2020
Impulsivity across Substance Use Categories: Consideration of Sex/Gender
DeVito EE, Weinberger AH, Pang RD, Petersen N, Fagle T, Allen AM. Impulsivity across Substance Use Categories: Consideration of Sex/Gender. Current Behavioral Neuroscience Reports 2020, 7: 109-127. PMID: 33614396, PMCID: PMC7891462, DOI: 10.1007/s40473-020-00213-6.Peer-Reviewed Original ResearchSubstance use disordersUse disordersSubstance use groupSubstance use categoriesSubstance-using populationsHigh impulsivitySubstance use severityClinical severityUse of substancesTreatment outcomesInclusion criteriaSex/genderSubstance use behaviorsSex/gender differencesReviewThe goalUse severityRecent evidenceSeverityRange of substancesRole of impulsivityDisordersImpulsivityFemale individualsGender differencesCurrent body
2016
Gender-related Differences in Food Craving and Obesity.
Hallam J, Boswell RG, DeVito EE, Kober H. Gender-related Differences in Food Craving and Obesity. The Yale Journal Of Biology And Medicine 2016, 89: 161-73. PMID: 27354843, PMCID: PMC4918881.Peer-Reviewed Original ResearchConceptsGender-related differencesFood cravingsWeight loss treatmentWeight-related outcomesMore effective treatmentsGender differencesMenstrual cycleEffective treatmentLoss treatmentObesity epidemicObesityTreatment approachesClear gender differencesHealth consequencesWeight lossGender-based differencesCravingTreatmentAddiction literatureDifferencesPrevalence
2014
Gender differences in clinical outcomes for cocaine dependence: Randomized clinical trials of behavioral therapy and disulfiram
DeVito EE, Babuscio TA, Nich C, Ball SA, Carroll KM. Gender differences in clinical outcomes for cocaine dependence: Randomized clinical trials of behavioral therapy and disulfiram. Drug And Alcohol Dependence 2014, 145: 156-167. PMID: 25457739, PMCID: PMC4268325, DOI: 10.1016/j.drugalcdep.2014.10.007.Peer-Reviewed Original ResearchConceptsRandomized clinical trialsClinical trialsClinical outcomesTreatment outcomesCocaine dependenceBehavioral therapyBehavioral treatment conditionsPoor treatment outcomesEvidence-based treatmentsGender differencesWidespread clinical implementationPoor outcomePharmacological treatmentMedication conditionAddiction pharmacotherapyCocaine useSecondary analysisBehavioral treatmentClinical implementationWomenCareful assessmentDisulfiramOutcomesTrialsMen
2013
Gender differences in a clinical trial for prescription opioid dependence
McHugh RK, DeVito EE, Dodd D, Carroll KM, Potter JS, Greenfield SF, Connery HS, Weiss RD. Gender differences in a clinical trial for prescription opioid dependence. Journal Of Substance Use And Addiction Treatment 2013, 45: 38-43. PMID: 23313145, PMCID: PMC3626739, DOI: 10.1016/j.jsat.2012.12.007.Peer-Reviewed Original ResearchConceptsPrescription opioid dependenceOpioid dependenceClinical trialsOpioid dependence severityPrescription drug dependenceLarge clinical trialsOpioid use outcomesGreater functional impairmentRoute of administrationSubstance use disordersGender differencesGreater psychiatric severityClinical characteristicsMedication doseStudy treatmentOpioid outcomesFunctional impairmentTreatment outcomesPre-treatment differencesPsychiatric severityTreatment retentionUse disordersLegitimate prescriptionDrug dependenceOpioids
2011
Reliance on habits at the expense of goal-directed control following dopamine precursor depletion
de Wit S, Standing HR, DeVito EE, Robinson OJ, Ridderinkhof KR, Robbins TW, Sahakian BJ. Reliance on habits at the expense of goal-directed control following dopamine precursor depletion. Psychopharmacology 2011, 219: 621-631. PMID: 22134475, PMCID: PMC3249188, DOI: 10.1007/s00213-011-2563-2.Peer-Reviewed Original ResearchConceptsDopamine functionOutcome devaluation testRecent animal studiesGoal-directed action controlRole of dopamineStimulus-response habitsPlacebo groupDietary interventionHabitual controlTyrosine depletionHealthy volunteersDietary phenylalanineAnimal studiesFemale volunteersStimulus-response learningAction controlGoal-directed actionsDopamineSubject comparisonsVolunteersOutcomesGender differencesRewarding outcomesInitial learning phaseGoal-directed control
2010
Dopamine precursor depletion improves punishment prediction during reversal learning in healthy females but not males
Robinson OJ, Standing HR, DeVito EE, Cools R, Sahakian BJ. Dopamine precursor depletion improves punishment prediction during reversal learning in healthy females but not males. Psychopharmacology 2010, 211: 187-195. PMID: 20495788, PMCID: PMC2892070, DOI: 10.1007/s00213-010-1880-1.Peer-Reviewed Original ResearchConceptsDA synthesisHealthy individualsParkinson's diseaseMale subjectsPlacebo-controlled crossover designCertain psychiatric disordersPunishment processingDA depletionDopamine synthesisHealthy femalesPsychiatric disordersCrossover designFemale subjectsDiseaseNeurotransmitter dopamineGender biasesReward processingThree-way interactionReversal learningSubjectsDepletion procedurePunishment predictionGender differencesSignificant improvement