2024
Healthy lifestyle change and all-cause and cancer mortality in the European Prospective Investigation into Cancer and Nutrition cohort
Matta K, Viallon V, Botteri E, Peveri G, Dahm C, Nannsen A, Olsen A, Tjønneland A, Elbaz A, Artaud F, Marques C, Kaaks R, Katzke V, Schulze M, Llanaj E, Masala G, Pala V, Panico S, Tumino R, Ricceri F, Derksen J, Nøst T, Sandanger T, Borch K, Quirós J, Castro-Espin C, Sánchez M, Atxega A, Cirera L, Guevara M, Manjer J, Tin Tin S, Heath A, Touvier M, Goldberg M, Weiderpass E, Gunter M, Freisling H, Riboli E, Ferrari P. Healthy lifestyle change and all-cause and cancer mortality in the European Prospective Investigation into Cancer and Nutrition cohort. BMC Medicine 2024, 22: 210. PMID: 38807179, PMCID: PMC11134634, DOI: 10.1186/s12916-024-03362-7.Peer-Reviewed Original ResearchConceptsHealthy lifestyle indexAssociated with all-causeHealthy lifestyle changesEuropean Prospective InvestigationRisk of deathCancer mortalityFollow-up questionnaireAll-causeLifestyle changesProspective InvestigationRate advancement periodsUnhealthy lifestyle changesRisk of noncommunicable diseasesCancer and NutritionCancer-free adultsBody mass indexBackgroundHealthy lifestylesLifestyle behaviorsNutrition CohortLifestyle indexLifestyle ProfilePhysical activityAssociated with mortalityNoncommunicable diseasesChange scoresOccupation and tongue cancer in Nordic countries
Peltonen J, Nikkilä R, Al-Samadi A, Mäkitie A, Martinsen J, Kjaerheim K, Lynge E, Sparen P, Tryggvadottir L, Weiderpass E, Salo T, Pukkala E. Occupation and tongue cancer in Nordic countries. BMC Oral Health 2024, 24: 506. PMID: 38685000, PMCID: PMC11059716, DOI: 10.1186/s12903-024-04172-2.Peer-Reviewed Original ResearchConceptsStandardized incidence ratioNordic Occupational CancerNational incidence ratesTongue cancerBeverage workersConsumption of alcoholEffects of carcinogen exposureSignificant SIRsIncidence ratiosResultsAmong menInactive personsOccupational cancerIncidence rateNordic countriesOccupational categoriesMethodsThe dataArtistic workersRisk variationMale farmersConclusionsThese findingsCarcinogen exposureWorkersForestry workersCancerTobaccoDietary intake of plant- and animal-derived protein and incident cardiovascular diseases: the pan-European EPIC-CVD case–cohort study
Zheng J, Steur M, Imamura F, Freisling H, Johnson L, van der Schouw Y, Tong T, Weiderpass E, Bajracharya R, Crous-Bou M, Dahm C, Heath A, Ibsen D, Jannasch F, Katzke V, Masala G, Moreno-Iribas C, Sacerdote C, Schulze M, Sieri S, Wareham N, Danesh J, Butterworth A, Forouhi N. Dietary intake of plant- and animal-derived protein and incident cardiovascular diseases: the pan-European EPIC-CVD case–cohort study. American Journal Of Clinical Nutrition 2024, 119: 1164-1174. PMID: 38479550, PMCID: PMC11130694, DOI: 10.1016/j.ajcnut.2024.03.006.Peer-Reviewed Original ResearchConceptsIschemic heart diseaseDietary protein intakeProtein intakeCase-cohort studyCardiovascular diseaseIncident cardiovascular diseaseFatal strokeAssociated with lower incidenceIncidence of fatal strokeRisk of cardiovascular diseaseEuropean Prospective InvestigationPrentice-weighted Cox regressionAssociated with incident cardiovascular diseaseOverall CVDIncident CVD casesIntake of plantMacronutrient intakeStroke incidenceProtein consumptionSubcohort membersIsocaloric substitutionDietary patternsDietary intakeNever smokersProspective InvestigationManaging menopause after cancer
Hickey M, Basu P, Sassarini J, Stegmann M, Weiderpass E, Nakawala Chilowa K, Yip C, Partridge A, Brennan D. Managing menopause after cancer. The Lancet 2024, 403: 984-996. PMID: 38458217, DOI: 10.1016/s0140-6736(23)02802-7.Peer-Reviewed Original ResearchConceptsPremature ovarian insufficiencyMenopausal symptomsRisk of chronic conditionsLong-term effects of cancer treatmentHormone therapyOvarian insufficiencyPatient-focused modelModels of careVasomotor symptomsBreast cancerEffects of cancer treatmentCancer treatmentSexual dysfunctionHigh-income countriesMenopausal hormone therapyQuality of lifeTreatment-induced symptomsLow-income countriesNon-hormonal treatmentsNon-hormonal optionsChronic conditionsManaging menopausal symptomsManaging menopauseDiagnose menopauseVaginal estrogenBMI and breast cancer risk around age at menopause
Von Holle A, Adami H, Baglietto L, Berrington de Gonzalez A, Bertrand K, Blot W, Chen Y, DeHart J, Dossus L, Eliassen A, Fournier A, Garcia-Closas M, Giles G, Guevara M, Hankinson S, Heath A, Jones M, Joshu C, Kaaks R, Kirsh V, Kitahara C, Koh W, Linet M, Park H, Masala G, Mellemkjaer L, Milne R, O'Brien K, Palmer J, Riboli E, Rohan T, Shrubsole M, Sund M, Tamimi R, Tin Tin S, Visvanathan K, Vermeulen R, Weiderpass E, Willett W, Yuan J, Zeleniuch-Jacquotte A, Nichols H, Sandler D, Swerdlow A, Schoemaker M, Weinberg C. BMI and breast cancer risk around age at menopause. Cancer Epidemiology 2024, 89: 102545. PMID: 38377945, PMCID: PMC10942753, DOI: 10.1016/j.canep.2024.102545.Peer-Reviewed Original ResearchConceptsBreast cancer riskCancer riskHazard ratioBreast cancer hazard ratioCancer hazard ratioFive-unit incrementNatural menopauseBreast cancer etiologyHigher body mass indexLoss to follow-upAssociated with decreased riskBreast cancer diagnosisMenopausal status groupsBody mass indexYears age rangeMenopausal hormone therapyPrimary time scalePerson-timeCancer etiologyLoss of ovarian functionCancer diagnosisMass indexBMIPositive associationStatus groupsCirculating endogenous sex steroids and risk of differentiated thyroid carcinoma in men and women
Rinaldi S, Dossus L, Keski‐Rahkonen P, Kiss A, Navionis A, Biessy C, Travis R, Weiderpass E, Romieu I, Eriksen A, Tjonneland A, Kvaskoff M, Canonico M, Truong T, Katzke V, Kaaks R, Catalano A, Panico S, Masala G, Tumino R, Lukic M, Olsen K, Zamora‐Ros R, Santiuste C, Atxega A, Guevara M, Rodriguez‐Barranco M, Sandstrom M, Hennings J, Almquist M, Kouassivi E, Christakoudi S, Gunter M, Franceschi S. Circulating endogenous sex steroids and risk of differentiated thyroid carcinoma in men and women. International Journal Of Cancer 2024, 154: 2064-2074. PMID: 38357914, DOI: 10.1002/ijc.34872.Peer-Reviewed Original ResearchConceptsSex hormone binding globulinSex steroid hormonesThyroid cancerRisk of differentiated thyroid carcinomaOdds ratioSex steroidsSex hormone binding globulin concentrationsSteroid hormonesCancer-free controlsPre-menopausal womenRisk of differentiated TCEuropean Prospective InvestigationPost-menopausal womenEndogenous sex steroidsBorderline significant increaseConditional logistic regression modelsSex steroid productionNo significant associationCirculating sex steroidsCirculating sex steroid hormonesPostmenopausal womenConcentrations of testosteroneProgesterone/estradiol ratioThyroid carcinomaBorderline decreaseFemale reproductive histories and the risk of chronic obstructive pulmonary disease
Liang C, Chung H, Dobson A, Sandin S, Weiderpass E, Mishra G. Female reproductive histories and the risk of chronic obstructive pulmonary disease. Thorax 2024, 79: 508-514. PMID: 38350732, DOI: 10.1136/thorax-2023-220388.Peer-Reviewed Original ResearchConceptsRisk of chronic obstructive pulmonary diseaseChronic obstructive pulmonary diseaseFemale reproductive factorsReproductive factorsObstructive pulmonary diseaseNatural menopauseBirth yearIncreased risk of COPDPulmonary diseaseBody mass indexDevelopment of chronic obstructive pulmonary diseaseEducation levelCox regression modelsMass indexReproductive historyIncreased riskCohort differencesStillbirthRegression modelsFemale reproductive historyMenarcheMedian follow-upWomenFemale hormonal environmentCohortWorld Oncology Forum amplifies its appeal in global fight against cancer
Cavalli F, Mikkelsen B, Weiderpass E, Sullivan R, Jaffray D, Gospodarowicz M. World Oncology Forum amplifies its appeal in global fight against cancer. The Lancet Oncology 2024, 25: 170-174. PMID: 38301688, DOI: 10.1016/s1470-2045(24)00010-x.Peer-Reviewed Original ResearchStrategies to decrease inequalities in cancer therapeutics, care and prevention
Ringborg U, von Braun J, Celis J, Baumann M, Berns A, Eggermont A, Heard E, Heitor M, Chandy M, Chen C, Costa A, De Lorenzo F, De Robertis E, Dubee F, Ernberg I, Gabriel M, Helland Å, Henrique R, Jönsson B, Kallioniemi O, Korbel J, Krause M, Lowy D, Michielin O, Nagy P, Oberst S, Paglia V, Parker M, Ryan K, Sawyers C, Schüz J, Silkaitis K, Solary E, Thomas D, Turkson P, Weiderpass E, Yang H. Strategies to decrease inequalities in cancer therapeutics, care and prevention. Molecular Oncology 2024, 18: 245-279. PMID: 38135904, PMCID: PMC10850793, DOI: 10.1002/1878-0261.13575.Peer-Reviewed Original ResearchConceptsComprehensive cancer centreEuropean Academy of Cancer SciencesEurope's Beating Cancer PlanHealthcare systemCancer research continuumPrevention modalitiesCost-effective healthcareCancer research infrastructureCancer PlanCancer incidencePatient needsPatient careResearch continuumPrevention opportunitiesPrevention programsCancer preventionCancer centreOutcomes researchHealthcareEconomic statusPontifical Academy of SciencesDecreasing inequalityState-of-the-art patient careCancer scienceResearch portfolio
2023
Association of hormonal and reproductive factors with differentiated thyroid cancer risk in women: a pooled prospective cohort analysis
O’Grady T, Rinaldi S, Michels K, Adami H, Buring J, Chen Y, Clendenen T, D’Aloisio A, DeHart J, Franceschi S, Freedman N, Gierach G, Giles G, Lacey J, Lee I, Liao L, Linet M, McCullough M, Patel A, Prizment A, Robien K, Sandler D, Stolzenberg-Solomon R, Weiderpass E, White E, Wolk A, Zheng W, de Gonzalez A, Kitahara C. Association of hormonal and reproductive factors with differentiated thyroid cancer risk in women: a pooled prospective cohort analysis. International Journal Of Epidemiology 2023, 53: dyad172. PMID: 38110618, PMCID: PMC10859160, DOI: 10.1093/ije/dyad172.Peer-Reviewed Original ResearchConceptsThyroid cancer riskRisk of DTCDTC riskCancer riskMultivariable-adjusted Cox proportional hazards modelsMenopausal hormone therapy useHazard ratioFactors associated with higher riskEstimate hazard ratiosHormonal factorsOral contraceptivesHormone therapy useFactor associated with lower riskCox proportional hazards modelsProspective cohort analysisIncidence of differentiated thyroid cancerPost-menopausal statusMenopausal hormone therapyProportional hazards modelExposure misclassificationReproductive factorsPre-diagnosticTherapy useEvaluate associationsSex steroid hormonesEstimating dose-response relationships for vitamin D with coronary heart disease, stroke, and all-cause mortality: observational and Mendelian randomisation analyses
Collaboration E, Sofianopoulou E, Kaptoge S, Afzal S, Jiang T, Gill D, Gundersen T, Bolton T, Allara E, Arnold M, Mason A, Chung R, Pennells L, Shi F, Sun L, Willeit P, Forouhi N, Langenberg C, Sharp S, Panico S, Engström G, Melander O, Tong T, Perez-Cornago A, Norberg M, Johansson I, Katzke V, Srour B, Sánchez M, Redondo-Sánchez D, Olsen A, Dahm C, Overvad K, Brustad M, Skeie G, Moreno-Iribas C, Onland-Moret N, van der Schouw Y, Tsilidis K, Heath A, Agnoli C, Krogh V, de Boer I, Kobylecki C, Çolak Y, Zittermann A, Sundström J, Welsh P, Weiderpass E, Aglago E, Ferrari P, Clarke R, Boutron M, Severi G, MacDonald C, Providencia R, Masala G, Zamora-Ros R, Boer J, Verschuren M, Cawthon P, Schierbeck L, Cooper C, Schulze M, Bergmann M, Hannemann A, Kiechl S, Brenner H, van Schoor N, Albertorio J, Sacerdote C, Linneberg A, Kårhus L, Huerta J, Imaz L, Joergensen C, Ben-Shlomo Y, Lundqvist A, Gallacher J, Sattar N, Wood A, Wareham N, Nordestgaard B, Di Angelantonio E, Danesh J, Butterworth A, Burgess S. Estimating dose-response relationships for vitamin D with coronary heart disease, stroke, and all-cause mortality: observational and Mendelian randomisation analyses. The Lancet Diabetes & Endocrinology 2023, 12: e2-e11. PMID: 38048800, PMCID: PMC7615586, DOI: 10.1016/s2213-8587(23)00287-5.Peer-Reviewed Original ResearchConceptsMendelian randomisation analysisCoronary heart diseaseRandomisation analysesAll-cause mortalityMortality outcomesFatal ischaemic heart diseaseHeart diseaseIncident coronary heart diseaseHistory of coronary heart diseasePopulation-based cohort studyHealth Data Research UKCause-specific mortality outcomesNational Institute for Health ResearchMendelian randomisation frameworkDose-response relationshipIndividuals of European ancestryRisk of coronary heart diseaseRandomised trials of vitamin D supplementationLow vitamin D statusBritish Heart FoundationCancer Research UKInternational Agency for Research on CancerMiddle-aged individualsIschaemic heart diseaseMedical Research CouncilBody mass index and cancer risk among adults with and without cardiometabolic diseases: evidence from the EPIC and UK Biobank prospective cohort studies
Fontvieille E, Viallon V, Recalde M, Cordova R, Jansana A, Peruchet-Noray L, Lennon H, Heath A, Aune D, Christakoudi S, Katzke V, Kaaks R, Inan-Eroglu E, Schulze M, Mellemkjær L, Tjønneland A, Overvad K, Farràs M, Petrova D, Amiano P, Chirlaque M, Moreno-Iribas C, Tin Tin S, Masala G, Sieri S, Ricceri F, Panico S, May A, Monninkhof E, Weiderpass E, Gunter M, Ferrari P, Freisling H. Body mass index and cancer risk among adults with and without cardiometabolic diseases: evidence from the EPIC and UK Biobank prospective cohort studies. BMC Medicine 2023, 21: 418. PMID: 37993940, PMCID: PMC10666332, DOI: 10.1186/s12916-023-03114-z.Peer-Reviewed Original ResearchConceptsRisk due to interactionObesity-related cancersRisk of obesity-related cancersBody mass indexHigher body mass indexCardiometabolic diseasesJoint associationsHazard ratioCancer riskIncidence of obesity-related cancersJoint association of body mass indexCardiovascular diseaseConfidence intervalsRisk of overall cancerExcess risk due to interactionAssociation of body mass indexSurrogate measure of adiposityUK Biobank prospective cohortCategories of overweight/obesityUK Biobank (UKBAdditive interactionMass indexCardiometabolic disease statusParticipant data meta-analysisCancer risk reductionUltra-processed foods, adiposity and risk of head and neck cancer and oesophageal adenocarcinoma in the European Prospective Investigation into Cancer and Nutrition study: a mediation analysis
Morales-Berstein F, Biessy C, Viallon V, Goncalves-Soares A, Casagrande C, Hémon B, Kliemann N, Cairat M, Blanco Lopez J, Al Nahas A, Chang K, Vamos E, Rauber F, Bertazzi Levy R, Barbosa Cunha D, Jakszyn P, Ferrari P, Vineis P, Masala G, Catalano A, Sonestedt E, Borné Y, Katzke V, Bajracharya R, Agnoli C, Guevara M, Heath A, Radoï L, Mancini F, Weiderpass E, Huerta J, Sánchez M, Tjønneland A, Kyrø C, Schulze M, Skeie G, Lukic M, Braaten T, Gunter M, Millett C, Agudo A, Brennan P, Borges M, Richmond R, Richardson T, Davey Smith G, Relton C, Huybrechts I. Ultra-processed foods, adiposity and risk of head and neck cancer and oesophageal adenocarcinoma in the European Prospective Investigation into Cancer and Nutrition study: a mediation analysis. European Journal Of Nutrition 2023, 63: 377-396. PMID: 37989797, PMCID: PMC10899298, DOI: 10.1007/s00394-023-03270-1.Peer-Reviewed Original ResearchConceptsConsumption of ultra-processed foodsUltra-processed foodsWaist-to-hip ratioRisk of head and neck cancerUltra-processed food consumptionOesophageal adenocarcinoma riskEuropean Prospective InvestigationBody mass indexHead and neck cancerIncreased risk of HNCHigher consumption of ultra-processed foodsHead and neck cancer riskProspective InvestigationCancer and NutritionNegative control analysesOesophageal adenocarcinomaWaist-to-hipNegative control outcomesAssociated with greater riskMediation analysisNeck cancerAccidental deathEPIC participantsMass indexGreater riskDietary intakes of dioxins and polychlorobiphenyls (PCBs) and mortality: EPIC cohort study in 9 European countries
Fiolet T, Nicolas G, Casagrande C, Horvath Z, Frenoy P, Weiderpass E, Gunter M, Manjer J, Sonestedt E, Palli D, Simeon V, Tumino R, Bueno-de-Mesquita B, Huerta J, Rodriguez-Barranco M, Abilleira E, Sacerdote C, Schulze M, Heath A, Rylander C, Skeie G, Nøst T, Tjønneland A, Olsen A, Pala V, Kvaskoff M, Huybrechts I, Mancini F. Dietary intakes of dioxins and polychlorobiphenyls (PCBs) and mortality: EPIC cohort study in 9 European countries. International Journal Of Hygiene And Environmental Health 2023, 255: 114287. PMID: 37989047, DOI: 10.1016/j.ijheh.2023.114287.Peer-Reviewed Original ResearchConceptsDietary intakeCause mortalityCohort studyIntake of dioxinsCancer mortalityGeneral populationEPIC cohort studyMultivariable Cox regressionEuropean Prospective InvestigationCardiovascular-specific mortalityMain exposure sourceNDL-PCBsFood consumption dataFood contamination dataSerum/plasmaNon-linear associationNutrition CohortCardiovascular mortalityHazard ratioCox regressionNon-monotonic dose responsesProspective InvestigationEuropean Food Safety AuthorityMortalityInconsistent associationsOpium use and risk of colorectal cancer: a multi-center case-referent study in Iran
Hadji M, Marzban M, Rashidian H, Naghibzadeh-Tahami A, Gholipour M, Mohebbi E, Safari-Faramani R, Seyyedsalehi M, Hosseini B, Alizadeh-Navaei R, Rezaianzadeh A, Moradi A, ShahidSales S, Najafi F, Moazed V, Haghdoost A, Rahimi-Movaghar A, Etemadi A, Malekzadeh R, Boffetta P, Weiderpass E, Kamangar F, Zendehdel K, Pukkala E. Opium use and risk of colorectal cancer: a multi-center case-referent study in Iran. Acta Oncologica 2023, 62: 1661-1668. PMID: 37934078, DOI: 10.1080/0284186x.2023.2276326.Peer-Reviewed Original ResearchConceptsRisk of colorectal cancerCase-referent studyOpium useColorectal cancerIncreased risk of CRCOdds ratioMultivariable unconditional logistic regression modelOccupational physical activityUnconditional logistic regression modelsIncreased risk of cancerColorectal cancer casesIncreased riskConsumption of red meatMeasure odds ratiosRisk of cancerInternational Agency for Cancer ResearchLogistic regression modelsPhysical activityTrained interviewersSocioeconomic statusPotential confoundersMarital statusFamily historyRed meatOpium consumptionPrediagnostic selenium status, selenoprotein gene variants and association with breast cancer risk in a European cohort study
Hughes D, Schomburg L, Jenab M, Biessy C, Méplan C, Moskal A, Sun Q, Demircan K, Fedirko V, Weiderpass E, Mukhtar M, Olsen A, Tjønneland A, Overvad K, Schulze M, Nøst T, Skeie G, Olsen K, Ricceri F, Grioni S, Palli D, Masala G, Tumino R, Pasanisi F, Amiano P, Colorado Yohar S, Agudo A, Sánchez M, Ardanaz E, Sund M, Andersson A, Perez-Cornago A, Travis R, Heath A, Dossus L. Prediagnostic selenium status, selenoprotein gene variants and association with breast cancer risk in a European cohort study. Free Radical Biology And Medicine 2023, 209: 381-393. PMID: 37923090, DOI: 10.1016/j.freeradbiomed.2023.10.401.Peer-Reviewed Original ResearchConceptsAssociated with BC riskBC riskCase-control pairsOdds ratioMultivariable-adjusted logistic regression modelsBreast cancer riskInfluence BC riskCancer and NutritionConfidence intervalsEuropean Prospective InvestigationHigher risk of BCPremenopausal BC riskRisk of BCPrevent breast cancerAssociated with lower riskEuropean cohort studiesBreast cancerGenetic variant associationsLogistic regression modelsGlutathione peroxidase 3Multiple testing correctionStatistically significant associationPremenopausal BCCancer riskVariant associationsLatin America and the Caribbean Code Against Cancer 1st Edition: A landmark for cancer prevention in the region
Schüz J, Espina C, Carvalho A, Maza M, Luciani S, Cazap E, Hennis A, Weiderpass E. Latin America and the Caribbean Code Against Cancer 1st Edition: A landmark for cancer prevention in the region. Cancer Epidemiology 2023, 86: 102453. PMID: 37852730, DOI: 10.1016/j.canep.2023.102453.Peer-Reviewed Original ResearchProspective and Mendelian randomization analyses on the association of circulating fatty acid binding protein 4 (FABP-4) and risk of colorectal cancer
Nimptsch K, Aleksandrova K, Pham T, Papadimitriou N, Janke J, Christakoudi S, Heath A, Olsen A, Tjønneland A, Schulze M, Katzke V, Kaaks R, van Guelpen B, Harbs J, Palli D, Macciotta A, Pasanisi F, Yohar S, Guevara M, Amiano P, Grioni S, Jakszyn P, Figueiredo J, Samadder N, Li C, Moreno V, Potter J, Schoen R, Um C, Weiderpass E, Jenab M, Gunter M, Pischon T. Prospective and Mendelian randomization analyses on the association of circulating fatty acid binding protein 4 (FABP-4) and risk of colorectal cancer. BMC Medicine 2023, 21: 391. PMID: 37833736, PMCID: PMC10576353, DOI: 10.1186/s12916-023-03104-1.Peer-Reviewed Original ResearchConceptsColorectal cancer riskColorectal cancer casesMendelian randomizationColorectal cancerEpidemiology of Colorectal Cancer ConsortiumAssociated with colorectal cancer riskTwo-sample Mendelian randomization studyColon Cancer Family RegistryPublished genome-wide association studiesColorectal Cancer ConsortiumCancer Family RegistryConditional logistic regression modelsMendelian randomization analysisMendelian randomization studiesCancer and NutritionEuropean Prospective InvestigationNested case-control studyGenome-wide association studiesLogistic regression modelsCase-control studyDevelopment of colorectal cancerFamily RegistryStatistically significant associationCancer ConsortiumCancer riskDietary amino acids and risk of stroke subtypes: a prospective analysis of 356,000 participants in seven European countries
Tong T, Clarke R, Schmidt J, Huybrechts I, Noor U, Forouhi N, Imamura F, Travis R, Weiderpass E, Aleksandrova K, Dahm C, van der Schouw Y, Overvad K, Kyrø C, Tjønneland A, Kaaks R, Katzke V, Schiborn C, Schulze M, Mayen-Chacon A, Masala G, Sieri S, de Magistris M, Tumino R, Sacerdote C, Boer J, Verschuren W, Brustad M, Nøst T, Crous-Bou M, Petrova D, Amiano P, Huerta J, Moreno-Iribas C, Engström G, Melander O, Johansson K, Lindvall K, Aglago E, Heath A, Butterworth A, Danesh J, Key T. Dietary amino acids and risk of stroke subtypes: a prospective analysis of 356,000 participants in seven European countries. European Journal Of Nutrition 2023, 63: 209-220. PMID: 37804448, PMCID: PMC10799144, DOI: 10.1007/s00394-023-03251-4.Peer-Reviewed Original ResearchConceptsRisk of ischaemic strokeHaemorrhagic strokeRisk of stroke subtypesMultivariable-adjusted Cox regression modelsHazard ratioIschaemic strokeStroke subtypesCountry-specific dietary questionnairesBlood pressureConfidence intervalsEstimate hazard ratiosProline intakeMethodsWe analysed dataMultiple testingStatistically significant associationDietary recallsDietary questionnaireInverse associationCox regression modelsDiastolic blood pressureEPIC studyHigher intakeDietary amino acidsDietary intakeMutual adjustmentEthnic Differences in the Association Between Age at Natural Menopause and Risk of Type 2 Diabetes Among Postmenopausal Women: A Pooled Analysis of Individual Data From 13 Cohort Studies.
Chung H, Dobson A, Hayashi K, Hardy R, Kuh D, Anderson D, van der Schouw Y, Greenwood D, Cade J, Demakakos P, Brunner E, Eastwood S, Sandin S, Weiderpass E, Mishra G. Ethnic Differences in the Association Between Age at Natural Menopause and Risk of Type 2 Diabetes Among Postmenopausal Women: A Pooled Analysis of Individual Data From 13 Cohort Studies. Diabetes Care 2023, 46: 2024-2034. PMID: 37747341, PMCID: PMC10696407, DOI: 10.2337/dc23-1209.Peer-Reviewed Original ResearchConceptsIncreased risk of T2DPremature ovarian insufficiencyRisk of T2DType 2 diabetesPooled individual-level dataCohort studyHazard ratioIncident type 2 diabetesRisk of type 2 diabetesEthnic groupsNatural menopauseChinese womenEarly menopauseIncreased riskYears of follow-upIndividual-level dataBirth yearEducation levelInvestigate associationsRisk estimatesOvarian insufficiencyPostmenopausal womenEthnic differencesRisk factorsPooled analysis