2024
Drawbacks to Strengthening Neural Salience Encoding: A Link Between Cortisol and Risky Drinking
Harris B, Sinha R, Goldfarb E. Drawbacks to Strengthening Neural Salience Encoding: A Link Between Cortisol and Risky Drinking. Journal Of Neuroscience 2024, 44: e1027242024. PMID: 39147591, PMCID: PMC11450530, DOI: 10.1523/jneurosci.1027-24.2024.Peer-Reviewed Original ResearchAlcohol motivationInfluence later behaviorEnhance memorySalience responseFemale social drinkersAlcohol drinkingEmotionally salient experiencesResponse to alcoholDouble-blind cross-over designMemory biasSalient memoriesAlcohol-related eventsRisky alcohol drinkingSocial drinkersMotivated behaviorMaladaptive consequencesLateral behaviorCross-over designRisky drinkingMemoryRodent modelsHuman researchSalienceRisky drinkersCortisolAcute Stress Effects on Statistical Learning and Episodic Memory
Sherman B, Huang I, Wijaya E, Turk-Browne N, Goldfarb E. Acute Stress Effects on Statistical Learning and Episodic Memory. Journal Of Cognitive Neuroscience 2024, 36: 1741-1759. PMID: 38713878, PMCID: PMC11223726, DOI: 10.1162/jocn_a_02178.Peer-Reviewed Original ResearchEpisodic memoryAcute stressStatistical learningEffects of acute stressStress-induced cortisol levelsImpaired episodic memoryModulate learning processesAcute stress effectsImpact hippocampal functionEpisodic encodingRodent workEvidence of learningHippocampal functionStress effectsHippocampal pathwaysLearning tasksBehavioral experimentsPreliminary evidenceCortisol levelsNo stressMemoryMultiple measuresHippocampusScene categoriesParticipantsIntegrating and fragmenting memories under stress and alcohol
Loetscher K, Goldfarb E. Integrating and fragmenting memories under stress and alcohol. Neurobiology Of Stress 2024, 30: 100615. PMID: 38375503, PMCID: PMC10874731, DOI: 10.1016/j.ynstr.2024.100615.Peer-Reviewed Original ResearchMemory representationsMemory integrationMemory-guided behaviorPre-existing schemaEffects of alcoholMemory bindingAversive learningNegative affectCognitive mechanismsPreclinical findingsMemoryDesign appropriate interventionsIndividual experienceAppropriate interventionsFragmented memoryAlcoholCausal structureAffectBehaviorMultiple levelsFindingsRepresentationStressSchemaIntervention
2023
Acute Stress Enhances Memory and Preference for Smoking-Related Associations in Smokers
Lee J, Kang S, Maier S, Lee S, Goldfarb E, Ahn W. Acute Stress Enhances Memory and Preference for Smoking-Related Associations in Smokers. Nicotine & Tobacco Research 2023, 26: 333-341. PMID: 37589502, DOI: 10.1093/ntr/ntad152.Peer-Reviewed Original ResearchSmoking-related itemsMemory biasesAcute stressNicotine dependenceAccuracy of memoryStress-induced relapseLaboratory-based stressorRole of stressMemory biasMemory recognitionContext memoryLaboratory paradigmContextual memoryVisual stimuliNicotine seekingAssociative memorySevere nicotine dependenceRewarding memoryMemoryControl conditionRelated contextGreater preferenceCurrent studyPotential interventionsItemsMultiple Memory Subsystems: Reconsidering Memory in the Mind and Brain
Sherman B, Turk-Browne N, Goldfarb E. Multiple Memory Subsystems: Reconsidering Memory in the Mind and Brain. Perspectives On Psychological Science 2023, 19: 103-125. PMID: 37390333, PMCID: PMC10756937, DOI: 10.1177/17456916231179146.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMemory representationsDistinct brain systemsLong-term memoryBrain structuresCross-species findingsSame brain structuresMemory-related structuresMemory researchBrain systemsMemory typesMemory organizationMemoryFuture researchOrganizational principlesClassic theoryMemory subsystemNovel perspectiveRepresentationAmygdalaResearchRecent workLearningMindTheoryDistinct types
2021
Elemental and configural threat learning bias extinction generalization
Goldfarb EV, Blow T, Dunsmoor JE, Phelps EA. Elemental and configural threat learning bias extinction generalization. Neurobiology Of Learning And Memory 2021, 180: 107405. PMID: 33609739, PMCID: PMC8076085, DOI: 10.1016/j.nlm.2021.107405.Peer-Reviewed Original ResearchConceptsExtinction generalizationCompound cueNegative emotional eventsTime of learningGroups of participantsMultitude of detailsThreat conditioningElemental learningAversive outcomesEmotional eventsExtinction strategiesExtinction taskAversive eventsEmotional experienceThreat responsesEmotional responsesAbsence of shockCuesMemorySingle representationParticipantsLearningToneImportant implicationsExtinction
2019
Acute Stress Throughout the Memory Cycle: Diverging Effects on Associative and Item Memory
Goldfarb EV, Tompary A, Davachi L, Phelps EA. Acute Stress Throughout the Memory Cycle: Diverging Effects on Associative and Item Memory. Journal Of Experimental Psychology General 2019, 148: 13-29. PMID: 30221962, PMCID: PMC6312485, DOI: 10.1037/xge0000472.Peer-Reviewed Original ResearchConceptsItem memoryAssociative memoryAssociative recognition taskAcute stressForms of memoryStress-induced cortisolAcute stress effectsNeutral objectsNegative wordsRecognition taskSubjective arousalSubjects designMemoryItemsDifferent patternsArousalAssociativeWordsTaskParticipantsStress effectsRelationshipCortisolQuadratic relationshipKey differences
2018
Enhancing memory with stress: Progress, challenges, and opportunities
Goldfarb EV. Enhancing memory with stress: Progress, challenges, and opportunities. Brain And Cognition 2018, 133: 94-105. PMID: 30553573, PMCID: PMC9972486, DOI: 10.1016/j.bandc.2018.11.009.Peer-Reviewed Original ResearchConceptsLong-term memoryDeclarative memoryHippocampal-dependent memory processesMemory-related brain regionsHippocampus-dependent memoryMemory processesMemory functionRodent researchMemoryBrain regionsCentral stress responseFuture researchAcute stressPeripheral stress responsesStress effectsModulatory factorsRodent studiesPositive effectStress responseHuman studiesTranslational gapHumansResearchPhysiological mechanismsRodents
2017
Acute Stress Time-dependently Modulates Multiple Memory Systems
Goldfarb EV, Mendelevich Y, Phelps EA. Acute Stress Time-dependently Modulates Multiple Memory Systems. Journal Of Cognitive Neuroscience 2017, 29: 1877-1894. PMID: 28699809, DOI: 10.1162/jocn_a_01167.Peer-Reviewed Original ResearchLow lifetime stress exposure is associated with reduced stimulus–response memory
Goldfarb EV, Shields GS, Daw ND, Slavich GM, Phelps EA. Low lifetime stress exposure is associated with reduced stimulus–response memory. Learning & Memory 2017, 24: 162-168. PMID: 28298555, PMCID: PMC5362698, DOI: 10.1101/lm.045179.117.Peer-Reviewed Original ResearchConceptsLifetime stress exposureStimulus-response memoryStress exposureLifetime stressCumulative lifetime stress exposureStimulus-response associationsForms of psychopathologyYoung adultsHigh lifetime stressLow stress exposureCumulative stress exposureContext memoryMemory performanceDiminished resilienceSR associationsNegative outcomesMemoryModerate levelsNegative effectsLow levelsComputational modelingLow stressAdultsAssessment systemCognition
2016
Memory-Guided Attention: Independent Contributions of the Hippocampus and Striatum
Goldfarb EV, Chun MM, Phelps EA. Memory-Guided Attention: Independent Contributions of the Hippocampus and Striatum. Neuron 2016, 89: 317-324. PMID: 26777274, PMCID: PMC4871761, DOI: 10.1016/j.neuron.2015.12.014.Peer-Reviewed Original ResearchConceptsContext memoryMemory-guided attentionFunctional magnetic resonance imagingStimulus-response associationsVisual search taskMedial temporal lobeFacilitate attentionAttention benefitsIndividual differencesSearch taskMemory systemTemporal lobeMemoryIndependent contributionNovel evidenceFuture encountersReinforcement learningAttentionMagnetic resonance imagingStriatumHippocampusResonance imagingTaskLearningFacilitation