2016
Changes in Cognitive Processing Speed, Mood, and Fatigue in an Observational Study of Persons With Multiple Sclerosis Treated With Dalfampridine-ER
Triche E, Ruiz J, Olson K, Lo A. Changes in Cognitive Processing Speed, Mood, and Fatigue in an Observational Study of Persons With Multiple Sclerosis Treated With Dalfampridine-ER. Clinical Neuropharmacology 2016, 39: 73-80. PMID: 26818040, DOI: 10.1097/wnf.0000000000000130.Peer-Reviewed Original ResearchConceptsDalfampridine extended releaseMultiple sclerosisWalk respondersObservational pre-post studyPre-post studyPerformance ScaleDegenerative neurological conditionDalfampridine-ERMS careFatigue scoresObservational studyResponder statusWeek 14Neurological conditionsSignificant improvementCognitive processing speedSelf-reported cognitionMood scoresWeeksSclerosisSDMTRespondersMoodDrugsDepression
2015
Effects of dalfampridine on multi-dimensional aspects of gait and dexterity in multiple sclerosis among timed walk responders and non-responders
Lo A, Ruiz J, Koenig C, Anderson B, Olson K, Triche E. Effects of dalfampridine on multi-dimensional aspects of gait and dexterity in multiple sclerosis among timed walk responders and non-responders. Journal Of The Neurological Sciences 2015, 356: 77-82. PMID: 26139339, DOI: 10.1016/j.jns.2015.06.008.Peer-Reviewed Original ResearchConceptsNon-dominant sideMultiple sclerosisMultiple Sclerosis Walking Scale-12Six-Spot Step TestD-EREffects of dalfampridineMinute walk testHole Peg TestRoutine clinical careWalk respondersWalk testGait impairmentAmbulatory personsPeg TestGross dexterityClinical carePotential treatmentScale-12Block TestSclerosisGaitStep testRespondersFurther investigationSignificant improvement