2016
Changes in Cognitive Processing Speed, Mood, and Fatigue in an Observational Study of Persons With Multiple Sclerosis Treated With Dalfampridine-ER
Triche E, Ruiz J, Olson K, Lo A. Changes in Cognitive Processing Speed, Mood, and Fatigue in an Observational Study of Persons With Multiple Sclerosis Treated With Dalfampridine-ER. Clinical Neuropharmacology 2016, 39: 73-80. PMID: 26818040, DOI: 10.1097/wnf.0000000000000130.Peer-Reviewed Original ResearchConceptsDalfampridine extended releaseMultiple sclerosisWalk respondersObservational pre-post studyPre-post studyPerformance ScaleDegenerative neurological conditionDalfampridine-ERMS careFatigue scoresObservational studyResponder statusWeek 14Neurological conditionsSignificant improvementCognitive processing speedSelf-reported cognitionMood scoresWeeksSclerosisSDMTRespondersMoodDrugsDepression
2015
Effects of dalfampridine on multi-dimensional aspects of gait and dexterity in multiple sclerosis among timed walk responders and non-responders
Lo A, Ruiz J, Koenig C, Anderson B, Olson K, Triche E. Effects of dalfampridine on multi-dimensional aspects of gait and dexterity in multiple sclerosis among timed walk responders and non-responders. Journal Of The Neurological Sciences 2015, 356: 77-82. PMID: 26139339, DOI: 10.1016/j.jns.2015.06.008.Peer-Reviewed Original ResearchConceptsNon-dominant sideMultiple sclerosisMultiple Sclerosis Walking Scale-12Six-Spot Step TestD-EREffects of dalfampridineMinute walk testHole Peg TestRoutine clinical careWalk respondersWalk testGait impairmentAmbulatory personsPeg TestGross dexterityClinical carePotential treatmentScale-12Block TestSclerosisGaitStep testRespondersFurther investigationSignificant improvementA Pilot Study: examining the effects and tolerability of structured dance intervention for individuals with multiple sclerosis
Mandelbaum R, Triche E, Fasoli S, Lo A. A Pilot Study: examining the effects and tolerability of structured dance intervention for individuals with multiple sclerosis. Disability And Rehabilitation 2015, 38: 218-222. PMID: 25875049, DOI: 10.3109/09638288.2015.1035457.Peer-Reviewed Original ResearchConceptsDynamic Gait IndexPhysical activity adherenceMultiple sclerosisPhysical activityDance interventionActivities-specific Balance Confidence ScaleGodin Leisure Time QuestionnaireIssues of tolerabilityBalance Confidence ScaleEnjoyable physical activityActivity adherenceMS symptomsGait IndexNeurological impairmentMS populationElderly populationFeasible interventionPilot studyConfidence ScaleTolerabilityInterventionNeurodegenerative populationsSclerosisTime QuestionnaireBehavioral changes
2013
Combination of Robot-Assisted and Conventional Body-Weight–Supported Treadmill Training Improves Gait in Persons With Multiple Sclerosis
Ruiz J, Labas M, Triche E, Lo A. Combination of Robot-Assisted and Conventional Body-Weight–Supported Treadmill Training Improves Gait in Persons With Multiple Sclerosis. Journal Of Neurologic Physical Therapy 2013, 37: 187-193. PMID: 24189336, DOI: 10.1097/npt.0000000000000018.Peer-Reviewed Original ResearchConceptsFunctional Reach TestGait trainingDT groupTreadmill trainingWalk testTherapy groupIT groupRobot-assisted treadmill trainingImmediate therapy groupConcurrent comparison groupMajority of personsQuality of lifePre-post improvementsMultiple sclerosisEffective therapyReach testOutcome measuresBody weightFRT distancePhase ISame sessionVideo AbstractComparison groupPhase IIRobot-AssistedExploring the Role of Antithrombin Replacement for the Treatment of Preeclampsia: A Prospective Randomized Evaluation of the Safety and Efficacy of Recombinant Antithrombin in Very Preterm Preeclampsia (PRESERVE‐1)
Paidas MJ, Sibai BM, Triche EW, Frieling J, Lowry S, Group T. Exploring the Role of Antithrombin Replacement for the Treatment of Preeclampsia: A Prospective Randomized Evaluation of the Safety and Efficacy of Recombinant Antithrombin in Very Preterm Preeclampsia (PRESERVE‐1). American Journal Of Reproductive Immunology 2013, 69: 539-544. PMID: 23444920, DOI: 10.1111/aji.12091.Peer-Reviewed Original ResearchConceptsProspective Randomized EvaluationAntithrombin replacementWeeks' gestationRandomized EvaluationRecombinant antithrombinTreatment of preeclampsiaRecombinant human ATExpectant managementPreterm preeclampsiaPrimary endpointMaternal indicationsGestational ageStudy enrollmentAT therapyPreeclampsia studyPreeclampsiaGestationHuman ATAT replacementPharmacokinetic activityAntithrombinEfficacySafetyLaboratory assaysDelivery
2008
Improving Gait in Multiple Sclerosis Using Robot-Assisted, Body Weight Supported Treadmill Training
Lo A, Triche E. Improving Gait in Multiple Sclerosis Using Robot-Assisted, Body Weight Supported Treadmill Training. Neurorehabilitation And Neural Repair 2008, 22: 661-671. PMID: 18971381, DOI: 10.1177/1545968308318473.Peer-Reviewed Original ResearchConceptsExpanded Disability Status ScaleMultiple sclerosisGait outcomesGait impairmentTreadmill trainingGait trainingTreatment groupsBody weightBaseline Expanded Disability Status ScaleKurtzke Expanded Disability Status ScalePrimary progressive multiple sclerosisDouble limb support timeProgressive gait impairmentProgressive multiple sclerosisDisability Status ScaleMajority of patientsSmall pilot studyGait functionStatus ScaleTreatment gapAffected limbOutpatient interventionStudy populationSupport timeCrossover design
2007
Use of recombinant activated factor VII for massive postpartum hemorrhage
HOSSAIN N, SHAMSI T, HAIDER S, SOOMRO N, KHAN NH, MEMON GU, FARZANA T, ANSARI S, TRICHE EW, KUCZYNSKI E, LOCKWOOD CJ, PAIDAS MJ. Use of recombinant activated factor VII for massive postpartum hemorrhage. Acta Obstetricia Et Gynecologica Scandinavica 2007, 86: 1200-1206. PMID: 17851797, DOI: 10.1080/00016340701619324.Peer-Reviewed Original ResearchConceptsMassive postpartum hemorrhageDepartment of ObstetricsPostpartum hemorrhageRecombinant factor VIIFactor VIIMaternal mortalityActivated recombinant factor VIIPacked red cell transfusionSurgical intensive care unitCost of rFVIIaCorrection of coagulopathyCivil Hospital KarachiRed cell transfusionPreservation of fertilityIntensive care unitLower prothrombin timeRate of hysterectomyAdministration of drugsLower maternal mortalityCell transfusionHospital KarachiAdverse eventsBlood lossCare unitDow University