2017
Atomoxetine in abstinent cocaine users: Cognitive, subjective and cardiovascular effects
DeVito EE, Herman AI, Konkus NS, Zhang H, Sofuoglu M. Atomoxetine in abstinent cocaine users: Cognitive, subjective and cardiovascular effects. Pharmacology Biochemistry And Behavior 2017, 159: 55-61. PMID: 28716656, PMCID: PMC5573182, DOI: 10.1016/j.pbb.2017.07.002.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic Uptake InhibitorsAdultAffectAtomoxetine HydrochlorideAttentionCocaine-Related DisordersCognitionCross-Over StudiesDose-Response Relationship, DrugDouble-Blind MethodFemaleHemodynamicsHumansInhibition, PsychologicalMaleMemory, Short-TermMiddle AgedNeuropsychological TestsSex CharacteristicsConceptsCocaine use disorderMeasures of attentionAbstinent cocaine usersSubjective drug effectsHuman laboratory studiesResponse inhibitionCognitive enhancementAbstinent individualsCognitive enhancersBehavioral treatmentAddictive processClinical populationsAtomoxetineCognitive impairmentNorepinephrine transporter inhibitorUse disordersCocaine usersCardiovascular effectsMoodMedication effectsPoor clinical outcomeDose-dependent effectIndividualsDrug effectsMemory
2012
Impaired inhibitory control in ‘internet addiction disorder’: A functional magnetic resonance imaging study
Dong G, DeVito EE, Du X, Cui Z. Impaired inhibitory control in ‘internet addiction disorder’: A functional magnetic resonance imaging study. Psychiatry Research 2012, 203: 153-158. PMID: 22892351, PMCID: PMC3650485, DOI: 10.1016/j.pscychresns.2012.02.001.Peer-Reviewed Original ResearchConceptsIAD groupMagnetic resonance imaging studyPrevalent mental health concernAddiction disordersResonance imaging studyFunctional magnetic resonance imaging studyPosterior cingulate cortexMental health concernsImpaired inhibitory controlHealthy controlsHealthy peersInternet addiction disorderCingulate cortexImaging studiesHealth concernDisordersNeurobiological underpinningsInhibitory controlResponse inhibitionNeural correlatesResponse inhibition processesPotential heterogeneityPresent studyGroupMemantine, an NMDA receptor antagonist, differentially influences Go/No-Go performance and fMRI activity in individuals with and without a family history of alcoholism
Jamadar S, DeVito EE, Jiantonio RE, Meda SA, Stevens MC, Potenza MN, Krystal JH, Pearlson GD. Memantine, an NMDA receptor antagonist, differentially influences Go/No-Go performance and fMRI activity in individuals with and without a family history of alcoholism. Psychopharmacology 2012, 222: 129-140. PMID: 22311382, PMCID: PMC3674025, DOI: 10.1007/s00213-011-2628-2.Peer-Reviewed Original ResearchConceptsNMDA receptor antagonistFamily historyFHN subjectsReceptor antagonistFHP subjectsN-methyl-D-aspartate receptor functionReceptor functionIdentical-appearing placeboEffects of memantineFMRI activityNMDA receptor functionCorrect rejectsSingle doseMemantineGo/No-Go taskSeparate daysTemporal regionsCingulate activation
2008
Methylphenidate improves response inhibition but not reflection–impulsivity in children with attention deficit hyperactivity disorder (ADHD)
DeVito EE, Blackwell AD, Clark L, Kent L, Dezsery AM, Turner DC, Aitken MR, Sahakian BJ. Methylphenidate improves response inhibition but not reflection–impulsivity in children with attention deficit hyperactivity disorder (ADHD). Psychopharmacology 2008, 202: 531. PMID: 18818905, PMCID: PMC2704617, DOI: 10.1007/s00213-008-1337-y.Peer-Reviewed Original ResearchConceptsAttention deficit hyperactivity disorderInformation Sampling TaskResponse inhibitionDeficit hyperactivity disorderHyperactivity disorderEducation-matched control groupPerformance of childrenForms of impulsivityStop-signal taskMeasures of impulsivityEffects of methylphenidateMulti-factorial constructADHD groupSignal taskImpulsivityPoor decisionsBehavioral symptomsMethylphenidateSampling tasksSame measuresPlacebo-controlled trialTaskChildrenImpairmentMeasures