2024
Healthy lifestyle change and all-cause and cancer mortality in the European Prospective Investigation into Cancer and Nutrition cohort
Matta K, Viallon V, Botteri E, Peveri G, Dahm C, Nannsen A, Olsen A, Tjønneland A, Elbaz A, Artaud F, Marques C, Kaaks R, Katzke V, Schulze M, Llanaj E, Masala G, Pala V, Panico S, Tumino R, Ricceri F, Derksen J, Nøst T, Sandanger T, Borch K, Quirós J, Castro-Espin C, Sánchez M, Atxega A, Cirera L, Guevara M, Manjer J, Tin Tin S, Heath A, Touvier M, Goldberg M, Weiderpass E, Gunter M, Freisling H, Riboli E, Ferrari P. Healthy lifestyle change and all-cause and cancer mortality in the European Prospective Investigation into Cancer and Nutrition cohort. BMC Medicine 2024, 22: 210. PMID: 38807179, PMCID: PMC11134634, DOI: 10.1186/s12916-024-03362-7.Peer-Reviewed Original ResearchConceptsHealthy lifestyle indexAssociated with all-causeHealthy lifestyle changesEuropean Prospective InvestigationRisk of deathCancer mortalityFollow-up questionnaireAll-causeLifestyle changesProspective InvestigationRate advancement periodsUnhealthy lifestyle changesRisk of noncommunicable diseasesCancer and NutritionCancer-free adultsBody mass indexBackgroundHealthy lifestylesLifestyle behaviorsNutrition CohortLifestyle indexLifestyle ProfilePhysical activityAssociated with mortalityNoncommunicable diseasesChange scoresOccupation and tongue cancer in Nordic countries
Peltonen J, Nikkilä R, Al-Samadi A, Mäkitie A, Martinsen J, Kjaerheim K, Lynge E, Sparen P, Tryggvadottir L, Weiderpass E, Salo T, Pukkala E. Occupation and tongue cancer in Nordic countries. BMC Oral Health 2024, 24: 506. PMID: 38685000, PMCID: PMC11059716, DOI: 10.1186/s12903-024-04172-2.Peer-Reviewed Original ResearchConceptsStandardized incidence ratioNordic Occupational CancerNational incidence ratesTongue cancerBeverage workersConsumption of alcoholEffects of carcinogen exposureSignificant SIRsIncidence ratiosResultsAmong menInactive personsOccupational cancerIncidence rateNordic countriesOccupational categoriesMethodsThe dataArtistic workersRisk variationMale farmersConclusionsThese findingsCarcinogen exposureWorkersForestry workersCancerTobaccoDietary intake of plant- and animal-derived protein and incident cardiovascular diseases: the pan-European EPIC-CVD case–cohort study
Zheng J, Steur M, Imamura F, Freisling H, Johnson L, van der Schouw Y, Tong T, Weiderpass E, Bajracharya R, Crous-Bou M, Dahm C, Heath A, Ibsen D, Jannasch F, Katzke V, Masala G, Moreno-Iribas C, Sacerdote C, Schulze M, Sieri S, Wareham N, Danesh J, Butterworth A, Forouhi N. Dietary intake of plant- and animal-derived protein and incident cardiovascular diseases: the pan-European EPIC-CVD case–cohort study. American Journal Of Clinical Nutrition 2024, 119: 1164-1174. PMID: 38479550, PMCID: PMC11130694, DOI: 10.1016/j.ajcnut.2024.03.006.Peer-Reviewed Original ResearchConceptsIschemic heart diseaseDietary protein intakeProtein intakeCase-cohort studyCardiovascular diseaseIncident cardiovascular diseaseFatal strokeAssociated with lower incidenceIncidence of fatal strokeRisk of cardiovascular diseaseEuropean Prospective InvestigationPrentice-weighted Cox regressionAssociated with incident cardiovascular diseaseOverall CVDIncident CVD casesIntake of plantMacronutrient intakeStroke incidenceProtein consumptionSubcohort membersIsocaloric substitutionDietary patternsDietary intakeNever smokersProspective InvestigationManaging menopause after cancer
Hickey M, Basu P, Sassarini J, Stegmann M, Weiderpass E, Nakawala Chilowa K, Yip C, Partridge A, Brennan D. Managing menopause after cancer. The Lancet 2024, 403: 984-996. PMID: 38458217, DOI: 10.1016/s0140-6736(23)02802-7.Peer-Reviewed Original ResearchConceptsPremature ovarian insufficiencyMenopausal symptomsRisk of chronic conditionsLong-term effects of cancer treatmentHormone therapyOvarian insufficiencyPatient-focused modelModels of careVasomotor symptomsBreast cancerEffects of cancer treatmentCancer treatmentSexual dysfunctionHigh-income countriesMenopausal hormone therapyQuality of lifeTreatment-induced symptomsLow-income countriesNon-hormonal treatmentsNon-hormonal optionsChronic conditionsManaging menopausal symptomsManaging menopauseDiagnose menopauseVaginal estrogenBMI and breast cancer risk around age at menopause
Von Holle A, Adami H, Baglietto L, Berrington de Gonzalez A, Bertrand K, Blot W, Chen Y, DeHart J, Dossus L, Eliassen A, Fournier A, Garcia-Closas M, Giles G, Guevara M, Hankinson S, Heath A, Jones M, Joshu C, Kaaks R, Kirsh V, Kitahara C, Koh W, Linet M, Park H, Masala G, Mellemkjaer L, Milne R, O'Brien K, Palmer J, Riboli E, Rohan T, Shrubsole M, Sund M, Tamimi R, Tin Tin S, Visvanathan K, Vermeulen R, Weiderpass E, Willett W, Yuan J, Zeleniuch-Jacquotte A, Nichols H, Sandler D, Swerdlow A, Schoemaker M, Weinberg C. BMI and breast cancer risk around age at menopause. Cancer Epidemiology 2024, 89: 102545. PMID: 38377945, PMCID: PMC10942753, DOI: 10.1016/j.canep.2024.102545.Peer-Reviewed Original ResearchConceptsBreast cancer riskCancer riskHazard ratioBreast cancer hazard ratioCancer hazard ratioFive-unit incrementNatural menopauseBreast cancer etiologyHigher body mass indexLoss to follow-upAssociated with decreased riskBreast cancer diagnosisMenopausal status groupsBody mass indexYears age rangeMenopausal hormone therapyPrimary time scalePerson-timeCancer etiologyLoss of ovarian functionCancer diagnosisMass indexBMIPositive associationStatus groupsCirculating endogenous sex steroids and risk of differentiated thyroid carcinoma in men and women
Rinaldi S, Dossus L, Keski‐Rahkonen P, Kiss A, Navionis A, Biessy C, Travis R, Weiderpass E, Romieu I, Eriksen A, Tjonneland A, Kvaskoff M, Canonico M, Truong T, Katzke V, Kaaks R, Catalano A, Panico S, Masala G, Tumino R, Lukic M, Olsen K, Zamora‐Ros R, Santiuste C, Atxega A, Guevara M, Rodriguez‐Barranco M, Sandstrom M, Hennings J, Almquist M, Kouassivi E, Christakoudi S, Gunter M, Franceschi S. Circulating endogenous sex steroids and risk of differentiated thyroid carcinoma in men and women. International Journal Of Cancer 2024, 154: 2064-2074. PMID: 38357914, DOI: 10.1002/ijc.34872.Peer-Reviewed Original ResearchConceptsSex hormone binding globulinSex steroid hormonesThyroid cancerRisk of differentiated thyroid carcinomaOdds ratioSex steroidsSex hormone binding globulin concentrationsSteroid hormonesCancer-free controlsPre-menopausal womenRisk of differentiated TCEuropean Prospective InvestigationPost-menopausal womenEndogenous sex steroidsBorderline significant increaseConditional logistic regression modelsSex steroid productionNo significant associationCirculating sex steroidsCirculating sex steroid hormonesPostmenopausal womenConcentrations of testosteroneProgesterone/estradiol ratioThyroid carcinomaBorderline decreaseFemale reproductive histories and the risk of chronic obstructive pulmonary disease
Liang C, Chung H, Dobson A, Sandin S, Weiderpass E, Mishra G. Female reproductive histories and the risk of chronic obstructive pulmonary disease. Thorax 2024, 79: 508-514. PMID: 38350732, DOI: 10.1136/thorax-2023-220388.Peer-Reviewed Original ResearchConceptsRisk of chronic obstructive pulmonary diseaseChronic obstructive pulmonary diseaseFemale reproductive factorsReproductive factorsObstructive pulmonary diseaseNatural menopauseBirth yearIncreased risk of COPDPulmonary diseaseBody mass indexDevelopment of chronic obstructive pulmonary diseaseEducation levelCox regression modelsMass indexReproductive historyIncreased riskCohort differencesStillbirthRegression modelsFemale reproductive historyMenarcheMedian follow-upWomenFemale hormonal environmentCohort
2023
Association of hormonal and reproductive factors with differentiated thyroid cancer risk in women: a pooled prospective cohort analysis
O’Grady T, Rinaldi S, Michels K, Adami H, Buring J, Chen Y, Clendenen T, D’Aloisio A, DeHart J, Franceschi S, Freedman N, Gierach G, Giles G, Lacey J, Lee I, Liao L, Linet M, McCullough M, Patel A, Prizment A, Robien K, Sandler D, Stolzenberg-Solomon R, Weiderpass E, White E, Wolk A, Zheng W, de Gonzalez A, Kitahara C. Association of hormonal and reproductive factors with differentiated thyroid cancer risk in women: a pooled prospective cohort analysis. International Journal Of Epidemiology 2023, 53: dyad172. PMID: 38110618, PMCID: PMC10859160, DOI: 10.1093/ije/dyad172.Peer-Reviewed Original ResearchConceptsThyroid cancer riskRisk of DTCDTC riskCancer riskMultivariable-adjusted Cox proportional hazards modelsMenopausal hormone therapy useHazard ratioFactors associated with higher riskEstimate hazard ratiosHormonal factorsOral contraceptivesHormone therapy useFactor associated with lower riskCox proportional hazards modelsProspective cohort analysisIncidence of differentiated thyroid cancerPost-menopausal statusMenopausal hormone therapyProportional hazards modelExposure misclassificationReproductive factorsPre-diagnosticTherapy useEvaluate associationsSex steroid hormonesPrediagnostic selenium status, selenoprotein gene variants and association with breast cancer risk in a European cohort study
Hughes D, Schomburg L, Jenab M, Biessy C, Méplan C, Moskal A, Sun Q, Demircan K, Fedirko V, Weiderpass E, Mukhtar M, Olsen A, Tjønneland A, Overvad K, Schulze M, Nøst T, Skeie G, Olsen K, Ricceri F, Grioni S, Palli D, Masala G, Tumino R, Pasanisi F, Amiano P, Colorado Yohar S, Agudo A, Sánchez M, Ardanaz E, Sund M, Andersson A, Perez-Cornago A, Travis R, Heath A, Dossus L. Prediagnostic selenium status, selenoprotein gene variants and association with breast cancer risk in a European cohort study. Free Radical Biology And Medicine 2023, 209: 381-393. PMID: 37923090, DOI: 10.1016/j.freeradbiomed.2023.10.401.Peer-Reviewed Original ResearchConceptsAssociated with BC riskBC riskCase-control pairsOdds ratioMultivariable-adjusted logistic regression modelsBreast cancer riskInfluence BC riskCancer and NutritionConfidence intervalsEuropean Prospective InvestigationHigher risk of BCPremenopausal BC riskRisk of BCPrevent breast cancerAssociated with lower riskEuropean cohort studiesBreast cancerGenetic variant associationsLogistic regression modelsGlutathione peroxidase 3Multiple testing correctionStatistically significant associationPremenopausal BCCancer riskVariant associationsProspective and Mendelian randomization analyses on the association of circulating fatty acid binding protein 4 (FABP-4) and risk of colorectal cancer
Nimptsch K, Aleksandrova K, Pham T, Papadimitriou N, Janke J, Christakoudi S, Heath A, Olsen A, Tjønneland A, Schulze M, Katzke V, Kaaks R, van Guelpen B, Harbs J, Palli D, Macciotta A, Pasanisi F, Yohar S, Guevara M, Amiano P, Grioni S, Jakszyn P, Figueiredo J, Samadder N, Li C, Moreno V, Potter J, Schoen R, Um C, Weiderpass E, Jenab M, Gunter M, Pischon T. Prospective and Mendelian randomization analyses on the association of circulating fatty acid binding protein 4 (FABP-4) and risk of colorectal cancer. BMC Medicine 2023, 21: 391. PMID: 37833736, PMCID: PMC10576353, DOI: 10.1186/s12916-023-03104-1.Peer-Reviewed Original ResearchConceptsColorectal cancer riskColorectal cancer casesMendelian randomizationColorectal cancerEpidemiology of Colorectal Cancer ConsortiumAssociated with colorectal cancer riskTwo-sample Mendelian randomization studyColon Cancer Family RegistryPublished genome-wide association studiesColorectal Cancer ConsortiumCancer Family RegistryConditional logistic regression modelsMendelian randomization analysisMendelian randomization studiesCancer and NutritionEuropean Prospective InvestigationNested case-control studyGenome-wide association studiesLogistic regression modelsCase-control studyDevelopment of colorectal cancerFamily RegistryStatistically significant associationCancer ConsortiumCancer riskEthnic Differences in the Association Between Age at Natural Menopause and Risk of Type 2 Diabetes Among Postmenopausal Women: A Pooled Analysis of Individual Data From 13 Cohort Studies.
Chung H, Dobson A, Hayashi K, Hardy R, Kuh D, Anderson D, van der Schouw Y, Greenwood D, Cade J, Demakakos P, Brunner E, Eastwood S, Sandin S, Weiderpass E, Mishra G. Ethnic Differences in the Association Between Age at Natural Menopause and Risk of Type 2 Diabetes Among Postmenopausal Women: A Pooled Analysis of Individual Data From 13 Cohort Studies. Diabetes Care 2023, 46: 2024-2034. PMID: 37747341, PMCID: PMC10696407, DOI: 10.2337/dc23-1209.Peer-Reviewed Original ResearchConceptsIncreased risk of T2DPremature ovarian insufficiencyRisk of T2DType 2 diabetesPooled individual-level dataCohort studyHazard ratioIncident type 2 diabetesRisk of type 2 diabetesEthnic groupsNatural menopauseChinese womenEarly menopauseIncreased riskYears of follow-upIndividual-level dataBirth yearEducation levelInvestigate associationsRisk estimatesOvarian insufficiencyPostmenopausal womenEthnic differencesRisk factorsPooled analysisAge at Menopause and the Risk of Stroke: Observational and Mendelian Randomization Analysis in 204 244 Postmenopausal Women
Tschiderer L, Peters S, van der Schouw Y, van Westing A, Tong T, Willeit P, Seekircher L, Moreno‐Iribas C, Huerta J, Crous‐Bou M, Söderholm M, Schulze M, Johansson C, Själander S, Heath A, Macciotta A, Dahm C, Ibsen D, Pala V, Mellemkjær L, Burgess S, Wood A, Kaaks R, Katzke V, Amiano P, Rodriguez‐Barranco M, Engström G, Weiderpass E, Tjønneland A, Halkjær J, Panico S, Danesh J, Butterworth A, Onland‐Moret N. Age at Menopause and the Risk of Stroke: Observational and Mendelian Randomization Analysis in 204 244 Postmenopausal Women. Journal Of The American Heart Association 2023, 12: e030280. PMID: 37681566, PMCID: PMC10547274, DOI: 10.1161/jaha.123.030280.Peer-Reviewed Original ResearchConceptsMendelian randomization analysisRisk of strokeStatistically significant associationRandomization analysisSignificant associationHistory of strokeEPIC-CVDPooled mean ageHigh risk of strokeUK BiobankYears younger ageBaseline ageHazard ratioStroke subtypesObservational studyPooled hazard ratioHemorrhagic strokeEarly menopauseYounger ageMean ageHigh riskMedian follow-upStrokeRegression analysisWomen
2019
Global, regional, and national burden of suicide mortality 1990 to 2016: systematic analysis for the Global Burden of Disease Study 2016
Naghavi M, Collaborators G, Orpana H, Marczak L, Arora M, Abbasi N, Abdulkader R, Abebe Z, Abraha H, Afarideh M, Afshari, Ahmadi A, Aichour A, Aichour I, Aichour M, Akseer N, Al-Raddadi R, Alahdab F, Alkerwi A, Allebeck P, Alvis-Guzman N, Anber N, Anjomshoa M, Antonio C, Arora A, Aryal K, Asgedom S, Awasthi A, Quintanilla B, Badali H, Barker-Collo S, Bärnighausen T, Bazargan-Hejazi S, Benjet C, Bensenor I, Berfeld N, Beuran M, Bhutta Z, Biadgo B, Bililign N, Borges G, Borschmann R, Brazinova A, Breitborde N, Brugha T, Butt Z, Carrero J, Carvalho F, Malta D, Castañeda-Orjuela C, Catalá-López F, Ciobanu L, Dachew B, Dandona L, Dandona R, Dargan P, Daryani A, Davitoiu D, Davletov K, Degenhardt L, Demoz G, Jarlais D, Dharmaratne S, Djalalinia S, Doan L, Doku D, Dubey M, El-Khatib Z, Eskandarieh S, Esteghamati A, Esteghamati S, Faro A, Farzadfar F, Fekadu W, Fernandes E, Ferrari A, Filip I, Fischer F, Foreman K, Fukumoto T, Gebre A, Grosso G, Gupta R, Haagsma J, Bidgoli H, Haj-Mirzaian A, Hamidi S, Hankey G, Haro J, Hassen H, Hay S, Heidari B, Hendrie D, Rad E, Hosseini S, Hostiuc S, Irvani S, Islam M, Jakovljevic M, James S, Jayatilleke A, Jha R, Jonas J, Jozwiak J, Kadel R, Kahsay A, Kasaeian A, Kassa G, Kawakami N, Kefale A, Kemp G, Khader Y, Khafaie M, Khalil I, Khan E, Khan M, Khan M, Khang Y, Khubchandani J, Kiadaliri A, Kieling C, Kim Y, Kisa A, Knudsen A, Kokubo Y, Koyanagi A, Krish V, Defo B, Kumar G, Kumar M, Lamichhane P, Lang J, Latifi A, Lee P, Leung J, Lim L, Lopez A, Lorkowski S, Lotufo P, Lozano R, Lunevicius R, Mahesh P, Majdan M, Majdzadeh R, Malekzadeh R, Manda A, Mansournia M, Mantovani L, Maravilla J, Martinez-Raga J, Mathur M, Maulik P, McGrath J, Mehrotra R, Mekonen T, Mendoza W, Meretoja T, Mestrovic T, Miller T, Mini G, Mirrakhimov E, Mitchell P, Moazen B, Mohammad K, Mohammadi M, Mohammed S, Mokdad A, Monasta L, Moosazadeh M, Moradi G, Moradi-Lakeh M, Moradinazar M, Velásquez I, Morisaki N, Morrison S, Moschos M, Mousavi S, Mustafa G, Nagel G, Naheed A, Naik G, Najafi F, Negoi I, Negoi R, Nguyen H, Nguyen L, Nixon M, Ofori-Asenso R, Ogbo F, Oh I, Olagunju A, Olagunju T, Øverland S, Owolabi M, Panda-Jonas S, Parry C, Pati S, Patten S, Patton G, Petzold M, Phillips M, Plana-Ripoll O, Postma M, Pourshams A, Poustchi H, Qorbani M, Radfar A, Rafay A, Rafiei A, Rahim F, Rahimi-Movaghar A, Rahimi-Movaghar V, Rahman M, Kumar R, Rezaeian S, Roever L, Ronfani L, Roshandel G, Rostami A, Sachdev P, Safari H, Safiri S, Salamati P, Salimi Y, Salomon J, Samy A, Santos I, Santric-Milicevic M, Sartorius B, Sarvi S, Satpathy M, Sawhney M, Schwebel D, Sepanlou S, Shaikh M, Sharif M, Shibuya K, Shigematsu M, Shiri R, Shiue I, Siabani S, Siddiqi T, Sigfusdottir I, Silva J, Singh J, Filho A, Sobhani S, Stein D, Stein M, Sufiyan M, Sunguya B, Tabarés-Seisdedos R, Tabb K, Tavakkoli M, Tehrani-Banihashemi A, Temsah M, Topor-Madry R, Tran B, Tran K, Ullah I, Unutzer J, Usman M, Uthman O, Valdez P, Vasankari T, Vasconcelos C, Vlassov V, Vos T, Vujcic I, Waheed Y, Wang Y, Weiderpass E, Werdecker A, Westerman R, Whiteford H, Wyper G, Yaseri M, Yimer E, Yisma E, Yonemoto N, Yoon S, Yotebieng M, Yousefifard M, Yu C, Zaidi Z, Zamani M, Murray C, Naghavi M. Global, regional, and national burden of suicide mortality 1990 to 2016: systematic analysis for the Global Burden of Disease Study 2016. The BMJ 2019, 364: l94. PMID: 31339847, PMCID: PMC6598639, DOI: 10.1136/bmj.l94.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge DistributionAge FactorsAgedCause of DeathCross-Cultural ComparisonData Interpretation, StatisticalFemaleGlobal Burden of DiseaseGlobal HealthHumansLife ExpectancyMaleMortalityOutcome Assessment, Health CareSex DistributionSex FactorsSocioeconomic FactorsSuicideSuicide PreventionConceptsAge-standardised mortality ratesSuicide mortalityLevel of socio-demographic indexSocio-demographic indexLatin AmericaSouthern Latin AmericaEastern EuropeGlobal Burden of Disease StudyGlobal ageBurden of Disease StudyAsia-PacificWestern EuropeAge-standardised ratesCentral AsiaVulnerable populationsStandardised ratesGlobal burdenCountriesGlobalSuicide prevention strategiesEuropeAge groupsMortality rateDisease StudySuicide