2024
Circulating endogenous sex steroids and risk of differentiated thyroid carcinoma in men and women
Rinaldi S, Dossus L, Keski‐Rahkonen P, Kiss A, Navionis A, Biessy C, Travis R, Weiderpass E, Romieu I, Eriksen A, Tjonneland A, Kvaskoff M, Canonico M, Truong T, Katzke V, Kaaks R, Catalano A, Panico S, Masala G, Tumino R, Lukic M, Olsen K, Zamora‐Ros R, Santiuste C, Atxega A, Guevara M, Rodriguez‐Barranco M, Sandstrom M, Hennings J, Almquist M, Kouassivi E, Christakoudi S, Gunter M, Franceschi S. Circulating endogenous sex steroids and risk of differentiated thyroid carcinoma in men and women. International Journal Of Cancer 2024, 154: 2064-2074. PMID: 38357914, DOI: 10.1002/ijc.34872.Peer-Reviewed Original ResearchConceptsSex hormone binding globulinSex steroid hormonesThyroid cancerRisk of differentiated thyroid carcinomaOdds ratioSex steroidsSex hormone binding globulin concentrationsSteroid hormonesCancer-free controlsPre-menopausal womenRisk of differentiated TCEuropean Prospective InvestigationPost-menopausal womenEndogenous sex steroidsBorderline significant increaseConditional logistic regression modelsSex steroid productionNo significant associationCirculating sex steroidsCirculating sex steroid hormonesPostmenopausal womenConcentrations of testosteroneProgesterone/estradiol ratioThyroid carcinomaBorderline decrease
2023
Prediagnostic Hormone Levels and Risk of Testicular Germ Cell Tumors: A Nested Case-Control Study in the Janus Serum Bank.
Wu Z, Trabert B, Guillemette C, Caron P, Bradwin G, Graubard B, Weiderpass E, Ursin G, Langseth H, McGlynn K. Prediagnostic Hormone Levels and Risk of Testicular Germ Cell Tumors: A Nested Case-Control Study in the Janus Serum Bank. Cancer Epidemiology Biomarkers & Prevention 2023, 32: 1564-1571. PMID: 37619591, PMCID: PMC10655159, DOI: 10.1158/1055-9965.epi-23-0772.Peer-Reviewed Original ResearchConceptsTesticular germ cell tumorsDevelopment of testicular germ cell tumorsRisk of testicular germ cell tumorsGerm cell tumorsNested case-control studyFollicle-stimulating hormoneCase-control studyFSH levelsHigher FSH levelsSertoli cellsCell tumorsLuteinizing hormoneHormone levelsLevels of serum gonadotropinsTesticular germ cell tumour riskJanus Serum Bank CohortAssociated with TGCT riskSex hormone binding globulinIncreased FSH levelsConfidence intervalsMultivariate logistic regressionLevels of androgensSex steroid hormonesLH levelsBinding globulin