: 10.12788/fp.0160.Peer-Reviewed Original ResearchPancreatic cancerOpioid use disorder treatmentVA health care systemActive substance use disorderAdvanced pancreatic cancerMetastatic pancreatic cancerUse disorder treatmentSubstance use disordersHealth care systemUse disordersDisorder treatmentCancer treatmentCare systemMultidisciplinary approachCancerTreatmentPatients
2018
Co-occurring Substance and Mental Health Disorders
Jorandby-Quinones L, Edens E, Rosenheck R. Co-occurring Substance and Mental Health Disorders. 2018, 307-333. DOI: 10.1007/978-1-4939-7438-2_20.ChaptersDual diagnosisMental health care deliveryHigh treatment burdenMore medical conditionsMental health care systemMental health disordersSubstance use disordersCo-occurring substanceEvolution of treatmentHealthcare delivery approachHealth care deliveryHealth care systemTreatment burdenMedical conditionsUse disordersHealth disordersMedical carePatientsCare deliveryPsychosocial conditionsIndividual diseasesCare systemDiagnosisTreatmentDisease
2016
Management of patients with issues related to opioid safety, efficacy and/or misuse: a case series from an integrated, interdisciplinary clinic
Becker WC, Merlin JS, Manhapra A, Edens EL. Management of patients with issues related to opioid safety, efficacy and/or misuse: a case series from an integrated, interdisciplinary clinic. Addiction Science & Clinical Practice 2016, 11: 3. PMID: 26818474, PMCID: PMC4730605, DOI: 10.1186/s13722-016-0050-0.Peer-Reviewed Original ResearchConceptsChronic painOpioid safetyInterdisciplinary clinicClinical scenariosCo-occurring chronic painMultimodal pain careManagement of patientsOpioid use disorderTreatment of patientsLack of efficacySimilar clinical scenariosComplex clinical scenariosQuality of careHazardous alcohol useSubstance abuse treatmentOpioid treatmentBuprenorphine/Case seriesPain careMultimodal treatmentClinical equipoisePrimary careUse disordersPainPatients
2014
Pilot results of a new model of addiction treatment: managing addiction as a chronic disease.
Edens EL, Donahue CA, Riordan CE. Pilot results of a new model of addiction treatment: managing addiction as a chronic disease. Connecticut Medicine 2014, 78: 487-91. PMID: 25314889.Peer-Reviewed Original ResearchConceptsSubstance use disordersAddiction treatmentChronic diseasesDSM-5 substance use disordersMonths of treatmentConcept pilot studyOutpatient addiction treatmentRandom alcoholAddiction treatment systemPilot resultsSustained abstinenceUse disordersIllness modelPilot studyDrug testsResidential careCarePilot participantsDay programTreatmentCurrent standardDiseasePotential effectivenessParticipantsAddiction
2011
Association of Substance Use and VA Service‐Connected Disability Benefits with Risk of Homelessness among Veterans
Edens EL, Kasprow W, Tsai J, Rosenheck RA. Association of Substance Use and VA Service‐Connected Disability Benefits with Risk of Homelessness among Veterans. American Journal On Addictions 2011, 20: 412-419. PMID: 21838839, DOI: 10.1111/j.1521-0391.2011.00166.x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAfghan Campaign 2001-AgedAged, 80 and overCase-Control StudiesFemaleHumansIll-Housed PersonsIraq War, 2003-2011MaleMental DisordersMental Health ServicesMiddle AgedRisk FactorsSubstance-Related DisordersUnited StatesUnited States Department of Veterans AffairsVeteransVeterans Disability ClaimsConceptsService-connected disabilityPersonality disorderUse disordersPathological gamblingClinical prevention effortsSubstance useLow-risk groupLow-risk subgroupsVA administrative dataSevere mental illnessSubstance use disordersAlcohol use disorderIllicit drug useMental health service usersOEF/OIFHealth service usersModifiable riskPrimary preventionSubgroup analysisReduced riskMental health usersVA servicesDrug useMental illnessLogistic regressionRates and Correlates of Pathological Gambling Among VA Mental Health Service Users
Edens EL, Rosenheck RA. Rates and Correlates of Pathological Gambling Among VA Mental Health Service Users. Journal Of Gambling Studies 2011, 28: 1-11. PMID: 21331515, DOI: 10.1007/s10899-011-9239-z.Peer-Reviewed Original ResearchConceptsPG diagnosisMental health service usersHealth service usersUse disordersPathological gamblingMH service usersVA health systemVeterans Health AdministrationCase-control studyDrug use disordersVA administrative dataMental health patientsSevere mental illnessSignificant independent associationMental health careAlcohol use disorderHeavy alcohol useChi-square testPast year ratesPast-year homelessnessClinical factorsService usersIndependent associationHealth patientsPrevalence ratesTreatment With Acamprosate in Patients With Schizophrenia Spectrum Disorders and Comorbid Alcohol Dependence
Ralevski E, O’Brien E, Jane JS, Dwan R, Dean E, Edens E, Arnaout B, Keegan K, Drew S, Petrakis I. Treatment With Acamprosate in Patients With Schizophrenia Spectrum Disorders and Comorbid Alcohol Dependence. Journal Of Dual Diagnosis 2011, 7: 64-73. PMID: 26954912, DOI: 10.1080/15504263.2011.569440.Peer-Reviewed Original ResearchEfficacy of acamprosateAlcohol dependenceSchizophrenia spectrum disordersMedication treatmentComorbid schizophreniaSignificant group x time interactionGroup x time interactionComorbid alcohol dependenceAlcohol use disorderSymptoms of schizophreniaX time interactionAcamprosate groupComorbid conditionsTreatment trialsAbstinent patientsClinical trialsSpectrum disorderAcamprosateGeneral populationUse disordersPatientsSchizoaffective disorderPositive symptomsSchizophrenic symptomsConsecutive days