2018
Can neuroimaging help combat the opioid epidemic? A systematic review of clinical and pharmacological challenge fMRI studies with recommendations for future research
Moningka H, Lichenstein S, Worhunsky PD, DeVito EE, Scheinost D, Yip SW. Can neuroimaging help combat the opioid epidemic? A systematic review of clinical and pharmacological challenge fMRI studies with recommendations for future research. Neuropsychopharmacology 2018, 44: 259-273. PMID: 30283002, PMCID: PMC6300537, DOI: 10.1038/s41386-018-0232-4.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsBrainHumansMagnetic Resonance ImagingNeuroimagingOpioid-Related DisordersResearch DesignConceptsOpioid use disorderOpioid epidemicTreatment responseTask-based fMRI paradigmsUrgent public health problemMedication-assisted treatmentPrescription opioid usersCurrent opioid epidemicPublic health problemEvidence-based treatmentsPaucity of literatureHeroin cuesOpioid medicationsRelapse rateOpioid systemOpioid usersFuture neuroimaging studiesSignificant individual variabilityHealthcare costsWithdrawal effectsHealthy individualsHealth problemsSystematic reviewExtended abstinenceNeuroimaging studies
2014
Hippocampal volume mediates the relationship between measures of pre-treatment cocaine use and within-treatment cocaine abstinence
Xu J, Kober H, Wang X, DeVito EE, Carroll KM, Potenza MN. Hippocampal volume mediates the relationship between measures of pre-treatment cocaine use and within-treatment cocaine abstinence. Drug And Alcohol Dependence 2014, 143: 74-80. PMID: 25115748, PMCID: PMC4165405, DOI: 10.1016/j.drugalcdep.2014.07.007.Peer-Reviewed Original ResearchConceptsCocaine-dependent patientsHippocampal volumeTreatment outcomesCocaine useCocaine use severityCocaine-negative urine samplesGreater hippocampal volumePoor treatment outcomesPatient groupTreatment trialsContinuous abstinenceHigh-resolution magnetic resonance brain imagesTreatment responseIndividualized treatmentHealthy comparison individualsPatientsCocaine abstinenceCocaine dependenceBehavioral therapyCocaine-related cuesMore daysUrine samplesContingency managementSignificant differencesSignificant correlation